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Enhancer of MRNA Decapping 4 Proteins (EDC4)

In the process of mRNA degradation, seems to play a role in mRNA decapping (By similarity). Additionally we are shipping EDC4 Antibodies (33) and EDC4 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EDC4 23644 Q6P2E9
EDC4 234699 Q3UJB9
Rat EDC4 EDC4 361399 Q3ZAV8
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Top EDC4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

EDC4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Enhancer of MRNA Decapping 4 (EDC4) Interaction Partners

Arabidopsis thaliana Enhancer of MRNA Decapping 4 (EDC4) interaction partners

  1. Seedling lethal phenotypes in dcp1 (show ACE Proteins), dcp2 (show DCP2 Proteins) and vcs mutants are caused the disruption of miRNA-mediated gene regulation.

  2. DCP2 (show DCP2 Proteins) interacts in vitro and in vivo with DCP1 (show ACE Proteins) and VARICOSE (VCS), an Arabidopsis homolog of human Hedls/Ge-1, suggesting that the three proteins operate as a decapping complex.

Human Enhancer of MRNA Decapping 4 (EDC4) interaction partners

  1. The assembly of EDC4 and Dcp1a (show DCP1A Proteins) into processing bodies is critical for the translational regulation of IL-6 (show IL6 Proteins).

  2. LMKB is the first protein identified to date that interacts with this portion of Ge-1. LMKB was expressed in human B and T lymphocyte cell lines; depletion of LMKB increased expression of IFI44L (show IFI44L Proteins).

  3. EDC4 is a processing body (P-body) component.

  4. The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells.

  5. EDC4 might contribute to regulation of CoA biosynthesis in addition to its scaffold function in processing bodies

Mouse (Murine) Enhancer of MRNA Decapping 4 (EDC4) interaction partners

  1. Ge-1, the human ortholog of mouse Edc4, was shown to localize to mRNA processing bodies (P-body)in a human cell line. The C-terminal region is required for this localization.

  2. The human Ge-1 gene (also known as Hedls and Edc4)is an ortholog of mouse Edc4. The gene was identified by screening a cDNA expression library using serum from a patient with Sjogren's syndrome.

EDC4 Protein Profile

Protein Summary

In the process of mRNA degradation, seems to play a role in mRNA decapping (By similarity).

Gene names and symbols associated with EDC4

  • enhancer of mRNA decapping 4 (EDC4)
  • mRNA decapping complex VCS (VCS)
  • enhancer of mRNA decapping 4 (edc4)
  • enhancer of mRNA decapping 4 (Edc4)
  • BC022641 protein
  • Ge-1 protein
  • GE1 protein
  • HEDL5 protein
  • HEDLS protein
  • LRRG00115 protein
  • Nrn1l protein
  • RCD-8 protein
  • RCD8 protein
  • RGD1309136 protein
  • si:ch211-237c7.1 protein
  • VARICOSE protein
  • wu:fe26b05 protein

Protein level used designations for EDC4

enhancer of mRNA decapping 4 , autoantigen Ge-1 , autoantigen RCD-8 , enhancer of mRNA-decapping protein 4 , human enhancer of decapping large subunit , autoantigen RCD8 , fe26b05

GENE ID SPECIES
415656 Gallus gallus
454178 Pan troglodytes
820530 Arabidopsis thaliana
100379843 Xenopus (Silurana) tropicalis
23644 Homo sapiens
234699 Mus musculus
565659 Danio rerio
379239 Xenopus laevis
489751 Canis lupus familiaris
513171 Bos taurus
361399 Rattus norvegicus
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