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EEF1E1 encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. Additionally we are shipping EEF1E1 Proteins (10) and EEF1E1 Kits (2) and many more products for this protein.
Showing 10 out of 44 products:
analysis of the heterotetrameric complex structure of the glutathione transferase (GST (show SLCO6A1 Antibodies)) domains shared among the four MSC (show MSC Antibodies) components, methionyl-tRNA synthetase (MRS), glutaminyl-prolyl-tRNA synthetase (EPRS (show EPRS Antibodies)), AIMP2 (show AIMP2 Antibodies) and AIMP3
AIMP3 was shown to be involved in the cellular aging of human mesenchymal stem cells.
Identification of EEf1E1 and OBFC2B as novel BRCA1-partner genes in the DNA double-strand break repair pathway.
AIMP3 stabilizes and protects methionyl-tRNA synthetase and eIF2gamma (show EIF2S3 Antibodies) through the binding interactions.
AIMP3 is a critical mediator of Met-tRNA(i)(Met) transfer from methionyl-tRNA synthetase to eIF2 (show EIF2S1 Antibodies) complex for the accurate and efficient translation initiation
Data show that aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (show HSPB3 Antibodies) (AIMP3)/p18 is released from aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (show HSPB3 Antibodies) (AIMP3) by UV irradiation-induced stress.
Decreased expression of AIMP3 in gastric and colorectal cancer tissues suggests that down-regulation of this protein may be related to inactivation of the tumor suppressor functions of AIMP proteins and might play a role in the development of GC and CRC (show CALR Antibodies).
p18 (show CDKN2C Antibodies) is a haploinsufficient tumor suppressor and a key factor for ATM (show ATM Antibodies)/ATR (show ANTXR1 Antibodies)-mediated p53 (show TP53 Antibodies) activation.
analysis of the three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with
No EEF1E1 mutations were detected in human cancer specimens.
AIMP3 is a specific regulator of mature lamin A (show LMNA Antibodies) and imply that enhanced expression of AIMP3 might be a factor driving cellular and/or organismal aging [AIMP3]
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
eukaryotic translation elongation factor 1 epsilon 1
, eukaryotic translation elongation factor 1 epsilon-1
, ARS-interacting multifunctional protein 3
, aminoacyl tRNA synthetase complex-interacting multifunctional protein 3
, multisynthase complex auxiliary component p18
, p18 component of aminoacyl-tRNA synthetase complex
, elongation factor p18
, multisynthetase complex auxiliary component p18
, Elongation factor p18
, Multisynthase complex auxiliary component p18