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Probably involved in cell proliferation and cell-cell interactions.. Additionally we are shipping EMP3 Kits (6) and EMP3 Proteins (6) and many more products for this protein.
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Independent validation with glioma patients tissue (n = 70) and normal brain tissue (n = 19) found PPIC (show PPIC Antibodies), EMP3 and CHI3L1 (show CHI3L1 Antibodies) were up-regulated in glioma tissue. Survival value validation showed that the three genes correlated with patient survival by Kaplan-Meir analysis, including grades, age and therapy.
The study provided a new insight into EMP3, suggesting that EMP3 enhances malignancy of hepatocellular carcinoma cells
EMP3 functions as an oncogene (show RAB1A Antibodies) and is regulated by microRNA-765 in primary breast carcinoma.
The aim of this study was to investigate the EMP3 promoter hypermethylation status in a series of 229 astrocytic and oligodendroglial tumors and in 16 glioblastoma cell lines.
Decreased expression of EMP3 by promoter methylation is associated by lung cancer
LOH 19q determines the complete loss of EMP3 function, as the conserved allele is frequently hypermethylated, and this may represent the molecular basis of the higher risk of relapse in this subgroup of grade II oligodendroglioma patients.
The promoter methylation and mRNA expressions of EMP3 and PCDH-gamma-A11 (show PCDHgA11 Antibodies) are closely related with the malignant development of glioma.
EMP3 overexpression is associated with oligodendroglial tumors
Oligodendroglial and astrocytic gliomas show EMP3 hypermethylation and aberrant expression. Primary and secondary glioblastomas have distinct genetic profiles and also differ in their epigenetic aberrations.
Loss of EMP3 is associated with esophageal squamous cell carcinoma.
Probably involved in cell proliferation and cell-cell interactions.
epithelial membrane protein 3
, Epithelial membrane protein 3
, hematopoietic neural membrane protein 1