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EPHA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Additionally we are shipping Ephrin Type A Receptor 1 Antibodies (144) and Ephrin Type A Receptor 1 Kits (22) and many more products for this protein.
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Mouse (Murine) EPHA1 Protein expressed in Human Cells - ABIN2008350
Flanagan, Vanderhaeghen: The ephrins and Eph receptors in neural development. in Annual review of neuroscience 1998
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Results show that EPHA1 expression is up-regulated in ovarian cancer (OC) cells and provide evidence that it may promote the aggression of some OC cells.
EPHA1 suppresses spreading and adhesion of HRT18 colorectal cancer cells through deactivation of ERK (show EPHB2 Proteins) and JNK (show MAPK8 Proteins) signaling pathways.
Data indicate that EphA1 protein may be a new marker for the prognosis of clear cell renal cell carcinoma (show MOK Proteins).
High expression of EphA1 was associated with metastasis and recurrence in Gastric Cancer.
This study suggests EPHA1 (rs11771145) interferes with the pathological alteration of the hippocampus and the lateral occipitotemporal and inferior temporal gyri throughout the Alzheimer's disease process, leading to a lower risk of Alzheimer's disease.
EphrinA1 plays an important role in the TNF-alpha (show TNF Proteins)-mediated adhesion of monocytes to endothelial cells.
Lack of ephrin receptor A1 is a favorable independent prognostic factor in clear cell renal cell carcinoma (show MOK Proteins).
two states of the EphA1 transmembrane helix dimer
Suggest EphA1 receptor may have roles in carcinogenesis and progression of prostate cancer.
High Eph A1 expression is associated with choriocarcinoma invasion.
Activation of EphA1-Epha receptor axis attenuates diabetic nephropathy in mice.
These findings suggest that the ternary complex of EphA, FGFR (show FGFR2 Proteins) and FRS2alpha (show FRS2 Proteins) formed by ligand stimulation regulates self-renewal and differentiation of mouse embryonic neural stem/progenitor cells
Whole-mount in situ hybridization revealed overlapping expression of the Epha1 receptor and its high-affinity ligands ephrin A1 (Efna1 (show EFNA1 Proteins)) and ephrin A3 (Efna3 (show EFNA3 Proteins)) in the primitive streak and the posterior paraxial mesoderm during early mouse development.
expression of Eph A1, A2, A4, and A7 was strongly detected in endometrial epithelial cells during early pregnancy.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
eph tyrosine kinase 1
, ephrin type-A receptor 1
, erythropoietin-producing hepatoma amplified sequence
, erythropoietin-producing hepatoma receptor
, oncogene EPH
, soluble EPHA1 variant 1
, soluble EPHA1 variant 2
, tyrosine-protein kinase receptor EPH
, embryonic stem cell kinase
, tyrosine-protein kinase receptor ESK
, ephrin receptor EphA1
, protein tyrosine kinase EphA9