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Epsin 2 Proteins (EPN2)

Plays a role in the formation of clathrin-coated invaginations and endocytosis.. Additionally we are shipping Epsin 2 Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EPN2 22905 O95208
EPN2 13855 Q8CHU3
Rat EPN2 EPN2 60443 Q9Z1Z3
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Top Epsin 2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EPN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Epsin 2 (EPN2) Interaction Partners

Fruit Fly (Drosophila melanogaster) Epsin 2 (EPN2) interaction partners

  1. At least one of the functions of Drosophila Tel2/EpsinR is regulation of Wingless signaling.

Human Epsin 2 (EPN2) interaction partners

  1. Epsins are required for Dishevelled (show DVL2 Proteins) stability and Wnt (show WNT2 Proteins) signalling activation in colon cancer development.

Mouse (Murine) Epsin 2 (EPN2) interaction partners

  1. Epsins are required for Dishevelled (show DVL2 Proteins) stability and Wnt (show WNT2 Proteins) signalling activation in colon cancer development.

  2. epsins 1 and 2 have a critical role in the temporal and spatial regulation of VEGFR3 (show FLT4 Proteins) abundance and signaling in collecting lymphatic trunks during lymphatic valve formation

  3. Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.

  4. Epsins function specifically to downregulate VEGFR2 by mediating activated VEGFR2 internalization and degradation and that genetic reduction of VEGFR2 level protects against excessive angiogenesis caused by epsin loss.

  5. Loss of epsins 1 and 2 impaired endocytosis and degradation of VEGFR2, resulting in excessive VEGF signaling and compromised tumor vascular function.

  6. epsin has a role as a specialized endocytic adaptor, with a critical role in the activation of Notch (show NOTCH1 Proteins) signaling in mammals

Epsin 2 (EPN2) Protein Profile

Protein Summary

Plays a role in the formation of clathrin-coated invaginations and endocytosis.

Gene names and symbols associated with Epsin 2 Proteins (EPN2)

  • liquid facets-Related (lqfR)
  • epsin 2 (EPN2)
  • epsin-2 (EDI_326810)
  • epsin-2 (EDI_044850)
  • Epsin 2 (Bm1_38210)
  • epsin-2 (EHI_104950)
  • epsin 2 (epn2)
  • epsin 2 (Epn2)
  • 9530051D10Rik protein
  • AA536924 protein
  • CG13853 protein
  • CG13854 protein
  • CG31170 protein
  • CG31285 protein
  • CG42250 protein
  • Dmel\\CG42250 protein
  • Dmel_CG31170 protein
  • Dmel_CG31285 protein
  • EHB21 protein
  • epsin protein
  • epsin-2 protein
  • epsin-like protein
  • epsin02 protein
  • epsinR protein
  • Ibp2 protein
  • l(3)03685 protein
  • l(3)A9 protein
  • l(3)dsl-9 protein
  • l(3)dsl9 protein
  • l(3)SG62 protein
  • l(3)XII-10 protein
  • LqfR protein
  • XII-10 protein

Protein level used designations for Epsin 2 Proteins (EPN2)

CG42250-PC , CG42250-PD , EpsinR , epsin-2 , epsin-like , lethal (3) SG62 , liquid facet related , liquid facets related , liquid-facets related , lqfR-PC , lqfR-PD , epsin 2 , Epsin 2 , EPS-15-interacting protein 2 , Eps15 binding protein , intersectin-EH-binding protein 2 , EH domain binding protein epsin 2 , mitotic phosphoprotein 90

GENE ID SPECIES
42632 Drosophila melanogaster
454498 Pan troglodytes
5878933 Entamoeba dispar SAW760
5882892 Entamoeba dispar SAW760
6102526 Brugia malayi
6219633 Entamoeba histolytica HM-1:IMSS
100172068 Pongo abelii
100216083 Xenopus (Silurana) tropicalis
22905 Homo sapiens
13855 Mus musculus
60443 Rattus norvegicus
398106 Xenopus laevis
416524 Gallus gallus
505336 Bos taurus
489533 Canis lupus familiaris
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