Essential Meiotic Endonuclease 1 Homolog 2 (S. Pombe) (EME2) ELISA Kits

EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008].. Additionally we are shipping EME2 Antibodies (25) and EME2 Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat EME2 EME2 302982  
Anti-Mouse EME2 EME2 193838 Q56A04
Anti-Human EME2 EME2 197342 A4GXA9
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More ELISA Kits for EME2 Interaction Partners

Human Essential Meiotic Endonuclease 1 Homolog 2 (S. Pombe) (EME2) interaction partners

  1. Avoiding damage formation through invalidation of Mus81 (show MUS81 ELISA Kits)-Eme2 and Mre11 (show MRE11A ELISA Kits), or preventing damage signaling by turning off the ATM (show ATM ELISA Kits) pathway, suppresses the replication phenotypes of Chk1 (show CHEK1 ELISA Kits)-deficient cells.

  2. Results define distinct and temporal roles for MUS81 (show MUS81 ELISA Kits)-EME1 (show EME1 ELISA Kits) and MUS81 (show MUS81 ELISA Kits)-EME2 in the maintenance of genome stability.

  3. The presence of a 5' phosphate terminus at nicks and gaps rendered DNA significantly less susceptible to the cleavage by MUS81 (show MUS81 ELISA Kits)-EME2 than its absence.

  4. The results indicate that MUS81 (show MUS81 ELISA Kits)-EME2 is a more active endonuclease than MUS81 (show MUS81 ELISA Kits)-EME1 (show EME1 ELISA Kits) and exhibits broader substrate specificity.

EME2 Antigen Profile

Antigen Summary

EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007

Gene names and symbols associated with EME2

  • essential meiotic structure-specific endonuclease subunit 2 (Eme2) antibody
  • essential meiotic endonuclease 1 homolog 2 (S. pombe) (EME2) antibody
  • essential meiotic structure-specific endonuclease subunit 2 (EME2) antibody
  • essential meiotic endonuclease 1 homolog 2 (S. pombe) (Eme2) antibody
  • 2810013J18Rik antibody
  • gs125 antibody
  • RGD1304924 antibody
  • SLX2B antibody

Protein level used designations for EME2

essential meiotic endonuclease 1 homolog 2 , probable crossover junction endonuclease EME2 , essential meiotic endonuclease 1 homolog 2 (S. pombe) , SLX2 structure-specific endonuclease subunit homolog B , homolog of yeast EME1 endonuclease 2

GENE ID SPECIES
302982 Rattus norvegicus
416400 Gallus gallus
467868 Pan troglodytes
515662 Bos taurus
722482 Macaca mulatta
193838 Mus musculus
197342 Homo sapiens
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