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anti-Endothelin Receptor Type A (EDNRA) Antibodies

EDNRA encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. Additionally we are shipping Endothelin-1 Receptor Proteins (16) and Endothelin-1 Receptor Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EDNRA 1909 P25101
EDNRA 24326 P26684
EDNRA 13617 Q61614
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Top anti-Endothelin-1 Receptor Antibodies at

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IF, WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated FACS, IF, WB Flow cytometric analysis of CEM cells using EDNRA Antibody (Center) (green histogram) compared to a negative control cell (blue histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of EDNRA antibody (Center) (ABIN390401) in CEM cell line lysates (35 µg/lane). EDNRA (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
Chicken Rabbit Un-conjugated IHC (p), IHC, WB Immunohistochemistry-Paraffin: EDNRA/Endothelin R Type A Antibody [NBP1-33614] - Paraffin-embedded SW480 xenograft, using antibody at 1:500 dilution. Western Blot: EDNRA/Endothelin R Type A Antibody [NBP1-33614] - Sample (30 ug of whole cell lysate) A: GL261 10% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 5 to 7 Days
REACT_Fly Mouse Un-conjugated WB Western blot analysis of Endothelin Receptor-1. Lysates from rat testis (5 µg/lane), S2 cells (7.5 µg/lane), 0-12 hours Drosophila embryos (7.5 µg/lane) were probed with the mouse anti-endothelin receptor 1 antibody at concentrations of 0.5 µg/ml (lane 1), 0.25 µg/ml (lane 2), and 0.125 µg/ml (lane 3). Endothelin Receptor-1 is detectable at 50-66 kDa. 50 μg Log in to see 5 to 6 Days
REACT_Fly Mouse Un-conjugated IF, WB Western blot analysis of Endothelin 1 Receptor on a rat testis lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the mouse anti-endothelin 1 receptor antibody. Immunofluorescence staining of human endothelial cells. 50 μg Log in to see 5 to 6 Days
Mouse Sheep Un-conjugated ICC, IF, IHC (p), IP, IHC, WB Immunocytochemistry/Immunofluorescence: EDNRA/Endothelin R Type A Antibody [ABIN269861] - EDN 1 Receptor A in 1 MES Cells. Immunofluorescent staining image provided by verified customer review. Western Blot: EDNRA/Endothelin R Type A Antibody [ABIN269861] - ET-1 A & B Receptor Western provided by verified customer review. 0.125 mg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IHC (p) Staining of formalin-fixed, paraffin-embedded human heart with endothelin A receptor 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p) Heart: Formalin-Fixed Paraffin Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated ELISA, IF, WB 100 μL Log in to see 14 Days

EDNRA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Endothelin-1 Receptor Antibodies

  1. Mouse (Murine) Polyclonal Endothelin-1 Receptor Primary Antibody for ICC, IF - ABIN269861 : Meehan, Delimont, Dufek, Zallocchi, Phillips, Gratton, Cosgrove: Endothelin-1 mediated induction of extracellular matrix genes in strial marginal cells underlies strial pathology in Alport mice. in Hearing research 2016 (PubMed)
    Show all 3 references for ABIN269861

  2. Human Polyclonal Endothelin-1 Receptor Primary Antibody for EIA, FACS - ABIN452933 : Cardillo, Schinzari, Melina, Mores, Bosello, Peluso, Zoli, Ferraccioli: Improved endothelial function after endothelin receptor blockade in patients with systemic sclerosis. in Arthritis and rheumatism 2009 (PubMed)
    Show all 2 references for ABIN452933

  3. Cow (Bovine) Polyclonal Endothelin-1 Receptor Primary Antibody for IHC (p), IHC - ABIN443474 : Cook, Brais, Qian, Hak, Corrie: Endothelin-1 and endothelin B receptor expression in pancreatic adenocarcinoma. in Journal of clinical pathology 2015 (PubMed)
    Show all 2 references for ABIN443474

  4. Fly (Calliphora) Monoclonal Endothelin-1 Receptor Primary Antibody for IF, WB - ABIN968439 : Lin, Kaji, Winkel, Ives, Lodish: Cloning and functional expression of a vascular smooth muscle endothelin 1 receptor. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 2 references for ABIN968439

  5. Fly (Calliphora) Monoclonal Endothelin-1 Receptor Primary Antibody for WB - ABIN968897 : Masuda, Miyazaki, Kondoh, Watanabe, Yanagisawa, Masaki, Murakami: Two different forms of endothelin receptors in rat lung. in FEBS letters 1990 (PubMed)
    Show all 2 references for ABIN968897

More Antibodies against Endothelin-1 Receptor Interaction Partners

Horse (Equine) Endothelin Receptor Type A (EDNRA) interaction partners

  1. Hyperinsulinemia caused significant changes in endothelin receptor expression, which suggested that ETR antagonists might be beneficial for treatment of laminitis in horses.

  2. both endothelin A and endothelin B receptors are involved in the net tonic response to ET-1 (show EDN1 Antibodies) in normal laminar veins.

