You are viewing an incomplete version of our website. Please click to reload the website as full version.

Epoxide Hydrolase 2, Cytoplasmic Proteins (EPHX2)

EPHX2 encodes a member of the epoxide hydrolase family. Additionally we are shipping Epoxide Hydrolase 2, Cytoplasmic Antibodies (67) and Epoxide Hydrolase 2, Cytoplasmic Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EPHX2 2053 P34913
EPHX2 13850 P34914
EPHX2 65030 P80299
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Epoxide Hydrolase 2, Cytoplasmic Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,586.00
Details
HOST_Baculovirus infected Insect Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

EPHX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Epoxide Hydrolase 2, Cytoplasmic (EPHX2) Interaction Partners

Human Epoxide Hydrolase 2, Cytoplasmic (EPHX2) interaction partners

  1. Increased levels of soluble epoxide hydrolase in the brain of depressed patients

  2. Interaction among CYP2C8, EPHX2, and CYP4A11 Gene Variants Significantly Increases the Risk for Ischemic Stroke.

  3. carriers of rs1042032 GG genotype had lower estimated glomerular filtration rate and higher serum creatinine values 1 year after grafting compared to patients carrying wildtype A-allele; this GG genotype also associated to increased risk of acute rejection; results suggest genetic variability in EPHX2 may have an impact on outcome of deceased-donor renal transplantation

  4. Suggest role for Ephx2 in vascular smooth muscle phenotypic modulation and migration in the development of atherosclerosis.

  5. Essential hypertension is associated with the rs751141 G/A allele gene polymorphism in EPHX2 in Han subjects but not in Kazakh and Uygur subjects.

  6. Within the EPHX2 promoter -56/+32, five Sp1 (show PSG1 Proteins)-binding sites were identified, and the mutation of each of these sites showed that the first one (SP1_1) was important in both suppression by Sp1 (show PSG1 Proteins) and activation by AP2alpha (show AP2A1 Proteins).

  7. A genetic variant that results in decreased soluble epoxide hydrolase activity is associated with increased insulin (show INS Proteins) sensitivity.

  8. Results show that CYP2C8 (show CYP2C8 Proteins) rs17110453 and EPHX2 rs751141 two-locus interaction confers a significantly higher risk for ischemic stroke.

  9. Patients with CYP2C8 (show CYP2C8 Proteins)*2C and EPHX2 404del variants had worse long-term outcomes while those with EPHX2 287Gln, CYP2J2 (show CYP2J2 Proteins)*7, and CYP2C9 (show CYP2C9 Proteins) g.816G variants had favorable outcomes.

  10. Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo.

Mouse (Murine) Epoxide Hydrolase 2, Cytoplasmic (EPHX2) interaction partners

  1. we identified 31 significantly expressed proteins in mouse hippocampus using proteomics analysis and constructed a protein-protein interaction network associated with EPHX2 gene knockout

  2. The role of soluble epoxide hydrolase in the pathophysiology of depression and resilience to repeated social defeat stress

  3. CYP-eicosanoid profiling also revealed that renal, but not plasma and hepatic, 20-HETE levels were significantly increased in sEH-KO compared to WT mice

  4. Dual inhibition of c-Raf (show RAF1 Proteins) and soluble epoxide hydrolase by t-CUPM prevents mutant KrasG12D-initiated murine pancreatic carcinoma growth.

  5. sEH deficiency attenuated tyrosine hydroxylase (show TH Proteins)-positive cell loss in a paraquat-induced mouse model of Parkinson's.

  6. Simultaneous inhibition of sEH and c-RAF (show RAF1 Proteins) prevents chronic pancreatitis and murine pancreatic intraepithelial neoplasia in LSL-KrasG(1)(2)D/Pdx-1 (show PDX1 Proteins)-Cre mice.

  7. Suggest role for Ephx2 in vascular smooth muscle phenotypic modulation and migration in the development of atherosclerosis.

  8. Sex-different regulation of sEH accounts for sex differences in flow-mediated dilation of microvessels in gonadally intact mice.

  9. HS-induced contraction in A2AAR (show ADORA2A Proteins)(-/-) mice was attenuated by sEH inhibitor.. the contribution of EETs, PPARgamma (show PPARG Proteins) and KATP channels downstream of A2AAR (show ADORA2A Proteins) to mediate enhanced vascular relaxation in response to HS diet

  10. Suggest that sEH inhibition may be a promising strategy to treat atherosclerotic vascular disease.

Cow (Bovine) Epoxide Hydrolase 2, Cytoplasmic (EPHX2) interaction partners

  1. AP-1 (show JUN Proteins) activation is involved in the transcriptional up-regulation of sEH by angiotensin II (Ang II) in endothelial cells, which may contribute to Ang II (show AGT Proteins)-induced hypertension[soluble epoxide hydrolase ]

Epoxide Hydrolase 2, Cytoplasmic (EPHX2) Protein Profile

Protein Summary

This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with EPHX2

  • epoxide hydrolase 2, cytoplasmic (EPHX2)
  • soluble epoxide hydrolase (SEH2)
  • soluble epoxide hydrolase (PTRG_01276)
  • Soluble epoxide hydrolase (Deima_0402)
  • Soluble epoxide hydrolase (Deipr_0144)
  • Soluble epoxide hydrolase (Psed_0418)
  • Soluble epoxide hydrolase (Fluta_3767)
  • Soluble epoxide hydrolase (Halxa_3281)
  • epoxide hydrolase 2, cytoplasmic (Ephx2)
  • CEH protein
  • Eph2 protein
  • SEH protein
  • sEP protein

Protein level used designations for EPHX2

epoxide hydrolase 2 , soluble epoxide hydrolase , Soluble epoxide hydrolase , bifunctional epoxide hydrolase 2 , epoxide hydratase , epoxide hydrolase 2, cytosolic , epoxide hydrolase, soluble , cytosolic epoxide hydrolase , epoxide hydrolase 2C , CEH , SEH

GENE ID SPECIES
421999 Gallus gallus
4836743 Scheffersomyces stipitis CBS 6054
6339307 Pyrenophora tritici-repentis Pt-1C-BFP
10149715 Deinococcus maricopensis DSM 21211
10255604 Deinococcus proteolyticus MRP
10362229 Pseudonocardia dioxanivorans CB1190
10399141 Fluviicola taffensis DSM 16823
10798230 Halopiger xanaduensis SH-6
2053 Homo sapiens
13850 Mus musculus
65030 Rattus norvegicus
477373 Canis lupus familiaris
414425 Sus scrofa
511716 Bos taurus
Selected quality suppliers for Epoxide Hydrolase 2, Cytoplasmic Proteins (EPHX2)
Did you look for something else?