anti-Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) Antibodies

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009].. Additionally we are shipping EZH1 Kits (8) and EZH1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EZH1 2145 Q92800
EZH1 14055 P70351
EZH1 303547  
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Top anti-EZH1 Antibodies at antibodies-online.com

Showing 10 out of 104 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated ChIP, WB Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-EZH1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>COLO205 cell lysate Immunohistochemistry with Spleen tissue at an antibody concentration of 5µg/ml using anti-EZH1 antibody (ARP38092_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-EZH1 Antibody (Center) (ABIN389082) in 293 cell line lysates (35 µg/lane). EZH1(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HT-29/LOVO/A549/NIH-3T3/RAW264.7/COS7 cells, using EZH1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using EZH1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB ABIN184879 staining (2µg/ml) of MOLT-4 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated WB Western Blot: EZH1 Antibody [ABIN43098228] - Detection of EZH1 in mouse (lane 1) and human (lane 2) spleen lysate using this antibody at 2 ug/ml. Western Blot: EZH1 Antibody [ABIN43098228] - WB detection of EZH1 protein in (A ) Ramos cells lysate, (B) Daudi cells lysate and (C) Peptide blocked - Daudi cells lysate by using EZH1 antibody at a concentration of 2 ug/ml. 0.1 mg Log in to see 7 to 9 Days
$447.56
Details
Bat Rabbit Un-conjugated IHC (p), WB Anti-EZH1 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958979 concentration 5 ug/ml. 50 μg Log in to see 7 to 9 Days
$676.50
Details
Cow Goat Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$507.83
Details

EZH1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EZH1 Antibodies

  1. Human Polyclonal EZH1 Primary Antibody for ELISA, WB - ABIN249717 : Abel, Brody, Valdes, Erdos, McKinley, Castilla, Merajver, Couch, Friedman, Ostermeyer, Lynch, King, Welcsh, Osborne-Lawrence, Spillman, Bowcock, Collins, Weber: Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1. in Genomics 1997 (PubMed)

  2. Human Polyclonal EZH1 Primary Antibody for WB - ABIN4309822 : Grimaldi, Christian, Steel, Henriet, Poutanen, Brosens: Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells. in Molecular endocrinology (Baltimore, Md.) 2011 (PubMed)

More Antibodies against EZH1 Interaction Partners

Human Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) interaction partners

  1. Expression of the EZH2 (show EZH2 Antibodies) homolog EZH1 is reduced in EZH2 (show EZH2 Antibodies)-deficient CML (show BCR Antibodies) LICs, creating a scenario resembling complete loss of PRC2. EZH2 (show EZH2 Antibodies) dependence of CML (show BCR Antibodies) LICs raises prospects for improved therapy of TKI-resistant CML (show BCR Antibodies) and/or eradication of disease by addition of EZH2 (show EZH2 Antibodies) inhibitors

  2. a hot-spot mutation in EZH1 is the second most frequent genetic alteration in autonomous thyroid adenomas; the association between EZH1 and TSHR (show TSHR Antibodies) mutations suggests a 2-hit model for the pathogenesis of these tumors, whereby constitutive activation of the cAMP pathway and EZH1 mutations cooperate to induce the hyperproliferation of thyroid cells

  3. EZH1, SUZ12 (show SUZ12 Antibodies) and UXT (show UXT Antibodies) work synergistically to regulate pathway activation in the nucleus.

  4. The authors report a novel PRC2-Ezh1 function that utilizes Ezh1beta as an adaptive stress sensor in the cytoplasm, thus allowing postmitotic cells to maintain tissue integrity in response to environmental changes.

  5. These evidences suggest that EZH2 (show EZH2 Antibodies) and EZH1 are important in the counter-balancing mechanisms controlling proliferation/resting of lymphoid cells. The disruption of the balanced EZH2/EZH1 (show EZH2 Antibodies) ratio may play important roles in the pathogenesis of lymphomas

  6. The related enzymatic subunits EZH1 and EZH2 (show EZH2 Antibodies) undergo an expression switch during blood cell development.

