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anti-Ets Variant 4 (ETV4) Antibodies

Transcriptional activator that binds to the enhancer of the adenovirus E1A gene\; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.. Additionally we are shipping ETV4 Proteins (5) and ETV4 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ETV4 2118 P43268
ETV4 360635  
ETV4 18612  
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Top anti-ETV4 Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ETV4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using ETV4 mouse mAb against K562 cell lysate (1) . Figure 2: Western blot analysis using ETV4 mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ETV4 cDNA (2) . 100 μL Log in to see 3 to 4 Days
$442.20
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ETV4 antibody (C-term) (ABIN390582) in mouse heart tissue lysates (35 µg/lane). ETV4 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ETV4 (arrow) using rabbit polyclonal ETV4 Antibody (C-term) (ABIN390582). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ETV4 gene (Lane 2) . 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with ETV4 antibody ABIN214103 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Breast (formalin-fixed, paraffin-embedded) stained with ETV4 antibody ABIN214103 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of ETV4 expression in transfected 293T cell line by ETV4 monoclonal antibody (M01), clone 3G9-1B9.Lane 1: ETV4 transfected lysate(54 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged ETV4 is 0.1 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$434.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μL Log in to see 6 to 8 Days
$500.50
Details

ETV4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ETV4 Antibodies

  1. Cow (Bovine) Polyclonal ETV4 Primary Antibody for WB - ABIN2779533 : Span, Manders, Heuvel, Beex, Sweep: E1AF expression levels are not associated with prognosis in human breast cancer. in Breast cancer research and treatment 2003 (PubMed)
    Show all 4 references for ABIN2779533

  2. Human Monoclonal ETV4 Primary Antibody for WB - ABIN1107153 : Yu, Xia, Wang, Wang, Pan, Kwong, Hortobagyi, Hung: Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1. in Molecular carcinogenesis 2006 (PubMed)
    Show all 3 references for ABIN1107153

  3. Human Monoclonal ETV4 Primary Antibody for ELISA, WB - ABIN969121 : Zhu, Jiang, Shen, Wang, Zong, Li, Yang, Niu, Liu, Chen, Hu, Gu: Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator. in The Journal of biological chemistry 2005 (PubMed)
    Show all 3 references for ABIN969121

  4. Human Monoclonal ETV4 Primary Antibody for ELISA, WB - ABIN560805 : Han, Mehra, Dhanasekaran, Yu, Menon, Lonigro, Wang, Gong, Wang, Shankar, Laxman, Shah, Varambally, Palanisamy, Tomlins, Kumar-Sinha, Chinnaiyan: A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer. in Cancer research 2008 (PubMed)
    Show all 2 references for ABIN560805

  5. Human Polyclonal ETV4 Primary Antibody for IHC, ELISA - ABIN1533733 : Friedman, Ostermeyer, Lynch, Welcsh, Szabo, Meza, Anderson, Dowd, Lee, Rowell: 22 genes from chromosome 17q21: cloning, sequencing, and characterization of mutations in breast cancer families and tumors. in Genomics 1995 (PubMed)
    Show all 2 references for ABIN1533733

  6. Human Polyclonal ETV4 Primary Antibody for EIA, FACS - ABIN452983 : Wei, Liu, Ge, Zhou, Xu, Chen, Gu, Jiang: Identification of E1AF as a target gene of E2F1-induced apoptosis in response to DNA damage. in Journal of biochemistry 2008 (PubMed)

More Antibodies against ETV4 Interaction Partners

Human Ets Variant 4 (ETV4) interaction partners

  1. PEA3-subgroup transcription factors are key players of the Met signaling integration involved in regulation of migration and invasiveness of tumor cells.

  2. ACC1 (show ACACA Antibodies) and ACLY (show ACLY Antibodies) regulate the levels of ETV4 under hypoxia via increased alpha-ketoglutarate. These results reveal that the ACC1 (show ACACA Antibodies)/ACLY (show ACLY Antibodies)-alpha-ketoglutarate-ETV4 axis is a novel means by which metabolic states regulate transcriptional output

  3. ETV4 overexpression is associated with prostate cancer aggressiveness.

  4. molecular mechanism underlying DBC1 (show DBC1 Antibodies) function in PEA3-mediated transcription involves inhibition of SIRT1 (show SIRT1 Antibodies) interaction with PEA3 and of SIRT1 (show SIRT1 Antibodies)-mediated deacetylation of PEA3

  5. Implicate Pea3 as a mediator of liver metastases in colorectal cancer.

  6. Silencing of ETV4 suppresses invasion of prostate cancer cells by inhibiting the expression of uPA (show PRAP1 Antibodies)/uPAR (show PLAUR Antibodies) as well as (MMP)-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies)

  7. data suggest that polyomavirus enhancer activator 3 and epithelium-specific transcription factor-1 (show HNF1A Antibodies) may play important roles in pluri potent and tumorigenic embryonic carcinoma cells.

