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Enhancer of Polycomb Homolog 1 (Drosophila) Proteins (EPC1)

EPC1 encodes a member of the polycomb group (PcG) family. Additionally we are shipping EPC1 Antibodies (17) and EPC1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat EPC1 EPC1 307042  
EPC1 80314 Q9H2F5
EPC1 13831 Q8C9X6
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Top EPC1 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

EPC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Enhancer of Polycomb Homolog 1 (Drosophila) (EPC1) Interaction Partners

Human Enhancer of Polycomb Homolog 1 (Drosophila) (EPC1) interaction partners

  1. Epigenetic factor EPC1 (show SERPINF1 Proteins) is a master regulator of DNA damage response by interacting with E2F1 (show E2F1 Proteins) to silence death and activate metastasis-related gene signatures

  2. Silencing EPC1 (show SERPINF1 Proteins) by short hairpin RNA technology had the inhibition effects on cell proliferation and tumor growth in lung cancer

  3. EPC1 (show SERPINF1 Proteins) and EPC2 are components of a complex that directly or indirectly serves to prevent MYC (show MYC Proteins) accumulation and AML (show RUNX1 Proteins) cell apoptosis, thus sustaining oncogenic potential

  4. Epc1 (show SERPINF1 Proteins) plays a role in the initiation of skeletal muscle differentiation, and its interaction with Hop (show STIP1 Proteins) is required for the full activity.

  5. SNP array CGH analysis of the breakpoint region in 3 ATLL-related cell lines and 4 patient samples revealed the chromosomal breakpoints are localized within the EPC1 (show SERPINF1 Proteins) gene locus in an ATLL-derived cell line (SO4) and in one patient with acute-type ATLL.

Mouse (Murine) Enhancer of Polycomb Homolog 1 (Drosophila) (EPC1) interaction partners

  1. results indicate that Epc1 induces vascular smooth muscle differentiation by interacting with myocardin to induce serum response factor-dependent smooth muscle genes; propose that Epc1 acts as a novel negative regulator of neointima formation after carotid injury

  2. Epc1-induced enhancements of SRF-dependent multinucleation, transactivation of the skeletal alpha-actin (show ACTA1 Proteins) promoter, binding of SRF to the serum response element, and muscle-specific (show EIF3K Proteins) gene induction were blocked by RFP (show RFP Proteins).

  3. showed that E2F6 (show E2F6 Proteins), DP1 (show REEP5 Proteins), EPC1, EZH2 (show EZH2 Proteins), and Sin3B (show SIN3B Proteins) co-elute, suggesting the identification of a novel E2F6 (show E2F6 Proteins) complex that exists in vivo in both normal and transformed human cell lines

  4. Epc1 plays a role in the initiation of skeletal muscle differentiation, and its interaction with Hop (show STIP1 Proteins) is required for the full activity.

  5. Epc1 is required for skeletal muscle differentiation by recruiting both SRF and p300 (show NOTCH1 Proteins) to the SRE of muscle-specific (show EIF3K Proteins) gene promoters

EPC1 Protein Profile

Protein Summary

This gene encodes a member of the polycomb group (PcG) family. The encoded protein is a component of the NuA4 histone acetyltransferase complex and can act as both a transcriptional activator and repressor. The encoded protein has been linked to apoptosis, DNA repair, skeletal muscle differentiation, gene silencing, and adult T-cell leukemia/lymphoma. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with EPC1

  • enhancer of polycomb homolog 1 (Drosophila) (EPC1)
  • enhancer of polycomb homolog 1 (Drosophila) (epc1)
  • enhancer of polycomb homolog 1 (Drosophila) (Epc1)
  • 2400007E14Rik protein
  • 5730566F07Rik protein
  • A930032N02Rik protein
  • EPC1 protein
  • Epl1 protein

Protein level used designations for EPC1

enhancer of polycomb homolog 1 (Drosophila) , enhancer of polycomb 1 , enhancer of polycomb homolog 1 , enhancer of polycomb homolog 1-like

GENE ID SPECIES
450393 Pan troglodytes
566686 Danio rerio
307042 Rattus norvegicus
100018378 Monodelphis domestica
100060812 Equus caballus
100353948 Oryctolagus cuniculus
100391598 Callithrix jacchus
100456870 Pongo abelii
100473445 Ailuropoda melanoleuca
100562289 Anolis carolinensis
80314 Homo sapiens
420471 Gallus gallus
477970 Canis lupus familiaris
448975 Sus scrofa
534386 Bos taurus
13831 Mus musculus
100362678 Rattus norvegicus
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