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Eukaryotic Translation Initiation Factor 2A, 65kDa Proteins (EIF2A)

EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002 [PubMed 12133843]).[supplied by OMIM, Mar 2008].. Additionally we are shipping EIF2A Antibodies (64) and EIF2A Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EIF2A 229317 Q8BJW6
Rat EIF2A EIF2A 502531  
EIF2A 83939 Q9BY44
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Top EIF2A Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

EIF2A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) Interaction Partners

Mouse (Murine) Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

  1. in mouse skeletal muscle stem cells, general repression of translation, mediated by the phosphorylation of translation initiation factor (show TIF1 Proteins) eIF2alpha at serine 51 (P-eIF2alpha), is required to maintain the quiescent state

  2. Skeletal muscle-specific (show EIF3K Proteins) eukaryotic translation initiation factor 2alpha (show EIF2S1 Proteins) phosphorylation controls amino acid metabolism and fibroblast growth factor 21 (show FGF21 Proteins)-mediated non-cell-autonomous energy metabolism.

  3. These experiments connect embryonic stem cell growth factors to eIF2alpha phosphorylation.

  4. PGRN (show GRN Proteins) is a key regulator of insulin (show INS Proteins) resistance and PGRN (show GRN Proteins) may mediate its effects, at least in part, by inducing ER stress via the PERK (show EIF2AK3 Proteins)-eIF2alpha dependent pathway

  5. The CARE-LUC mouse model represents an innovative tool to investigate the eIF2alpha-ATF4 (show ATF4 Proteins) axis and to develop drugs targeting this important pathway in the remediation of related pathologies.

  6. inhibition of eIF2alpha and FAK (show PTK2 Proteins) signaling may play an important role in cigarette smoking-induced lung EC apoptosis and emphysema

  7. eIF2a phosphorylation is required for the normal function of intestinal Paneth cells and mucosal homeostasis.

  8. Hypothalamic eIF2alpha phosphorylation could play a critical role in the onset of anorexia associated with certain diseases.

  9. The pathogenesis of cardiomyopathy in Frederich ataxia (show USP14 Proteins) correlates with the early and persistent eIF2alpha phosphorylation.

  10. data underscore the local, innate, pro-inflammatory nature of the response to Clostridium difficile and highlight eIF2alpha phosphorylation and the unfolded protein response

Zebrafish Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

  1. Both DrPKZ-A and DrPKZ-B isoforms functionally interact with eIF2alpha and inhibit protein synthesis in Danio rerio.

Human Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) interaction partners

  1. The Newcastle disease virus-induced translation shutoff at late infection times was attributed to sustaining phosphorylation of eIF2a (show EIF2S1 Proteins), which is mediated by continual activation of PKR (show PKLR Proteins) and degradation of PP1 (show PPA1 Proteins).

  2. We identified EIF2A (show EIF2S1 Proteins) phosphorylation as a novel early molecular event occurring in response to NAMPT (show NAMPT Proteins) inhibition and mediating protein synthesis arrest.

  3. These experiments connect embryonic stem cell growth factors to eIF2alpha phosphorylation.

  4. analysis of the ER stress response in immunogenic cell death and the potential value of eIF2alpha phosphorylation as a biomarker for this clinically relevant variant of apoptosis [review]

  5. The data highlight independent interactions of PP1 (show PPA1 Proteins) and eIF2alpha with GADD34 (show PPP1R15A Proteins), demonstrating that GADD34 (show PPP1R15A Proteins) functions as a scaffold both in vitro and in cells

  6. hypusine-eIF5A (show EIF5 Proteins)-facilitated translation elongation promotes arsenite-induced polysome disassembly and stress granule assembly in cells subjected to adverse environmental conditions

  7. There was no statistically significant difference in IFN therapeutic effectiveness among the patients with different genotypes of eIF-2a (show EIF2S1 Proteins)-reg2 (show FLOT1 Proteins).

  8. ABC50 (show ABCF1 Proteins) N-terminal region interacts with eukaryotic initiation factor (show EIF4G1 Proteins) eIF2 (show EIF2S1 Proteins) and is a target for regulatory phosphorylation by CK2 (show CSNK2A1 Proteins)

EIF2A Protein Profile

Protein Summary

EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002

Gene names and symbols associated with EIF2A

  • eukaryotic translation initiation factor 2A, 65kDa (EIF2A)
  • eukaryotic translation initiation factor (eif2A)
  • eukaryotic translation initiation factor (EIF2A)
  • eukaryotic translation initiation factor 2A, 65kDa (eif2a)
  • eukaryotic translation initiation factor 2A (Eif2a)
  • eukaryotic translation initiation factor 2A (eif2a)
  • eukaryotic translation initiation factor 2A, 65kDa (Eif2a)
  • D030048D22 protein
  • D3Ertd194e protein
  • EIF-2A protein
  • EIF2A protein
  • eif2alpha protein
  • im:7145971 protein
  • MST089 protein
  • MSTP004 protein
  • MSTP089 protein
  • zgc:110460 protein

Protein level used designations for EIF2A

eukaryotic translation initiation factor 2A, 65kDa , eukaryotic translation initiation factor , eukaryotic translation initiation factor 2A-like , eIF-2A , 65 kDa eukaryotic translation initiation factor 2A , eukaryotic translation initiation factor 2A

GENE ID SPECIES
470965 Pan troglodytes
710497 Macaca mulatta
9625673 Volvox carteri f. nagariensis
9681594 Micromonas pusilla CCMP1545
100050507 Equus caballus
100145715 Xenopus (Silurana) tropicalis
100398797 Callithrix jacchus
100481938 Ailuropoda melanoleuca
229317 Mus musculus
502531 Rattus norvegicus
573991 Danio rerio
83939 Homo sapiens
477112 Canis lupus familiaris
100622221 Sus scrofa
614746 Bos taurus
101119523 Ovis aries
100338417 Oryctolagus cuniculus
100721181 Cavia porcellus
398445 Xenopus laevis
425042 Gallus gallus
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