  8. developed a novel RNA in situ hybridization-based assay for the in situ detection of ETV1 (show ETV1 Antibodies), ETV4, and ETV5 (show ETV5 Antibodies) in formalin-fixed paraffin-embedded tissues from prostate needle biopsies, prostatectomy, and metastatic PCa (show FLVCR1 Antibodies) specimens using RNA probes

  9. PEA3 regulates OCT4 (show POU5F1 Antibodies) gene expression as a transcriptional activator

  10. Study reveals molecular insight into how the Ets (show ETS1 Antibodies) family transcription factor Pea3 favors EMT (show ITK Antibodies) and contributes to tumorigenesis via a negative regulatory loop with Cyclin D2 (show CCND2 Antibodies), a new Pea3 target gene.

Zebrafish Ets Variant 4 (ETV4) interaction partners

  1. etv5a (show ETV5 Antibodies) and etv4 have roles in mediating epithelial cell fate during zebrafish kidney development

  2. Pea3 and erm (show ETV5 Antibodies) are required for zebrafish pronephrogenesis and can functionally complement each other, and the wt1a gene may be one of their downstream targets.

  3. Overlapping functions of pea3 ETS (show ETS1 Antibodies) transcription factors in FGF signaling during zebrafish development are reported.

Mouse (Murine) Ets Variant 4 (ETV4) interaction partners

  1. ETS-related transcription factors ETV4 and ETV5 (show ETV5 Antibodies) are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells.

  2. paracrine signaling via fibroblast growth factor 2 (Fgf2 (show FGF2 Antibodies)) and Mapk (show MAPK1 Antibodies) between these diverged tumor subclones causes enhanced expression of the Pea3 transcription factor, resulting in metastatic dissemination of the neuroendocrine tumor subclones.

  3. Study hypothesized that PEA3 might play an essential role in the activation of the FAK (show PTK2 Antibodies) gene during tumor metastasis.

  4. Study reveals molecular insight into how the Ets (show ETS1 Antibodies) family transcription factor Pea3 favors EMT (show ITK Antibodies) and contributes to tumorigenesis via a negative regulatory loop with Cyclin D2 (show CCND2 Antibodies), a new Pea3 target gene.

  5. oncogenic Etv4 promotes prostate cancer metastasis in response to coactivation of PI3-kinase and Ras signaling pathways in a genetically engineered model of highly penetrant, metastatic prostate cancer

  6. PEA3-null fibroblasts exhibit impaired c-src activation and motility defects.

  7. Smad2 (show SMAD2 Antibodies) and PEA3 regulate RGC-32 (show C13orf15 Antibodies) transcription which is essential for smooth muscle cell differentiation from neural crest cells.

  8. study provides evidence for a protumorigenic role of PEA3 factors in breast neoplasia, and supports targeting the PEA3 transcription factor family in breast cancer

  9. Induction of Pea3 gene expression by peripheral signals is required to coordinate the central position and terminal arborization of specific sets of spinal motor neurons.

  10. PEA3 expression in developing motor neurons is regulated by GDNF (show GDNF Antibodies) signals from the limb bud.

ETV4 Antigen Profile

Protein Summary

Transcriptional activator that binds to the enhancer of the adenovirus E1A gene\; the core-binding sequence is 5'GT-3'.

Gene names and symbols associated with anti-Ets Variant 4 (ETV4) Antibodies

  • ets variant 4 (ETV4) antibody
  • ets variant gene 4 (E1A enhancer binding protein, E1AF) (ETV4) antibody
  • ets variant 4 (Etv4) antibody
  • ets variant gene 4 (etv4) antibody
  • ets variant gene 4 (E1A enhancer binding protein, E1AF) (Etv4) antibody
  • AW414408 antibody
  • E1A-F antibody
  • E1AF antibody
  • ETV4 antibody
  • Pea-3 antibody
  • pea3 antibody
  • PEAS3 antibody

Protein level used designations for anti-Ets Variant 4 (ETV4) Antibodies

ets variant 4 , ETS translocation variant gene 4 , ets variant gene 4 (E1A enhancer binding protein, E1AF) , ets domain protein , ETS translocation variant 4 , EWS protein/E1A enhancer binding protein chimera , adenovirus E1A enhancer-binding protein , ets variant gene 4 (E1A enhancer-binding protein, E1AF) , polyomavirus enhancer activator 3 homolog , ETS translocation variant 4-like , polyomavirus enhancer activator-3 , ETS domain-containing transcription factor PEA3 , ETS-domain transcription factor pea3 , etID309954.12 , ETS variant protein 4 , POLYOMAVIRUS ENHANCER ACTIVATOR 3 (PEA3 PROTEIN) (ETS TRANSLOCATION VARIANT 4)

GENE ID SPECIES
281149 Bos taurus
395747 Gallus gallus
454715 Pan troglodytes
100065121 Equus caballus
2118 Homo sapiens
533129 Bos taurus
360635 Rattus norvegicus
403641 Canis lupus familiaris
30700 Danio rerio
18612 Mus musculus
Selected quality suppliers for anti-ETV4 (ETV4) Antibodies
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