Zebrafish Endothelin Receptor Type A (EDNRA) interaction partners

  1. Data suggest that edn1 (show EDN1 Antibodies)/ednraa (endothelin-1/endothelin-1 (show EDN1 Antibodies) receptor type A) signaling is involved in acid-base regulation and transepithelial proton secretion via vacuolar proton-translocating ATPase (show DNAH8 Antibodies) in zebrafish embryonic skin.

  2. Edn1 (show EDN1 Antibodies) from the pharyngeal ectoderm signals through Ednra proteins to direct early dorsoventral patterning of the skeletogenic neural crest.

Xenopus laevis Endothelin Receptor Type A (EDNRA) interaction partners

  1. A new role for ednra signaling during early neural crest specification is reported.

Human Endothelin Receptor Type A (EDNRA) interaction partners

  1. presence of ET-1 (show EDN1 Antibodies) receptors in the chronic thrombus in proximal CTEPH suggests ET-1 (show EDN1 Antibodies) could act not only on the distal vasculopathy in the unobstructed vessels but may also stimulate smooth muscle cell proliferation within chronic clot (show TXNDC17 Antibodies)

  2. Data show that auriculo-condylar syndrome (ACS (show PLA2G15 Antibodies))-associated mutations in G protein subunit alpha i3 (GNAI3 (show GNAI3 Antibodies)) produce dominant-negative Galpha (show SUCLG1 Antibodies)(i3) mutant proteins that couple to endothelin type A receptor (ET(A)R).

  3. Patients with lung fibrosis and patients with high modified Rodnan skin score showed a reduced endothelin 1 (show EDN1 Antibodies) Type A receptor (ETAR)/ETBR (show EDNRB Antibodies) ratio.

  4. High ETAR expression is associated with ovarian carcinoma.

  5. Data show that macitentan interferes with the profibrotic action of transforming growth factor-beta (TGF-beta), blocking the endothelin receptor type A (ET-1 (show EDN1 Antibodies) receptor) portion of the ET-1 (show EDN1 Antibodies)/TGF-beta (show TGFB1 Antibodies) receptor complex.

  6. Ednra, encoding Endothelin receptor A (ETA)-the target of Endothelin 1 (ET-1 (show EDN1 Antibodies))-was significantly increased in Systemic Capillary Leak Syndrome blood-outgrowth endothelial cells compared to healthy controls.

  7. role of ET-1 (show EDN1 Antibodies)/ETR-A signalling in Gd-induced fibrosis and calcification in nephrogenic systemic fibrosis

  8. Plasma proET-1 levels increase in CKD and may be useful biomarkers of renal injury. Increases in response to endothelin A antagonism may reflect EDN1 (show EDN1 Antibodies) upregulation, which may partly explain fluid retention with these agents.

  9. Genebased analyses revealed associations of the EDNRA gene with longitudinal Blood Pressure phenotypes, associations with essential hypertension, Blood Pressure salt sensitivity, preeclampsia, or preclinical stages of atherosclerosis.

  10. Endothelin receptor A was detected in all patients with squamous cell carcinoma and psoriasis, with a higher frequency and grade of expression than controls and basal cell carcinoma.

Mouse (Murine) Endothelin Receptor Type A (EDNRA) interaction partners

  1. Endothelin A receptor may be involved in paraquat-induced toxic myocardial contractile anomalies possibly related to apoptosis and mitochondrial damage.

  2. OPN (show SPP1 Antibodies) induces oxidative stress via the involvement of mitochondria and NOX-4 (show NOX4 Antibodies). It may affect mitochondrial morphology and integrity, at least in part, via the involvement of BIK (show BIK Antibodies).

  3. Endogenous osteopontin (show SPP1 Antibodies) plays a critical role in the prevention of phosphate-induced nephrocalcinosis and vascular calcification in response to high phosphate load.

  4. GATA4 (show GATA4 Antibodies) acts as a negative regulator of Bsp (show KLK6 Antibodies) expression in osteoblasts.

  5. Genetic deletion of osteopontin (show SPP1 Antibodies) in TRAMP (show DPT Antibodies) mice skews prostate carcinogenesis from adenocarcinoma to aggressive human-like neuroendocrine cancers.

  6. IFN-gamma (show IFNG Antibodies) regulates hypertensive vascular collagen remodeling induced by ANG II (show AGT Antibodies) and inhibits the differentiation of Th17 cells by suppressing OPN (show SPP1 Antibodies) expression and regulating secretion of inflammatory cytokines.

  7. results indicate that autocrine OPN (show SPP1 Antibodies) plays a crucial role in HPC expansion, migration, and subsequent oncogenic transformation of HPCs, which may provide a new insight into hepatocarcinogenesis

  8. OPN (show SPP1 Antibodies) produced by hematogenous macrophages induces astrocyte process extension toward the infarct border zone, which may contribute to repair of the ischemic neurovascular unit following stroke

  9. ETAR-positive macrophages highly accumulated in the inflamed liver of mutant p53 (show TP53 Antibodies)(R172) plus IL27RA (show IL27RA Antibodies)(-/-)

  10. During the priming phase of liver regeneration, osteopontin (show SPP1 Antibodies) enhances the recruitment of macrophages and neutrophils, and triggers hepatocyte proliferation through Kupffer cell-derived IL-6 (show IL6 Antibodies) release and the downstream activation of Stat3 (show STAT3 Antibodies).

