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ETV1 encodes a member of the ETS (E twenty-six) family of transcription factors. Additionally we are shipping ETV1 Antibodies (70) and ETV1 Proteins (5) and many more products for this protein.
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the prostate cancer-related oncogenic E26 transformation-specific (ETS (show ETS1 ELISA Kits)) transcription factors, ETV1, ETV4 (show ETV4 ELISA Kits), and ETV5, were required for TAZ (show TAZ ELISA Kits) gene transcription in PC3 (show PCSK1 ELISA Kits) prostate cancer cells
C646 treatment attenuated ETV1 protein expression and inactivated KIT-dependent pathways. Taken together, the present study suggests that CBP/p300 (show CREBBP ELISA Kits) may serve as novel antineoplastic targets and that use of the selective HAT (show MGEA5 ELISA Kits) inhibitor C646 is a promising antitumor strategy for Gastrointestinal stromal tumors.
these data reveal a JMJD2A (show KDM4A ELISA Kits)/ETV1/YAP1 (show YAP1 ELISA Kits) axis that promotes prostate cancer initiation and that may be a suitable target for therapeutic inhibition.
conclude that ETV1 is specifically expressed in the majority of gastrointestinal stromal tumors, even in some KIT-negative cases
ETV1 and COP1 (show CARD16 ELISA Kits) are a pair of independent predictors of prognosis for triple-negative breast cancer.
ETV1 overexpression is associated with prostate cancer aggressiveness.
Results show that ETV1 was upregulated at a higher rate in Gastrointestinal stromal tumor and was correlated with KIT expression.
These results illuminate the complex interplay of AR, ETV1, and PTEN pathways in pre-cancerous neoplasia and early tumorigenesis
YK-4-279 is a potent inhibitor of ETV1 and inhibits both the primary tumor growth and metastasis of fusion positive prostate cancer xenografts.
mutation of the KIT protein that stabilizes ETV1 is likely to be a key step by which an endogenous brain-cell progenitor may form a germinoma.
we conclude that Etv1 acts downstream of FGF signaling to regulate the initiation of neurogenesis in the Xenopus retina.
Thus, taken into consideration the mechanism that controls the upregulation of maturation genes involved in synaptic formation, these results indicate that Etv1 orchestrates the activity-dependent regulation of both maturation and immaturation genes in developing granule cells and plays a key role in specifying the identity of mature granule cells in the cerebellum.
downstream ETV1/4/5 transcriptional up-regulation appears highly sensitive and specific and can be used as a reliable molecular signature and diagnostic method for CIC (show CIC ELISA Kits) fusion positive SBRCTs
this study shows that network activity dynamically modulates the properties of fast-spiking (FS) interneurons through the postmitotic expression of the transcriptional regulator Er81.
Data showed that ETV1 knockdown reduced KIT expression and GIST proliferation.
both Etv1 and Ewsr1 (show EWSR1 ELISA Kits) were necessary for Fgf10 (show FGF10 ELISA Kits) expression and elongation of the limb bud.
ETV1 appeared to support development of invasive adenocarcinoma under the background of full Pten loss
Study shows that the NR2C (show GRIN2C ELISA Kits) and Tiam1 maturation genes are synergistically controlled by the activity-dependent induction of Etv1.
The coordinate expression of Etv1 with POMC (show POMC ELISA Kits) cell differentiation and its interaction with the highly cell-restricted Tpit (show TBX19 ELISA Kits) factor indicate that Etv1 participates in a combinatorial code for pituitary cell-specific gene expression.
Etv1 orchestrates the activity-dependent gene regulation in the terminal maturation program and specifies the identity of cerebellar granule cells.
er81 embryonic expression regulation does not require FGF signalling.
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA
ets variant 1
, ets domain protein
, ets variant gene 1
, ETS translocation variant 1
, ets-related protein 81
, ets-related transcription factor XER81
, ets related protein 81
, ETS transcription factor Er81