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Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) ELISA Kits

EIF2B1 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Additionally we are shipping Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Antibodies (36) and Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse EIF2B1 EIF2B1 209354 Q99LC8
Anti-Rat EIF2B1 EIF2B1 64514 Q64270
Anti-Human EIF2B1 EIF2B1 1967 Q14232
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More ELISA Kits for Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa Interaction Partners

Mouse (Murine) Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) interaction partners

  1. These are the first data that mechanistically link eIF2Bepsilon (show EIF2B5 ELISA Kits) abundance to skeletal myofibre hypertrophy.

  2. A point mutation in translation initiation factor eIF2B (show EIF2B4 ELISA Kits) leads to Vanishing White Matter disease.

  3. Inhibition of pancreatic protein synthesis in this model of acute pancreatitis most likely results from inhibition of translation initiation from increased eIF2alpha (show EIF2A ELISA Kits) phosphorylation, reduction of eIF2B (show EIF2B4 ELISA Kits) activity, and inhibition of eIF4F (show EIF4A2 ELISA Kits) complex formation.

Human Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) interaction partners

  1. Oligodendrocytes with truncated or deletion mutants eIF2B showed less tolerable to endoplasmic reticulum stress

  2. These data emphasize the importance of eIF2Balpha in mediating the eIF2 (show EIF2S1 ELISA Kits) kinase translation-inhibitory activity and may provide insight into the complex nature of vesiculovirus oncolysis.

  3. mutational analysis of the eIF2B genes of patients with an antenatal- or early-infantile-onset encephalopathy and an early demise

  4. Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B activity.

  5. analysis of novel mutations in patients with eIF2B-related disorders

  6. Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon)

  7. The authors suspected VWM and sequenced the genes EIF2B1-5, which revealed one heterozygous mutation in EIF2B4 (show EIF2B4 ELISA Kits).

  8. Crystal structure of the alpha subunit of human translation initiation factor 2B.

Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1) Antigen Profile

Antigen Summary

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Gene names and symbols associated with EIF2B1

  • translation initiation factor eIF-2B alpha subunit (eIF2b1) antibody
  • translation initiation factor eIF-2B subunit alpha (PGTG_05021) antibody
  • Translation initiation factor eIF-2B subunit alpha (ei2ba) antibody
  • translation initiation factor eif-2b subunit alpha (ei2ba) antibody
  • eukaryotic translation initiation factor 2B, subunit 1 (alpha) (Eif2b1) antibody
  • eukaryotic translation initiation factor 2B, subunit 1 alpha (Eif2b1) antibody
  • eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa (EIF2B1) antibody
  • 26kDa antibody
  • D5Ertd406e antibody
  • DDBDRAFT_0219393 antibody
  • DDBDRAFT_0231375 antibody
  • DDB_0219393 antibody
  • DDB_0231375 antibody
  • eIF-2a antibody
  • EIF2B antibody
  • EIF2BA antibody

Protein level used designations for EIF2B1

translation initiation factor eIF-2B subunit alpha , Translation initiation factor eIF-2B subunit alpha , translation initiation factor eif-2b subunit alpha , eIF-2B GDP-GTP exchange factor subunit alpha , eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa) , GTP-exchange protein , eIF-2Balpha

GENE ID SPECIES
8626881 Dictyostelium discoideum AX4
10530886 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100305173 Oncorhynchus mykiss
100528837 Ictalurus punctatus
209354 Mus musculus
64514 Rattus norvegicus
1967 Homo sapiens
516670 Bos taurus
100172592 Pongo abelii
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