  7. EZH1 maintains repressive chromatin through different mechanisms.

Mouse (Murine) Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) interaction partners

  1. Ezh1 is required for neonatal heart regeneration and development.

  2. in the skin epithelium, EED (show EED Antibodies), Suz12 (show SUZ12 Antibodies), and Ezh1/2 function largely as subunits of the PRC2 complex and have roles in skin development

  3. the expression level of Ezh1 determines the restoration of H3K27 methylation in the absence of the canonical EZH2 (show EZH2 Antibodies)-PRC2.

  4. These results clearly demonstrated an essential role of Ezh1 in the pathogenesis of hematopoietic malignancies induced by Ezh2 (show EZH2 Antibodies) insufficiency, and highlighted the differential functions of Ezh1 and Ezh2 (show EZH2 Antibodies) in hematopoiesis.

  5. Loss of EZH1 is associated with increased liver injury and a blunted regenerative response.

  6. Data show that histone lysine methyltransferase Ezh1 promotes toll (show TLR4 Antibodies)-like receptor (TLR)-triggered inflammatory cytokine production by suppressing the Toll-interacting protein (Tollip (show TOLLIP Antibodies)), contributing to full activation of the innate immunity.

  7. presence of Ezh1 helps to maintain PRC2 occupancy on its target genes in myoblasts where Jarid2 (show JARID2 Antibodies) is not expressed.

  8. Deletion of Ezh1 and Ezh2 (show EZH2 Antibodies) from skin results in a marked change in fate determination in epidermal progenitor cells, leading to an increase in the number of lineage-committed Merkel cells, specialized subtype of skin cells involved in mechanotransduction.

  9. Ezh1 is an important histone methyltransferase for hematopietic stem cell maintenance.

  10. Ezh1 has a role in promoting mRNA transcription.

Xenopus laevis Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) interaction partners

  1. Study shows that the PRC2 core components are enriched in retinal progenitors and downregulated in differentiated cells. Knockdown of the PRC2 core component Ezh2 (show EZH2 Antibodies) leads to reduced retinal progenitor proliferation.

EZH1 Antigen Profile

Protein Summary

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008

Gene names and symbols associated with EZH1

  • enhancer of zeste homolog 1 (Drosophila) (EZH1) antibody
  • enhancer of zeste homolog 1 (Drosophila) (LOC100221384) antibody
  • enhancer of zeste homolog 1 (Drosophila) (ezh1) antibody
  • enhancer of zeste homolog 1 (Drosophila) (Ezh1) antibody
  • enhancer of zeste homolog 2 (ezh2-a) antibody
  • AW557915 antibody
  • enx-1 antibody
  • enx1 antibody
  • ezh1 antibody
  • ezh2 antibody
  • kmt6 antibody
  • KMT6B antibody
  • mKIAA0388 antibody
  • si:ch211-250i3.1 antibody
  • xez antibody
  • zgc:136829 antibody

Protein level used designations for EZH1

enhancer of zeste homolog 1 (Drosophila) , enhancer of zeste homolog 1-like , histone-lysine N-methyltransferase EZH1-like , ENX-2 , histone-lysine N-methyltransferase EZH1 , enhancer of zeste 1 , enhancer of zeste homolog 1 , Enhancer of zeste homolog 2-A , Polycomb protein EZH2-A , histone-lysine N-methyltransferase EZH2

GENE ID SPECIES
454697 Pan troglodytes
100052411 Equus caballus
100221384 Taeniopygia guttata
100351852 Oryctolagus cuniculus
100411881 Callithrix jacchus
100547448 Meleagris gallopavo
100559669 Anolis carolinensis
100604860 Nomascus leucogenys
2145 Homo sapiens
14055 Mus musculus
533087 Bos taurus
303547 Rattus norvegicus
664754 Danio rerio
420023 Gallus gallus
480516 Canis lupus familiaris
100518394 Sus scrofa
100720693 Cavia porcellus
399174 Xenopus laevis
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