Pig (Porcine) Endothelin Receptor Type A (EDNRA) interaction partners

  1. sub-vasomotor concentration of ET-1 (show EDN1 Antibodies) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (show MAPK14 Antibodies) kinase-mediated production of superoxide from NADPH oxidase (show NOX1 Antibodies) following ETA receptor activation

  2. PDE5 (show PDE5A Antibodies) inhibition and increase in cGMP produce pulmonary vasodilation that is mediated in part through inhibition of the ET pathway, thereby precluding an additional vasodilator effect of ETA/ETB (show EDNRB Antibodies) receptor blockade in the presence of PDE5 (show PDE5A Antibodies) inhibition.

  3. Blocking ET(A) and ET(B (show EDNRB Antibodies)) receptors partially protects sinusoidal circulation and tissue oxygenation against stress induced by high intra-abdominal pressure (IAP (show CD47 Antibodies)).

  4. Anti-endothelin receptor A therapy accelerated the reversal of flow-induced pulmonary arterial disease after flow correction.

  5. study suggests a possible role for endothelin-1 (show EDN1 Antibodies)(resulting from the actions of endothelin-converting enzyme-1 (show ECE1 Antibodies)) acting via endothelin receptor A in the control of luteolytic sensitivity in the pig

  6. Endothelin-A receptor antagonist alters the expression of vasoactive genes and proinflammatory cytokines during hepatic ischemic/reperfusion.

  7. Report that inhalation of the endothelin-A receptor antagonist LU-135252 at various doses in experimental acute lung injury improved gas exchange and hemodynamics.

  8. ET(A) blockade had no effect on pulmonary vascular resistance at rest or during exercise.

  9. PKC (show FYN Antibodies) and MAPK (show MAPK1 Antibodies) seem to be involved in the regulation of endothelin type A and type B receptor expression in porcine coronary arteries

Cow (Bovine) Endothelin Receptor Type A (EDNRA) interaction partners

  1. Differential cell-specific and spatiotemporal expression of the EDN1 (show EDN1 Antibodies) system and NOS (show NOS Antibodies) in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.

  2. Elevated local expression of ET-1 (show EDN1 Antibodies) and Ednra/Ednrb (show EDNRB Antibodies) during the peri (show PLIN1 Antibodies)-ovulatory period induces the high contractile activity of the oviduct to optimize gamete transport.

Endothelin-1 Receptor (EDNRA) Antigen Profile

Protein Summary

This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with EDNRA

  • endothelin receptor type A (EDNRA) antibody
  • endothelin receptor type Aa (ednraa) antibody
  • endothelin receptor type A (ednra-a) antibody
  • endothelin receptor type A (ednra) antibody
  • endothelin receptor type A (etr) antibody
  • endothelin receptor type A (Ednra) antibody
  • secreted phosphoprotein 1 (Spp1) antibody
  • 2AR antibody
  • Apl-1 antibody
  • BNSP antibody
  • Bsp antibody
  • BSPI antibody
  • ednr-a antibody
  • ednra antibody
  • ednraa antibody
  • Endor antibody
  • ET-A antibody
  • ET-AR antibody
  • ETa antibody
  • ETA-1 antibody
  • ETA-R antibody
  • ETAR antibody
  • ETRA antibody
  • Gpcr10 antibody
  • hET-AR antibody
  • OP antibody
  • Opn antibody
  • Opnl antibody
  • RGD1559432 antibody
  • Ric antibody
  • Spp-1 antibody
  • wu:fb75g12 antibody

Protein level used designations for EDNRA

endothelin-1 receptor , Ednra2 , endothelin receptor A , endothelin receptor type A , endothelin type-A receptor 2 , etID40953.1 , Endothelin-1 receptor type A , endothelin receptor type A a , G protein-coupled receptor , endothelin receptor subtype A , endothelin-1-specific receptor , endothelin A receptor , ET-A , G-protein coupled receptor 10 , ET-AR , 44 kDa bone phosphoprotein , bone sialoprotein 1 , calcium oxalate crystal growth inhibitor protein , early T-lymphocyte activation 1 protein , minopontin , osteopontin , osteopontin-like protein

100062644 Equus caballus
114550 Danio rerio
380342 Xenopus laevis
779728 Xenopus (Silurana) tropicalis
100049646 Takifugu rubripes
1909 Homo sapiens
24326 Rattus norvegicus
13617 Mus musculus
373908 Gallus gallus
450187 Canis lupus familiaris
397457 Sus scrofa
281749 Bos taurus
443465 Ovis aries
20750 Mus musculus
Selected quality suppliers for anti-Endothelin-1 Receptor (EDNRA) Antibodies
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