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Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) ELISA Kits

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Additionally we are shipping EIF2S1 Antibodies (125) and EIF2S1 Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EIF2S1 13665 Q6ZWX6
EIF2S1 54318 P68101
EIF2S1 1965 P05198
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Top EIF2S1 ELISA Kits at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
1 kit Log in to see 9 Days
$714.29
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Rat
96 Tests Log in to see 16 to 21 Days
$999.43
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Monkey
96 Tests Log in to see 16 to 21 Days
$999.43
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Guinea Pig
96 Tests Log in to see 16 to 21 Days
$999.43
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Sheep
96 Tests Log in to see 16 to 21 Days
$999.43
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Mouse
96 Tests Log in to see 16 to 21 Days
$999.43
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Rabbit
96 Tests Log in to see 16 to 21 Days
$999.43
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Human
96 Tests Log in to see 16 to 21 Days
$999.43
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Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
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Cow
96 Tests Log in to see 16 to 21 Days
$999.43
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More ELISA Kits for EIF2S1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. Therapeutic modulation of eIF2alpha phosphorylation rescues TDP-43 (show TARDBP ELISA Kits) toxicity in amyotrophic lateral sclerosis disease models.

Mouse (Murine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. Data indicate that 5xFAD-related pathologies do not necessarily require hyperphosphorylation of eIF2alpha (show EIF2A ELISA Kits) to emerge.

  2. Endoplasmic reticulum stress suppressed CReP (show PPP1R15B ELISA Kits) expression in an IRE1 alpha (show ERN1 ELISA Kits)-dependent manner, which increased eIF2alpha (show EIF2A ELISA Kits) phosphorylation and consequently attenuated protein synthesis.

  3. eIF2alphaP acts as a molecular switch that dictates either cell survival or death by activated Akt (show AKT1 ELISA Kits) in response to oxidative stress.

  4. aberrant phosphorylation of eukaryotic initiation factor (show EIF4G1 ELISA Kits)-2a (eIF2a (show EIF2A ELISA Kits)) may induce synaptic failure and neurodegeneration through persistent translational inhibition of global protein synthesis.

  5. Alteration of protein homeostasis and eIF2alpha (show EIF2A ELISA Kits) phosphorylation status by pathogenic huntingtin (show HTT ELISA Kits) appears to be an important cause of striatal cell death.

  6. Data indicate that prolonged endoplasmic reticulum stress inhibits protein synthesis independently of translation initiation factor eIF2alpha (show EIF2A ELISA Kits)-P.

  7. This study demonistrated that Genetic deletion of eIF2alpha (show EIF2A ELISA Kits) kinase PERK (show EIF2AK3 ELISA Kits) prevented enhanced phosphorylation of eIF2alpha (show EIF2A ELISA Kits) and deficits in protein synthesis, synaptic plasticity and spatial memory in animal disease model of Alzheimer's disease.

  8. eIF2alpha (show EIF2A ELISA Kits) phosphorylation in the context of the ER stress response plays a role in cell survival by counteracting the p53 (show TP53 ELISA Kits)-mediated mitochondrial apoptosis in response to statins.

  9. eIF2a (show EIF2A ELISA Kits) is hyperphosphorylated in the cortex of aged mice. Young human-ApoE4 targeted-replacement mice show increased p-eIF2a/eIF2a (show EIF2A ELISA Kits) levels in both cortex and hippocampus.

  10. the induction of REDD1 (show DDIT4 ELISA Kits) gene expression was shown to require the protein kinase (show CDK7 ELISA Kits) PERK (show EIF2AK3 ELISA Kits) and enhanced phosphorylation of its substrate, the alpha-subunit (show POLG ELISA Kits) of eukaryotic initiation factor (show EIF4G1 ELISA Kits) 2.

Pig (Porcine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. In conclusion, the immediate-early (show JUN ELISA Kits) IE180 protein of pseudorabies virus has the previously uncharacterized ability to suppress phosphorylation levels of the eukaryotic translation initiation factor (show EIF2A ELISA Kits) eIF2alpha (show EIF2A ELISA Kits).

Human Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. Our work suggests that OLA1 (show OLA1 ELISA Kits) is a novel translational GTPase (show RACGAP1 ELISA Kits) and plays a suppressive role in translation and cell survival, as well as cancer growth and progression.

  2. a delay in eIF2-bound GTP (show AK3 ELISA Kits) hydrolysis should occur. In this work, we reconstructed this situation and found that such a delay leads to the redistribution of initiation complexes in favor to downstream AUG codons.

  3. The reactive oxygen species-generating NADPH oxidase-4 (Nox4 (show NOX4 ELISA Kits)) is induced downstream of ATF4 (show ATF4 ELISA Kits), binds to a PP1 (show PPA1 ELISA Kits)-targeting subunit GADD34 (show PPP1R15A ELISA Kits) at the endoplasmic reticulum, and inhibits PP1 (show PPA1 ELISA Kits) activity to increase eIF2alpha (show EIF2A ELISA Kits) phosphorylation and ATF4 (show ATF4 ELISA Kits) levels.

