anti-Euchromatic Histone Methyltransferase 1 (EHMT1) Antibodies

The protein encoded by EHMT1 is a histone methyltransferase that is part of the E2F6 complex, which represses transcription.

list all antibodies Gene Name GeneID UniProt
EHMT1 79813 Q9H9B1
EHMT1    
EHMT1    
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Top anti-EHMT1 Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using GLP mouse mAb against GLP recombinant protein. 100 μL Log in to see 2 to 3 Days
$345.40
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$343.75
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$446.88
Details
Human Mouse Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
All Species Mouse Un-conjugated ELISA   0.1 mg Log in to see 8 to 11 Days
$408.19
Details
Human Mouse Alexa Fluor 680 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Mouse Alexa Fluor 750 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Mouse Un-conjugated ELISA, WB   100 μL Log in to see 11 to 16 Days
$512.29
Details
Human Mouse Un-conjugated WB   0.1 mg Log in to see 2 to 6 Days
$326.00
Details
Human Goat Un-conjugated ELISA   100 μL Log in to see 16 Days
$376.60
Details

EHMT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Rat (Rattus)


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All Species


Top referenced anti-EHMT1 Antibodies

  1. Human Monoclonal EHMT1 Primary Antibody for ELISA, WB - ABIN969480 : De León, Crutchlow, Ham, Stoffers: Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus. in The international journal of biochemistry & cell biology 2006 (PubMed)
    Show all 2 references for 969480

More Antibodies against EHMT1 Interaction Partners

Human Euchromatic Histone Methyltransferase 1 (EHMT1) interaction partners

  1. missense variants in EHMT1 that lead to protein misfolding and disrupted histone mark binding can lead to Kleefstra Syndrome [case reports]

  2. we find an estrogen receptor (show ESR1 Antibodies)-independent synthetic lethal interaction between a GATA3 (show GATA3 Antibodies) frameshift mutant with an extended C-terminus and the histone methyltransferases G9A (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies), indicating perturbed epigenetic regulation

  3. Selective degradation of the mutant EHMT1 mRNA leads to Kleefstra syndrome.

  4. G9a (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies) are required for stable maintenance of imprinted DNA methylation (show HELLS Antibodies) in embryonic stem cells.

  5. the clinical picture we found in Norwegian patients with Kleefstra syndrome is similar to the findings described in the literature. An interesting point is that in the literature >85% of the patients have a deletion of 9q34.3 and the remaining have a mutation in the EHMT1 gene, whereas in this study we found 50% with a deletion, and 50% with a mutation.

  6. Data indicate zinc finger proteins ZNF644 (show ZNF644 Antibodies) and WIZ (show ZNF803 Antibodies) as two core subunits in the histone-lysine N-methyltransferase G9a (show EHMT2 Antibodies)/GLP (show RCBTB1 Antibodies) complex, and interact with the transcription activation domain of G9a (show EHMT2 Antibodies) and GLP (show RCBTB1 Antibodies).

  7. data provide genetic and pharmacologic evidence that EHMT1 and EHMT2 (show EHMT2 Antibodies) are epigenetic regulators involved in gamma-globin (show HBG1 Antibodies) repression and represent a novel therapeutic target for SCD (show SCD Antibodies).

  8. The expression level of EHMT1 and EHMT2 (show EHMT2 Antibodies) inversely correlates with the type I interferon (show IFNA Antibodies) responsiveness in chronic myeloid leukemia (show BCL11A Antibodies) cell lines.

  9. The current knowledge on the mechanisms of action and function of EHMT1, with particular emphasis on their interplay in the regulation of chromatin states and biological processes.

  10. Haploinsufficiency of EHMT1 caused by either microdeletions at 9q34.3 or intragenic mutations are associated with Kleefstra syndrome.

EHMT1 Antigen Profile

Protein Summary

The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EHMT1

  • euchromatic histone-lysine N-methyltransferase 1 (EHMT1) antibody
  • bA188C12.1 antibody
  • Eu-HMTase1 antibody
  • EUHMTASE1 antibody
  • FP13812 antibody
  • GLP antibody
  • GLP1 antibody
  • KMT1D antibody

Protein level used designations for EHMT1

G9a like protein , G9a-like protein 1 , H3-K9-HMTase 5 , histone H3-K9 methyltransferase 5 , histone-lysine N-methyltransferase EHMT1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5 , lysine N-methyltransferase 1D

GENE ID SPECIES
79813 Homo sapiens
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