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EBI3 was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. Additionally we are shipping EBI3 Antibodies (123) and EBI3 Proteins (28) and many more products for this protein.
Showing 4 out of 14 products:
Mouse (Murine) EBI3 ELISA Kit for Sandwich ELISA - ABIN426379
Dibra, Cutrera, Li: Coordination between TLR9 signaling in macrophages and CD3 signaling in T cells induces robust expression of IL-30. in Journal of immunology (Baltimore, Md. : 1950) 2012
over-expression of EBI3 could reduce the apoptosis of Treg/CD4 (show CD4 ELISA Kits)(+)T/CD8 (show CD8A ELISA Kits)(+)T cells and prevent radiation-induced immunosuppression of cervical cancer HeLa cells by inhibiting the activation of PD-1 (show PDCD1 ELISA Kits)/PD-L1 (show CD274 ELISA Kits) signaling pathway
Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) levels were significantly elevated in the patients with influenza infection.
IL-35 was elevated in bone marrow of adult AML (show RUNX1 ELISA Kits) patients and this increase was correlated with the clinical stages of malignancy, suggesting that IL-35 is involved in pathogenesis of AML (show RUNX1 ELISA Kits).
Data suggest that the toll like receptor 3 (TLR3 (show TLR3 ELISA Kits))-interferon regulatory factor 6 (show IRF6 ELISA Kits) protein (IRF6 (show IRF6 ELISA Kits))-interleukin-23 subunit p19 (p19 (show IL23A ELISA Kits))/EBI3 protein axis may regulate keratinocyte functions in the skin.
EBI3 gene rs4740 polymorphism is closely associated wit (show SLC11A1 ELISA Kits)h susceptibility to pulmonary tuberculosis and the elevation and enrichment of EBI3 in the lung derived from macrophages may contribute to the exacerbation of mycobacterial infection.
EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.
IL-35 can effectively suppress the proliferation and IL-4 (show IL4 ELISA Kits) production of activated CD4 (show CD4 ELISA Kits)+CD25 (show IL2RA ELISA Kits)- T cells in allergic asthma, and that IL-35 may be a new immunotherapy for asthma patients.
IL-35 is highly expressed in chronic HBV CD4 (show CD4 ELISA Kits)(+) T-cells and plays an important role in the inhibition of the cellular immune response in chronic HBV.
The levels of EBI3 and IL-12p35 mRNAs in peripheral blood mononuclear cells in moderate or hyper-responders were significantly higher than those in non- or hypo-responders.
IL-17 (show IL17A ELISA Kits) and IL-35 may be critically involved in the pathogenesis of hepatitis B-related LC.
Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) expressing plasmid downregulates the expression of pro-inflammatory cytokines and upregulates the expression of anti-inflammatory cytokines.
IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors
Data suggest that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) contributes to the increased susceptibility to secondary pneumococcal pneumonia.
our results demonstrate that EBI3 is an essential general regulator of inflammatory immune responses in experimental Chagas disease
Report higher EBI3 expression in the lung tissue of BCG (show SLC11A1 ELISA Kits)-infected mice.
IL-35 subunits (p35 and EBI3) have the immunoregulatory role in systemic lupus erythematosus.
Lack of EBI3, p35 (show CDK5R1 ELISA Kits), and IL-12 (show IL12A ELISA Kits) receptor beta2 caused enhanced infiltration of lymphocytes into the testicular interstitium, with increased interferon-gamma (show IFNG ELISA Kits) expression in the testes and autoantibody production against mainly acrosomal regions of spermatids.
Data (including data from knockout mice) suggest Ebi3 (Epstein-Barr virus induced protein 3 (show HSPB3 ELISA Kits)) and IL12 (show IL12A ELISA Kits) (interleukin 12) down-regulate helper-inducer T-lymphocyte (Th17 cell) function in immune response to Listeria monocytogenes.
results indicate that EBI3 may be important in EAU initiation by Th1 (show HAND1 ELISA Kits) cell responses and may suppress experimental autoimmune uveitis by inhibition of both Th1 (show HAND1 ELISA Kits) and Th17 cell responses in the late/maintenance phase.
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
EBV-induced gene 3 protein
, Epstein-Barr virus induced gene 3
, IL-27 subunit beta
, IL27 subunit
, IL35 subunit
, cytokine receptor
, epstein-Barr virus-induced gene 3 protein
, interleukin-27 subunit beta
, Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor)
, epstein-Barr virus-induced gene 3 protein homolog