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anti-Ets Variant 6 (ETV6) Antibodies

ETV6 encodes an ETS family transcription factor. Additionally we are shipping ETV6 Proteins (4) and ETV6 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ETV6 2120 P41212
ETV6 312777  
ETV6 14011 P97360
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Top anti-ETV6 Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ETV6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-ETV6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HeLa/HepG2/Jurkat cells, using ETV6 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using ETV6 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated WB ETV6 Antibody (Center) (ABIN658417) western blot analysis in mouse lung tissue lysates (35 µg/lane). This demonstrates the ETV6 antibody detected the ETV6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ETV6 Antibody (N-term) (ABIN652863) in K562 cell line lysates (35 µg/lane). ETV6 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with ETV6 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to ETV6 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml] ETV6 monoclonal antibody (M01), clone 3B10 Western Blot analysis of ETV6 expression in Jurkat . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

ETV6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)


Mouse (Murine) ,


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Top referenced anti-ETV6 Antibodies

  1. Human Monoclonal ETV6 Primary Antibody for IHC (p), ELISA - ABIN560810 : Meester-Smoor, Janssen, ter Haar, van Wely, Aarnoudse, van Oord, van Tilburg, Zwarthoff: The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation. in PLoS ONE 2011 (PubMed)
    Show all 2 references for ABIN560810

  2. Human Polyclonal ETV6 Primary Antibody for IF, ELISA - ABIN1533723 : Golub, Barker, Lovett, Gilliland: Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. in Cell 1994 (PubMed)
    Show all 2 references for ABIN1533723

  3. Chicken Polyclonal ETV6 Primary Antibody for WB - ABIN2792591 : Rubnitz, Wichlan, Devidas, Shuster, Linda, Kurtzberg, Bell, Hunger, Chauvenet, Pui, Camitta, Pullen: Prospective analysis of TEL gene rearrangements in childhood acute lymphoblastic leukemia: a Children's Oncology Group study. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 (PubMed)

  4. Chicken Polyclonal ETV6 Primary Antibody for IHC, WB - ABIN2792592 : Schick, Oakeley, Hynes, Badache: TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against ETV6 Interaction Partners

Zebrafish Ets Variant 6 (ETV6) interaction partners

  1. Dominant-negative truncated ETV6 with deletions of the ETS (show ETS1 Antibodies) domain or the PNT (show ETS2 Antibodies) domain interfered with repression by full-length ETV6 and affected expression of early hematopoietic and erythroid markers in embryos.

  2. the transcriptional repressor Tel plays an evolutionarily conserved role in angiogenesis: it is indispensable for the sprouting of human endothelial cells and for normal development of the Danio rerio blood circulatory system

Human Ets Variant 6 (ETV6) interaction partners

  1. The study shows a low representation of ETV6-RUNX1 (show RUNX1 Antibodies) fusion oncogenes among pediatric acute lymphoblastic leukemia patients from King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.

  2. the ETV6-NTRK3 fusion (show NTRK3 Antibodies) might identify a subset of gastrointestinal stromal tumours with peculiar clinicopathological characteristics

  3. our results demonstrate that MIR181A1 and ETV6/RUNX1 (show RUNX1 Antibodies) regulate each other, and we propose that a double negative loop involving MIR181A1 and ETV6/RUNX1 (show RUNX1 Antibodies) may contribute to ETV6/RUNX1 (show RUNX1 Antibodies)-driven arrest of differentiation in pre-B ALL.

  4. germline ETV6 mutations associated with leukemia and thrombocytopenia were identifies in multiple individuals. Mutant ETV6 showed decreased ability to regulate expression of other genes.

  5. We observed significant enrichment of the neuroactive ligand-receptor interaction pathway in TCF3 (show TCF3 Antibodies)-PBX1 (show PBX1 Antibodies) as well as an enrichment of genes involved in immunity and infection pathways in ETV6-RUNX1 (show RUNX1 Antibodies) subtype

  6. Our study demonstrated that ETV6 was markedly involved in the development of non-small cell lung cancer and could serve as a potential prognostic marker for this deadly disease

  7. Suggest germline ETV6 variations as the basis of a novel genetic syndrome associated with predisposition to childhood acute lymphoblastic leukemia.

  8. Molecular analysis of ETV6 gene rearranged mammary analogue secretory carcinoma of salivary glands tumors with lack of classical ETV6-NTRK3 fusion (show NTRK3 Antibodies).

