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Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) Proteins (EDC3)

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008].. Additionally we are shipping EDC3 Antibodies (54) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat EDC3 EDC3 315708  
EDC3 80153 Q96F86
EDC3 353190 Q8K2D3
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Top EDC3 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 56 to 66 Days
$3,274.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EDC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) Interaction Partners

Fruit Fly (Drosophila melanogaster) Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) interaction partners

  1. The modular architecture enables enhancer of decapping 3 (EDC3) to interact with multiple components of the decapping (show ACE Proteins) machi (show DCP2 Proteins)nery, inclu (show DDX6 Proteins)ding DCP1, DCP2, and Me31B.

  2. Tral (show LSM14A Proteins) and EDC3 specifically interact with the decapping activator DCP1 (show ACE Proteins) and the DEAD-box helicase Me31B (show DDX6 Proteins), in Drosophila cells.

Human Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) interaction partners

  1. In vitro decapping assays showed that altered EDC3 is unable to enhance DCP2 (show DCP2 Proteins) decapping at low concentrations and even inhibits DCP2 (show DCP2 Proteins) decapping at high concentration.

  2. The modular architecture enables EDC3 to interact with multiple components of the decapping machinery, including DCP1 (show ACE Proteins), DCP2 (show DCP2 Proteins), and Me31B (show DDX6 Proteins).

  3. The dimerization interface of Edc3 is highly conserved in eukaryotes despite the overall low sequence homology across species; structure-based site-directed mutagenesis revealed dimerization is required for efficient RNA binding, P-body formation

  4. Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral (show LSM14A Proteins) to the DEAD box protein (show INTS6 Proteins) DDX6/Me31B (show DDX6 Proteins).

Mouse (Murine) Enhancer of MRNA Decapping 3 Homolog (S. Cerevisiae) (EDC3) interaction partners

  1. Induction of 14-3-3 (show YWHAQ Proteins) binding to EDC3 causes morphological changes in processing body structures, inhibition of microRNA-mediated mRNA post-transcriptional regulation, and alterations in the protein- protein interactions of EDC3.

EDC3 Protein Profile

Protein Summary

EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005

Gene names and symbols associated with EDC3

  • enhancer of mRNA decapping 3 homolog (S. cerevisiae) (Edc3)
  • Enhancer of decapping 3 (Edc3)
  • enhancer of mRNA decapping 3 (edc3)
  • enhancer of mRNA decapping 3 homolog (S. cerevisiae) (EDC3)
  • enhancer of mRNA decapping 3 (EDC3)
  • enhancer of mRNA decapping 3 homolog (S. cerevisiae) (edc3)
  • AA517853 protein
  • CG6311 protein
  • DmEDC3 protein
  • Dmel\\CG6311 protein
  • EDC3 protein
  • im:7151288 protein
  • lsm16 protein
  • RGD1306898 protein
  • wu:fb82d07 protein
  • Yjdc protein
  • YJEFN2 protein
  • zgc:112006 protein

Protein level used designations for EDC3

LSM16 homolog (EDC3, S. cerevisiae) , CG6311-PB , Edc3-PB , enhancer of decapping 3 , enhancer of decapping-3 , enhancer of mRNA decapping 3 homolog , enhancer of mRNA-decapping protein 3 , yjeF domain-containing protein 1 , hYjeF_N2 , hYjeF_N2-15q23 , yjeF N-terminal domain-containing protein 2 , yjeF domain containing , yjeF_N2 , LSM16 protein homolog

GENE ID SPECIES
315708 Rattus norvegicus
39957 Drosophila melanogaster
495065 Xenopus laevis
100171859 Pongo abelii
80153 Homo sapiens
353190 Mus musculus
415294 Gallus gallus
504054 Danio rerio
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