Epstein-Barr Virus Induced 3 Proteins (EBI3)

EBI3 was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. Additionally we are shipping EBI3 Antibodies (124) and EBI3 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EBI3 10148 Q14213
Rat EBI3 EBI3 680609  
EBI3 50498 O35228
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Top EBI3 Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_CHO Cells Human His tag   10 μg Log in to see 12 to 15 Days
$345.35
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 4 to 6 Days
$638.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 4 to 6 Days
$638.00
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 15 to 18 Days
$736.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.02 mg Log in to see 2 to 6 Days
$270.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   0.01 mg Log in to see 2 to 6 Days
$270.00
Details

EBI3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine) ,
,

Top referenced EBI3 Proteins

  1. Human EBI3 Protein expressed in CHO Cells - ABIN2719909 : Wang, Wei, Xiao, Liu, Zhang, Han, Chen, Hou, Ma, Shen, Li, Egwuagu, Wang: A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice. in European journal of immunology 2016 (PubMed)

  2. Human EBI3 Protein expressed in Wheat germ - ABIN3013374 : Guttek, Reinhold: Stimulated human peripheral T cells produce high amounts of IL-35 protein in a proliferation-dependent manner. in Cytokine 2013 (PubMed)

More Proteins for Epstein-Barr Virus Induced 3 (EBI3) Interaction Partners

Human Epstein-Barr Virus Induced 3 (EBI3) interaction partners

  1. The plasma levels of interleukin-35 were significantly higher in the hepatocellular carcinoma patients than the controls.

  2. over-expression of EBI3 could reduce the apoptosis of Treg/CD4 (show CD4 Proteins)(+)T/CD8 (show CD8A Proteins)(+)T cells and prevent radiation-induced immunosuppression of cervical cancer HeLa cells by inhibiting the activation of PD-1 (show PDCD1 Proteins)/PD-L1 (show CD274 Proteins) signaling pathway

  3. Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) levels were significantly elevated in the patients with influenza infection.

  4. IL-35 was elevated in bone marrow of adult AML (show RUNX1 Proteins) patients and this increase was correlated with the clinical stages of malignancy, suggesting that IL-35 is involved in pathogenesis of AML (show RUNX1 Proteins).

  5. Data suggest that the toll like receptor 3 (TLR3 (show TLR3 Proteins))-interferon regulatory factor 6 (show IRF6 Proteins) protein (IRF6 (show IRF6 Proteins))-interleukin-23 subunit p19 (p19 (show IL23A Proteins))/EBI3 protein axis may regulate keratinocyte functions in the skin.

  6. EBI3 gene rs4740 polymorphism is closely associated wit (show SLC11A1 Proteins)h susceptibility to pulmonary tuberculosis and the elevation and enrichment of EBI3 in the lung derived from macrophages may contribute to the exacerbation of mycobacterial infection.

  7. EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.

  8. IL-35 can effectively suppress the proliferation and IL-4 (show IL4 Proteins) production of activated CD4 (show CD4 Proteins)+CD25 (show IL2RA Proteins)- T cells in allergic asthma, and that IL-35 may be a new immunotherapy for asthma patients.

  9. IL-35 is highly expressed in chronic HBV CD4 (show CD4 Proteins)(+) T-cells and plays an important role in the inhibition of the cellular immune response in chronic HBV.

  10. The levels of EBI3 and IL-12p35 mRNAs in peripheral blood mononuclear cells in moderate or hyper-responders were significantly higher than those in non- or hypo-responders.

Mouse (Murine) Epstein-Barr Virus Induced 3 (EBI3) interaction partners

  1. we describe here a new IL-12 member IL-39 (IL-23p19/Ebi3) secreted by activated B cells that mediate inflammatory responses in lupus-like mice. Thus, IL-39 might contribute to immunopathogenic mechanisms of SLE.

  2. EBI3 can mediate IL-6 (show IL6 Proteins) trans-signaling in a process that involves gp130 (show LRPPRC Proteins)

  3. Data show that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) expressing plasmid downregulates the expression of pro-inflammatory cytokines and upregulates the expression of anti-inflammatory cytokines.

  4. IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors

  5. Data suggest that interleukin-35 (Epstein-Barr virus-induced gene 3 (EBI3) and the interleukin-12 Subunit p35 (p35) subunit) contributes to the increased susceptibility to secondary pneumococcal pneumonia.

  6. our results demonstrate that EBI3 is an essential general regulator of inflammatory immune responses in experimental Chagas disease

  7. Report higher EBI3 expression in the lung tissue of BCG (show SLC11A1 Proteins)-infected mice.

  8. EBI3 Downregulation Contributes to Type I Collagen Overexpression in Scleroderma Skin.

  9. IL-35 subunits (p35 and EBI3) have the immunoregulatory role in systemic lupus erythematosus.

  10. Lack of EBI3, p35 (show CDK5R1 Proteins), and IL-12 (show IL12A Proteins) receptor beta2 caused enhanced infiltration of lymphocytes into the testicular interstitium, with increased interferon-gamma (show IFNG Proteins) expression in the testes and autoantibody production against mainly acrosomal regions of spermatids.

EBI3 Protein Profile

Protein Summary

This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.

Gene names and symbols associated with EBI3

  • Epstein-Barr virus induced 3 (EBI3)
  • Epstein-Barr virus induced 3 (Ebi3)
  • Epstein-Barr virus induced gene 3 (Ebi3)
  • EBI-3 protein
  • IL-27 protein
  • IL-27B protein
  • IL27B protein

Protein level used designations for EBI3

EBV-induced gene 3 protein , Epstein-Barr virus induced gene 3 , IL-27 subunit beta , IL27 subunit , IL35 subunit , cytokine receptor , epstein-Barr virus-induced gene 3 protein , interleukin-27 subunit beta , Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor) , IL-27B , epstein-Barr virus-induced gene 3 protein homolog

GENE ID SPECIES
10148 Homo sapiens
680609 Rattus norvegicus
50498 Mus musculus
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