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Endothelial Cell-Specific Molecule 1 Proteins (ESM1)

ESM1 encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. Additionally we are shipping ESM1 Antibodies (57) and ESM1 Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ESM1 71690 Q9QYY7
ESM1 64536 P97682
ESM1 11082 Q9NQ30
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Top ESM1 Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$644.60
Details
HOST_Baculovirus infected Insect Cells Mouse His tag 50 μg Log in to see 16 Days
$250.80
Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Insect Cells Human His tag   50 μg Log in to see 5 Days
$340.73
Details
Insect Cells Mouse His tag   50 μg Log in to see 5 Days
$340.73
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,370.50
Details

ESM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, ,
Rat (Rattus) ,

Human , , , , ,
,

Top referenced ESM1 Proteins

  1. Human ESM1 Protein expressed in Escherichia coli (E. coli) - ABIN1098721 : Bechard, Meignin, Scherpereel, Oudin, Kervoaze, Bertheau, Janin, Tonnel, Lassalle: Characterization of the secreted form of endothelial-cell-specific molecule 1 by specific monoclonal antibodies. in Journal of vascular research 2000 (PubMed)
    Show all 2 references for ABIN1098721

More Proteins for Endothelial Cell-Specific Molecule 1 (ESM1) Interaction Partners

Mouse (Murine) Endothelial Cell-Specific Molecule 1 (ESM1) interaction partners

  1. Results reveal a novel pathway for endocan in the control of tumor growth, which involves inflammatory cells of the innate immunity.

  2. Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.

  3. This study shows endocan can elicit severe inflammatory responses and inhibiting endocan release offers a potential strategy for treating sepsis.

  4. endocan is normally present in the mouse brain and prior vascular perfusion with FITC may provide a useful tool for identify newly forming blood vessels.

  5. Mouse endocan serum level was measured at a median of 0.96 ng/mL and 1.08 ng/mL in 129Sv mice and C57bl6, respectively.

  6. A paracrine vasoregulatory pathway mediated by endothelial cell-derived ET-1 (show EDN1 Proteins) acting on the vascular smooth muscle ET(A (show EDNRA Proteins)) receptor.

  7. Results suggest that endocan (ESM-1)is preferentially expressed in tumor endothelium in vivo and that its expression is regulated by tumor-derived factors.

Human Endothelial Cell-Specific Molecule 1 (ESM1) interaction partners

  1. Results found that serum endocan levels were significantly lower in Alzheimer's disease (AD) patients with depression than in AD patients without depression or healthy controls suggesting that serum endocan levels might be associated with depression in AD.

  2. serum levels of endocan, a new biomarker of endothelial dysfunction, increase in obstructive sleep apnea subjects.

  3. Endocan may play a role in the progression of pregnancy and has a potential to be a new marker for the detection of pre-eclampsia

  4. Serum endocan concentrations were significantly elevated in women with pre-eclampsia versus normotensive controls, and concentrations seem to be associated with the severity of the disease.

  5. Suggest that serum endocan concentrations are elevated in patients with type 2 diabetes and decrease following anti-hyperglycemic treatment.

  6. Median maternal plasma endocan concentrations were higher in preeclampsia and lower in acute pyelonephritis with bacteremia than in uncomplicated pregnancy.

  7. Elevated endocan levels were more strongly associated with disease severity among Johnson Syndrome, Toxic Epidermal Necrolysis subjects than among less severe allergic reactions with skin involvement.

  8. Detection of ESM-1 levels in the serum may serve as a tumor biomarker for assessing prognosis in colorectal cancer.

  9. Serum endocan level is independently correlated with the presence and severity of coronary artery disease in hypertension patients.

  10. Serum ESM1 was significantly lower in type 2 diabetes patients than in controls.

ESM1 Protein Profile

Protein Summary

This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ESM1

  • endothelial cell-specific molecule 1 (ESM1)
  • endothelial cell-specific molecule 1 (esm1)
  • endothelial cell-specific molecule 1 (Esm1)
  • 0610042H23Rik protein
  • AV004503 protein
  • endocan protein
  • ESM-1 protein
  • ESM1 protein
  • Pg25 protein
  • zgc:153027 protein

Protein level used designations for ESM1

endothelial cell-specific molecule 1 , ESM-1 secretory protein , pineal specific PG25 protein , ESM-1

GENE ID SPECIES
462371 Pan troglodytes
705229 Macaca mulatta
767774 Danio rerio
100145234 Xenopus (Silurana) tropicalis
71690 Mus musculus
64536 Rattus norvegicus
11082 Homo sapiens
539571 Bos taurus
489201 Canis lupus familiaris
430807 Gallus gallus
100721245 Cavia porcellus
101117876 Ovis aries
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