  9. the ETV6/ARG oncoprotein contributes to autonomous cell growth by compensating for the requirement of growth factor through activating STAT5 (show STAT5A Antibodies) signaling, which leads to the up-regulation of c-Myc (show MYC Antibodies).

  10. TEL-AML1 (show RUNX1 Antibodies) fusion protein blocks B-cell differentiation and downregulates the IRF3 (show IRF3 Antibodies)-IFNalpha/beta pathway by modulating expression and phosphorylation of IRF3 (show IRF3 Antibodies) in human primary hematopoietic precursor cells.

Mouse (Murine) Ets Variant 6 (ETV6) interaction partners

  1. ETV6 DNA binding inhibition is established by the stability of its inhibitory helix

  2. Studied the combination of Etv6-RUNX1 (show RUNX1 Antibodies) and Pax5 (show PAX5 Antibodies)(+/-) alleles, they generated a transplantable B220 (show PTPRC Antibodies) + CD19 (show CD19 Antibodies)+ B-ALL with a significant disease incidence; RNA-seq analysis showed a gene expression pattern consistent with arrest at the pre-B stage.

  3. In murine models of B-cell progenitors, evidence found that ETV6- RUNX1 (show RUNX1 Antibodies) alters the expression of cytoskeletal regulatory genes, resulting in a block of the CDC42 (show CDC42 Antibodies) signaling pathway, and compromises the chemotactic response to CXCL12 (show CXCL12 Antibodies).

  4. ETV6-SAM (show TTN Antibodies) domain interface mutations block ETV6-NTRK3 (show NTRK3 Antibodies)-induced cellular transformation

  5. the autoinhibition of ETV6 DNA binding by sequences C-terminal to its ETS (show ETS1 Antibodies) domain

  6. find that both IRS1 (show IRS1 Antibodies) and kinase active IGF1R (show IGF1R Antibodies) are required for ETV6-NTRK3 (show NTRK3 Antibodies) transformation, that tyrosine phosphorylated IRS1 (show IRS1 Antibodies) is present in high molecular weight complexes with EN and IGF1R (show IGF1R Antibodies), and that EN colocalizes with IGF1R (show IGF1R Antibodies) at the plasma membrane

  7. Cytogenetic study of 33 children with ETV6-RUNX1 (show RUNX1 Antibodies) positive acute lymphoblastic leukemia predict long term survival.

  8. TEL binding to IRF-8 (show IRF8 Antibodies) for recruitment of HDAC3 (show HDAC3 Antibodies) is regulated by gamma-interferon (show IFNG Antibodies)

  9. the ability of TEL to repress transcription and suppress growth is regulated by sumoylation and nuclear export

  10. nucleo-cytoplasmic delocalization of the major isoform of TEL-ETV6 is regulated by V-src (show SRC Antibodies)

ETV6 Antigen Profile

Protein Summary

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Gene names and symbols associated with anti-Ets Variant 6 (ETV6) Antibodies

  • ets variant gene 6 (TEL oncogene) (etv6) antibody
  • ets variant 6 (ETV6) antibody
  • ets variant 6 (etv6) antibody
  • ets variant 6 (LOC100352251) antibody
  • ets variant 6 (Etv6) antibody
  • ets variant gene 6 (TEL oncogene) (Etv6) antibody
  • ets variant gene 6 (TEL oncogene) (ETV6) antibody
  • AW123102 antibody
  • AW557856 antibody
  • etv-6 antibody
  • id:ibd2308 antibody
  • Tel antibody
  • TEL/ABL antibody

Protein level used designations for anti-Ets Variant 6 (ETV6) Antibodies

transcription factor ETV6 , ztel , ets variant gene 6 (TEL oncogene) , TEL oncogene , ets variant 6 , ETS translocation variant 6 , ETS-related protein Tel1 , TEL1 oncogene , translocation-ets-leukemia , ets domain protein

GENE ID SPECIES
114444 Danio rerio
473366 Pan troglodytes
486685 Canis lupus familiaris
549634 Xenopus (Silurana) tropicalis
100063341 Equus caballus
100352251 Oryctolagus cuniculus
2120 Homo sapiens
312777 Rattus norvegicus
504512 Bos taurus
14011 Mus musculus
395750 Gallus gallus
Selected quality suppliers for anti-ETV6 (ETV6) Antibodies
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