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anti-Engrailed Homeobox 2 (EN2) Antibodies

Homeobox-containing genes are thought to have a role in controlling development. Additionally we are shipping EN2 Kits (14) and EN2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EN2 13799 P09066
EN2 2020 P19622
EN2 499964  
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Top anti-EN2 Antibodies at antibodies-online.com

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-EN2 Antibody Titration: 0.05ug/mlELISA Titer: 1:2500Positive Control: Human cerebellum 100 μL Log in to see 2 to 3 Days
$289.00
Details
Rat Goat Un-conjugated ELISA, WB EB07120 (0.1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of EN2 antibody (C-term) in 293 cell line lysates and mouse stomach and lung tissue lysates (35ug/lane). EN2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of EN2 antibody (C-term) (ABIN391665) in 293 cell line lysates and mouse stomach and lung tissue lysates (35 µg/lane). EN2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of EN2 antibody (C-term-2) (ABIN391666) in NCI-H460 cell line lysates (35 µg/lane). EN2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain with EN2 Antibody (C-term-2), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with EN2 antibody ABIN462164 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of EN2 Antibody (C-term) (ABIN652344) in mouse cerebellum, brain tissue lysates (35 µg/lane). EN2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with EN2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

EN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EN2 Antibodies

  1. Human Polyclonal EN2 Primary Antibody for EIA, WB - ABIN359621 : Poole, Law, Kao, Lau: Isolation and chromosomal localization of the human En-2 gene. in Genomics 1989 (PubMed)
    Show all 2 references for ABIN359621

  2. Human Polyclonal EN2 Primary Antibody for IHC, WB - ABIN2777264 : Zhong, Serajee, Nabi, Huq: No association between the EN2 gene and autistic disorder. in Journal of medical genetics 2003 (PubMed)

  3. Dog (Canine) Polyclonal EN2 Primary Antibody for WB - ABIN374650 : Benayed, Gharani, Rossman, Mancuso, Lazar, Kamdar, Bruse, Tischfield, Smith, Zimmerman, Dicicco-Bloom, Brzustowicz, Millonig: Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus. in American journal of human genetics 2005 (PubMed)

More Antibodies against EN2 Interaction Partners

Mouse (Murine) Engrailed Homeobox 2 (EN2) interaction partners

  1. En2 deletion reduces monoamine innervation of target forebrain structures, affecting forebrain structural growth, postnatal neurogenesis and related behavior.

  2. confirm the early neurotransmitter deficit with a late compensatory recovery in En2 KO-mice further suggesting that this experimental animal may be considered a good predictive model for the human disease

  3. The homeoprotein Engrailed is not only a survival factor for mesencephalic dopaminergic (mDA) neurons during development, but continues to exert neuroprotective and physiological functions in adult mDA neurons. [Review]

  4. En2-/- hippocampus, neurofibromin (show NF1 Antibodies)-dependent pathways converging on SynI (show SYN1 Antibodies) phosphorylation might underlie hippocampal-dependent learning deficits observed in En2-/- mice.

  5. This study demonistrated that engrailed 2 knock-out mice show impaired spatial learning with hippocampal dysreulation.

  6. EN2 levels are increased in affected individuals with an A-C/G-T genotype, supporting EN2 as an autism spectrum disorder susceptibility gene.

  7. This study showed that the Engrailed proteins are present in postnatal GABAergic neurons of the mouse hippocampus and cerebral cortex, and adult En2(-/-) mice show reduced expression of GABAergic marker mRNAs in these areas.

  8. En1 (show EN1 Antibodies) is the predominant functional En paralog in maturing 5-HT (show DDC Antibodies) neurons, although a small contribution from En2 was reproducibly detected

  9. En1 (show EN1 Antibodies) and En2 act together in multiple cerebellar cell types to determine overall growth and formation of particular fissures.

  10. This study characterized En1 (show EN1 Antibodies) and En2 expression around birth and at postnatal day (P) 21 during the period when the cerebellum undergoes a remarkable transformation from a smooth ovoid structure to a highly foliated structure.

Human Engrailed Homeobox 2 (EN2) interaction partners

  1. EN2 may be a candidate oncogene (show RAB1A Antibodies) in bladder cancer by activating the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway and inhibiting PTEN (show PTEN Antibodies).

  2. Engrailed-2 (EN-2) is a developmentally regulated homeobox (show Lbx1 Antibodies) gene that is essential for Purkinje cell maturation and normal cerebellar development and patterning.

  3. The mean EN2 levels in prostate cancer patients were 3.76-fold higher than those in non-prostate patients after prostate massage.

  4. The exact role of EN2 expression in renal carcinoma (show TSC2 Antibodies) carcinogenesis requires further investigation.

  5. En2 identified as a new regulator of T-cell differentiation whose disruption induces a malignant T-cell fate in chronic myelogenous leukemia progression.

  6. Two patients with underdeveloped arcuate fasciculus had novel, nonsynonymous variants in MID1 (show MID1 Antibodies) and EN2 genes regulating axon guidance pathway.

  7. EN2 levels are increased in affected individuals with an A-C/G-T genotype, supporting EN2 as an autism spectrum disorder susceptibility gene.

  8. urinary EN2 has the potential to be a more sensitive and specific protein biomarker for non-muscle-invasive bladder cancer than currently available tests.

  9. Urinary EN2 may be useful as a non-invasive early biomarker for prostate cancer detection in genetically high-risk individuals

  10. Normal EN-2 downregulation may not occur in some individuals with autism, such that the postnatal persistence of EN-2 overexpression may contribute to autism cerebellar abnormalities.

EN2 Antigen Profile

Protein Summary

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Gene names and symbols associated with EN2

  • engrailed homeobox 2 (EN2) antibody
  • engrailed homeobox (en) antibody
  • engrailed 2 (En2) antibody
  • engrailed homeobox 2 (En2) antibody
  • engrailed homeobox 2 (LOC100859435) antibody
  • BB131122 antibody
  • en antibody
  • En-2 antibody
  • en2 antibody
  • Gg-En-2 antibody
  • RGD1561842 antibody

Protein level used designations for EN2

engrailed homeobox 2 , engrailed 2 , engrailed homolog 2 , engrailed homeobox , homeobox protein en-2 , homeobox protein engrailed-2 , mo-En-2 , engrailed-2 , hu-En-2

GENE ID SPECIES
280783 Bos taurus
716307 Macaca mulatta
742707 Pan troglodytes
100303466 Saccoglossus kowalevskii
13799 Mus musculus
2020 Homo sapiens
499964 Rattus norvegicus
100859435 Gallus gallus
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