Eosinophil Peroxidase Proteins (EPX)

EPX is a member of the peroxidase gene family and is expressed in eosinophils. Additionally we are shipping EPX Antibodies (71) and EPX Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EPX 8288 P11678
EPX 13861 P49290
Rat EPX EPX 303414  
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Top EPX Proteins at antibodies-online.com

Showing 7 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Human Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$755.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details
HOST_Human Human Un-conjugated   200 μg Log in to see 2 to 3 Days
$1,258.40
Details

EPX Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine) ,

More Proteins for Eosinophil Peroxidase (EPX) Interaction Partners

Xenopus laevis Eosinophil Peroxidase (EPX) interaction partners

  1. tyrosine phosphorylation of PMR1 (show ATP2C1 Proteins) is required for the targeting and degradation of polyribosome-bound substrate mRNA

Human Eosinophil Peroxidase (EPX) interaction partners

  1. Both MPO (show MPO Proteins) and EPO (show EPO Proteins) are causatively involved in breast cancer progression and identified as potential therapeutic targets whereby specific novel inhibitors may reduce tumor growth and limit the occurrence of metastasis.

  2. The main significance of this work is the discovery of EPO (show EPO Proteins) as a novel ligand for the HER2 (show ERBB2 Proteins) receptor. Following HER2 (show ERBB2 Proteins) activation, EPO (show EPO Proteins) induces activation of FAK (show PTK2 Proteins) and subsequent activation of beta1-integrin, via inside-out signaling. This complex results in downstream activation of ERK1/2 and a sustained up regulation of both MUC4 (show MUC4 Proteins) and the HER2 (show ERBB2 Proteins) receptor

  3. EPO (show EPO Proteins)-mediated protein carbamylation is promoted during allergen-induced asthma exacerbation, and can both modulate immune responses and trigger a cascade of many of the inflammatory signals present in asthma.

  4. there is a strong association in a given patient between both nasal and pharyngeal EPX levels and the eosinophil percentage of induced sputum.

  5. Myeloperoxidase (show MPO Proteins) and eosinophil peroxidase are readily internalized by HUVEC cells where they promote cellular proliferation, migration, invasion, and stimulate angiogenesis both in vitro and in vivo.

  6. A preferential role of EPO (show EPO Proteins) signaling via a specific surface receptor that leads to neural plasticity.

  7. Eosinophil peroxidase in sputum represents a unique biomarker of airway eosinophilia.

  8. report the prevalence of a common SNP in the eosinophil protein x/eosinophil-derived neurotoxin (show RNASE2 Proteins) (EPX/EDN (show RNASE2 Proteins), RNase2 (show RNASE2 Proteins)) and the association with the cellular contents of EPX/EDN (show RNASE2 Proteins) and ECP (show ECP Proteins)

  9. Polymorphisms of EPX and ECP (show ECP Proteins) are associated to inflammatory bowel disease in an age and gender dependent manne.

  10. Data indicate that eosinophil peroxidase (EPX)-based ELISA is the only eosinophil-specific assay.

Mouse (Murine) Eosinophil Peroxidase (EPX) interaction partners

  1. EPO (show EPO Proteins)-mediated protein carbamylation is promoted during allergen-induced asthma exacerbation, and can both modulate immune responses and trigger a cascade of many of the inflammatory signals present in asthma.

  2. The absence of MBP-1 (show ENO1 Proteins) and EPX promoted a concomitant loss of eosinophil lineage-committed progenitors in the marrow, identifying a specific blockade in eosinophilopoiesis as the causative event.

  3. HER2 (show ERBB2 Proteins) was identified as a novel mediator of eosinophil peroxidase signaling. Eosinophil peroxidase, at noncytotoxic levels, can drive cell-cycle progression and proliferation.

  4. Host protection against Brugia pahangi infections was unimpaired in mice deficient in eosinophil peroxidase.

  5. Mice deficient for either eosinophil peroxidase or major basic protein on the 129/SvJ background developed significantly higher worm burdens than wild-type mice.

  6. post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase

  7. The activities of EPO (show EPO Proteins), an eosinophilic secondary granule protein, do not affect the development of allergic pulmonary pathologies in the mouse lung at levels comparable to those observed in humans with asthma.

EPX Protein Profile

Protein Summary

This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.

Gene names and symbols associated with Eosinophil Peroxidase Proteins (EPX)

  • eosinophil peroxidase (EPX)
  • eosinophil peroxidase (epx)
  • eosinophil peroxidase (Epx)
  • EPO protein
  • EPP protein
  • EPX protein
  • EPX-PEN protein
  • pmr-1 protein

Protein level used designations for Eosinophil Peroxidase Proteins (EPX)

eosinophil peroxidase , polysomal ribonuclease 1 , eosinophil peroxidase-like

GENE ID SPECIES
788751 Bos taurus
468420 Pan troglodytes
491109 Canis lupus familiaris
709655 Macaca mulatta
398084 Xenopus laevis
100437241 Pongo abelii
100473148 Ailuropoda melanoleuca
8288 Homo sapiens
13861 Mus musculus
303414 Rattus norvegicus
100514365 Sus scrofa
Selected quality suppliers for EPX Proteins (EPX)
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