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Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. Additionally we are shipping Epiphycan Antibodies (35) and Epiphycan Kits (14) and many more products for this protein.
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Epyc is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
Linkage and haplotype analyses identified 12q21.33 as a locus for posterior amorphous corneal dystrophy. However, no mutations were identified in the candidate genes (KERA (show KERA Proteins), LUM (show LUM Proteins), DCN (show DCN Proteins), EPYC) within this region.
In addition, no pathogenic sequence variations were found in DCN (show DCN Proteins), DSPG3, LUM (show LUM Proteins), PITX2 (show PITX2 Proteins) and FOXC1 (show FOXC1 Proteins), which have also been implicated in corneal and anterior segment dysgenesis.
OPTC (show OPTC Proteins) and EPYC are unlikely to play a major role in high myopia.
Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins.
, dermatan sulfate proteoglycan 3
, dermatan sulphate proteoglycan 3
, small chondroitin/dermatan sulfate proteoglycan
, epiphycan proteoglycan
, proteoglycan core protein