  4. Classical swine fever virus (CSFV) infection increased the phosphorylation of eukaryotic translation initiation factor (show EIF2A ELISA Kits) (eIF)2alpha and its kinase PKR (show PKLR ELISA Kits). The activation of PKR (show PKLR ELISA Kits) during CSFV infection is beneficial to the virus.

  5. eIF2alpha (show EIF2A ELISA Kits) phosphorylation plays a role in hypoxia-induced translational attenuation

  6. phosphorylation of eIF2alpha during early brain reperfusion is carried out by PERK, these findings suggest that there is prolonged activation of the unfolded protein response in the reperfused brain.

  7. Results indicate an evolutionary lineage of translation initiation factor eIF2alpha (show EIF2A ELISA Kits)/gamma from the functionally related elongation factor (show TSFM ELISA Kits) eEF1Balpha/eEF1A (show EEF1A1 ELISA Kits) complex.

  8. multiple domains in I-1 target cellular PP1 (show PPA1 ELISA Kits) complexes, and I-1 has a role as a cellular regulator of eIF2alpha (show EIF2A ELISA Kits) phosphorylation

  9. Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase.

  10. Our results demonstrate that Ebp1 (show NFKB1 ELISA Kits) is a new dsRNA-binding protein that acts as a cellular inhibitor of eIF2alpha (show EIF2A ELISA Kits) phosphorylation suggesting that it could be involved in protein translation control

Cow (Bovine) Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) interaction partners

  1. Caspase (show CASP3 ELISA Kits)(s)-dependent proteolysis of molecular chaperones and eIF2alpha (show EIF2A ELISA Kits) may be novel signaling pathways of apoptosis.

EIF2S1 Antigen Profile

Antigen Summary

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2\; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3\; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987

Gene names and symbols associated with EIF2S1

  • eukaryotic translation Initiation Factor 2alpha (eIF-2alpha) antibody
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (eif2s1) antibody
  • eukaryotic translation initiation factor 2 alpha subunit (LOC693063) antibody
  • eukaryotic translation initiation factor 2 alpha subunit (CNI00230) antibody
  • eukaryotic translation initiation factor 2 alpha subunit (THAPSDRAFT_105) antibody
  • Eukaryotic translation initiation factor 2 subunit 1 (if2a) antibody
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (LOC100339093) antibody
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (LOC100350462) antibody
  • eukaryotic translation initiation factor 2 subunit 1 (if2a) antibody
  • eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1) antibody
  • eukaryotic translation initiation factor 2, subunit 1 alpha (Eif2s1) antibody
  • eukaryotic translation initiation factor 2, subunit 1 alpha (LOC100155472) antibody
  • eukaryotic translation initiation factor 2, subunit 1 alpha b (eif2s1b) antibody
  • 35kDa antibody
  • 0910001O23Rik antibody
  • 2410026C18Rik antibody
  • CG9946 antibody
  • deIF2alpha antibody
  • Dmel\\CG9946 antibody
  • EIF-2 antibody
  • eIF-2 a antibody
  • eIF-2 alpha antibody
  • EIF-2A antibody
  • EIF-2alpha antibody
  • EIF2 antibody
  • eIF2 alpha antibody
  • eIF2-alpha antibody
  • EIF2A antibody
  • eIF2alpha antibody
  • eif2s1 antibody
  • elF2alpha antibody
  • fb19d01 antibody
  • IF2A_DROME antibody
  • l(1)14Cf antibody
  • l(1)19-153 antibody
  • M(1)8e3-10 antibody
  • M(1)14C antibody
  • M(1)19-153 antibody
  • wu:fb19d01 antibody

Protein level used designations for EIF2S1

CG9946-PA , eIF-2alpha-PA , eukaryotic initiation factor 2alpha , eukaryotic translation initiation factor 2 , eukaryotic translation initiation factor 2alpha , minute (1) 14C , EIF-2A , EIF-2alpha , eIF-2-alpha , eukaryotic translation initiation factor 2 subunit 1 , eukaryotic translation initiation factor 2 subunit alpha , eukaryotic translation initiation factor 2 alpha subunit , Eukaryotic translation initiation factor 2 subunit 1 , eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa , eIF-2A , eIF-2alpha , eukaryotic translation initiation factor 2A , eIF2 alpha subunit , eukaryotic translation initiation factor 2, subunit 1 (alpha )

GENE ID SPECIES
32617 Drosophila melanogaster
448087 Xenopus (Silurana) tropicalis
693063 Bombyx mori
3259501 Cryptococcus neoformans var. neoformans JEC21
7449310 Thalassiosira pseudonana CCMP1335
100195154 Salmo salar
100339093 Oryctolagus cuniculus
100350462 Oryctolagus cuniculus
100528138 Ictalurus punctatus
100587728 Nomascus leucogenys
13665 Mus musculus
54318 Rattus norvegicus
100155472 Sus scrofa
321564 Danio rerio
1965 Homo sapiens
380444 Xenopus laevis
423279 Gallus gallus
480361 Canis lupus familiaris
327694 Bos taurus
100174029 Pongo abelii
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