You are viewing an incomplete version of our website. Please click to reload the website as full version.

Euchromatic Histone-Lysine N-Methyltransferase 1 Proteins (EHMT1)

The protein encoded by EHMT1 is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. Additionally we are shipping EHMT1 Antibodies (129) and EHMT1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EHMT1 77683 Q5DW34
EHMT1 79813 Q9H9B1
Rat EHMT1 EHMT1 362078  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top EHMT1 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

EHMT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) Interaction Partners

Mouse (Murine) Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) interaction partners

  1. The stress-induced Brg1 (show SMARCA4 Proteins)-G9a (show EHMT2 Proteins)/GLP-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 Proteins) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.

  2. data provide genetic and pharmacologic evidence that EHMT1 and EHMT2 (show EHMT2 Proteins) are epigenetic regulators involved in gamma-globin repression and represent a novel therapeutic target for SCD (show SCD Proteins).

  3. histone methyltransferase activities of GLP and G9a (show EHMT2 Proteins) are stimulated by neighboring nucleosomes that are premethylated at H3K9

  4. Prdm16 (show PRDM16 Proteins) was required in young mice to suppress the expression of white-fat-selective genes in BAT (show BAAT Proteins) through recruitment of the histone methyltransferase Ehmt1.

  5. G9a and GLP have an essential role in normal morphogenesis of the atrioventricular septum through regulation of the size of the atrioventricular cushion.

  6. Reduced Euchromatin histone methyltransferase 1 (show DNMT1 Proteins) causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice.

  7. EHMT1 is an essential BAT (show BAAT Proteins)-enriched lysine methyltransferase in the PRDM16 (show PRDM16 Proteins) transcriptional complex and controls brown adipose cell fate

  8. These data demonstrate that Ehmt1 haploinsufficiency in mice leads to learning deficits and synaptic dysfunction, providing a possible mechanism for the ID phenotype in patients with Kleefstra syndrome

  9. Metallothionein 1 (show MT1 Proteins) h tumour suppressor activity in prostate cancer is mediated by euchromatin methyltransferase 1 (show DNMT1 Proteins).

  10. EHMT1 protein binds to nuclear factor-kappaB p50 (show NFKB1 Proteins) and represses gene expression.

Human Euchromatic Histone-Lysine N-Methyltransferase 1 (EHMT1) interaction partners

  1. Data indicate zinc finger proteins ZNF644 and WIZ as two core subunits in the histone-lysine N-methyltransferase G9a/GLP complex, and interact with the transcription activation domain of G9a and GLP.

  2. data provide genetic and pharmacologic evidence that EHMT1 and EHMT2 (show EHMT2 Proteins) are epigenetic regulators involved in gamma-globin (show HBG1 Proteins) repression and represent a novel therapeutic target for SCD (show SCD Proteins).

  3. The expression level of EHMT1 and EHMT2 (show EHMT2 Proteins) inversely correlates with the type I interferon (show IFNA Proteins) responsiveness in chronic myeloid leukemia (show BCL11A Proteins) cell lines.

  4. The current knowledge on the mechanisms of action and function of EHMT1, with particular emphasis on their interplay in the regulation of chromatin states and biological processes.

  5. Haploinsufficiency of EHMT1 caused by either microdeletions at 9q34.3 or intragenic mutations are associated with Kleefstra syndrome.

  6. PRC2 and G9a/GLP interact physically and functionally.

  7. Data indicate that Kleefstra syndrome patient carrying a splice-site mutation in EHMT1 inherited from the mother who showed tissue-specific mosaicism.

  8. Results suggest that GLP may play a significant role in the maintenance of HIV-1 latency by catalyzing dimethylation of H3K9.

  9. EHMT1 protein binds to nuclear factor-kappaB p50 (show NFKB1 Proteins) and represses gene expression.

  10. Disruption of an EHMT1-associated chromatin-modification module causes intellectual disability.

EHMT1 Protein Profile

Protein Summary

The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EHMT1

  • euchromatic histone-lysine N-methyltransferase 1 (EHMT1)
  • euchromatic histone-lysine N-methyltransferase 1 (Ehmt1)
  • euchromatic histone-lysine N-methyltransferase 1 (ehmt1)
  • euchromatic histone-lysine N-methyltransferase 1 (LOC100217666)
  • euchromatic histone methyltransferase 1 (Ehmt1)
  • 9230102N17Rik protein
  • bA188C12.1 protein
  • D330003E03 protein
  • EHMT1 protein
  • Eu-HMTase1 protein
  • EUHMTASE1 protein
  • FP13812 protein
  • G9a protein
  • GLP protein
  • GLP1 protein
  • KMT1D protein
  • mKIAA1876 protein

Protein level used designations for EHMT1

euchromatic histone methyltransferase 1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5 , euchromatic histone-lysine N-methyltransferase 1 , histone-lysine N-methyltransferase EHMT1 , histone-lysine N-methyltransferase, H3 lysine-9 specific 5-like , G9a-like protein 1 , lysine N-methyltransferase 1D , G9a like protein , H3-K9-HMTase 5 , histone H3-K9 methyltransferase 5

GENE ID SPECIES
417250 Gallus gallus
464891 Pan troglodytes
491224 Canis lupus familiaris
528606 Bos taurus
100023838 Monodelphis domestica
100058869 Equus caballus
100078328 Ornithorhynchus anatinus
100121084 Nasonia vitripennis
100124713 Xenopus (Silurana) tropicalis
100217666 Taeniopygia guttata
100466861 Ailuropoda melanoleuca
100538392 Meleagris gallopavo
100565730 Anolis carolinensis
77683 Mus musculus
79813 Homo sapiens
362078 Rattus norvegicus
Selected quality suppliers for EHMT1 Proteins (EHMT1)
Did you look for something else?