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EBI3 was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. Additionally we are shipping EBI3 Antibodies (114) and EBI3 Kits (10) and many more products for this protein.
Showing 10 out of 27 products:
Human EBI3 Protein expressed in Wheat germ - ABIN3013374
Guttek, Reinhold: Stimulated human peripheral T cells produce high amounts of IL-35 protein in a proliferation-dependent manner. in Cytokine 2013
IL-35 was elevated in bone marrow of adult AML (show RUNX1 Proteins) patients and this increase was correlated with the clinical stages of malignancy, suggesting that IL-35 is involved in pathogenesis of AML (show RUNX1 Proteins).
Data suggest that the toll like receptor 3 (TLR3 (show TLR3 Proteins))-interferon regulatory factor 6 (show IRF6 Proteins) protein (IRF6 (show IRF6 Proteins))-interleukin-23 subunit p19 (p19 (show IL23A Proteins))/EBI3 protein axis may regulate keratinocyte functions in the skin.
EBI3 gene rs4740 polymorphism is closely associated wit (show SLC11A1 Proteins)h susceptibility to pulmonary tuberculosis and the elevation and enrichment of EBI3 in the lung derived from macrophages may contribute to the exacerbation of mycobacterial infection.
EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.
IL-35 can effectively suppress the proliferation and IL-4 (show IL4 Proteins) production of activated CD4 (show CD4 Proteins)+CD25 (show IL2RA Proteins)- T cells in allergic asthma, and that IL-35 may be a new immunotherapy for asthma patients.
IL-35 is highly expressed in chronic HBV CD4 (show CD4 Proteins)(+) T-cells and plays an important role in the inhibition of the cellular immune response in chronic HBV.
The levels of EBI3 and IL-12p35 mRNAs in peripheral blood mononuclear cells in moderate or hyper-responders were significantly higher than those in non- or hypo-responders.
IL-17 (show IL17A Proteins) and IL-35 may be critically involved in the pathogenesis of hepatitis B-related LC.
IL35 appears to contribute to the loss of immunological self-tolerance in ITP (show ITPA Proteins) patients by modulating T cells and immunoregulatory cytokines.
Interleukin-35 induces regulatory B cells that suppress autoimmune disease. [il-35]
our results demonstrate that EBI3 is an essential general regulator of inflammatory immune responses in experimental Chagas disease
Report higher EBI3 expression in the lung tissue of BCG (show SLC11A1 Proteins)-infected mice.
IL-35 subunits (p35 and EBI3) have the immunoregulatory role in systemic lupus erythematosus.
Lack of EBI3, p35 (show CDK5R1 Proteins), and IL-12 (show IL12A Proteins) receptor beta2 caused enhanced infiltration of lymphocytes into the testicular interstitium, with increased interferon-gamma (show IFNG Proteins) expression in the testes and autoantibody production against mainly acrosomal regions of spermatids.
Data (including data from knockout mice) suggest Ebi3 (Epstein-Barr virus induced protein 3 (show HSPB3 Proteins)) and IL12 (show IL12A Proteins) (interleukin 12) down-regulate helper-inducer T-lymphocyte (Th17 cell) function in immune response to Listeria monocytogenes.
results indicate that EBI3 may be important in EAU initiation by Th1 (show HAND1 Proteins) cell responses and may suppress experimental autoimmune uveitis by inhibition of both Th1 (show HAND1 Proteins) and Th17 cell responses in the late/maintenance phase.
Anti-CD200R2 (show CD200R1L Proteins), anti-IL-9 (show IL9 Proteins), anti-IL-35, or anti-TGF-beta (show TGFB1 Proteins) abolishes increased graft survival and Treg induction induced in cromolyn-treated CD200R1KO.CD200tg mice, and suggest combined role of mast cells and Tregs.
the findings from the past decade identify IL-27 (show IL27 Proteins) as a critical immunoregulatory cytokine, especially for T cells, whereas some controversy is fueled by results challenging the view of IL-27 (show IL27 Proteins) as a classical silencer of inflammation.
These data demonstrate a regulatory role for EBI3-associated cytokines in controlling host responses following CNS viral infection.
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
EBV-induced gene 3 protein
, Epstein-Barr virus induced gene 3
, IL-27 subunit beta
, IL27 subunit
, IL35 subunit
, cytokine receptor
, epstein-Barr virus-induced gene 3 protein
, interleukin-27 subunit beta
, Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor)
, epstein-Barr virus-induced gene 3 protein homolog