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Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa Proteins (EIF2B4)

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. Additionally we are shipping EIF2B4 Antibodies (55) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EIF2B4 13667 Q61749
Rat EIF2B4 EIF2B4 117019 Q63186
EIF2B4 8890 Q9UI10
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Top EIF2B4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

EIF2B4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) Interaction Partners

Human Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) interaction partners

  1. A novel missense mutation within EIF2B4 is associated with vanishing white matter disease.

  2. demonstrate that DAP5 associates with eIF2beta and eIF4AI to stimulate IRES-dependent translation of cellular mRNAs

  3. The functional effects of selected vanishing white matter disease mutations in EIF2B2 (show EIF2B2 Proteins)-5 by coexpressing mutated and wild-type subunits in human cells.

  4. analysis of developmental splicing deregulation in leukodystrophies related to EIF2B (show EIF2B1 Proteins) mutations

  5. A mutation .626G>A [p.Arg209Gln] in exon 7 and c.1399C>T [p.Arg467Trp] in exon 13 of the EIF2B4-Gens.

  6. Data demonstrate that cellular response resulting from eIF2alpha (show EIF2A Proteins) phosphorylation is attenuated in several cancer cell lines, and correlates with the expression of a specific isoform of a regulatory eIF2B (show EIF2B1 Proteins) subunit, eIF2Bdelta variant 1 (V1).

  7. These results validate the measurement of eIF2B (show EIF2B1 Proteins) GEF (show SLC2A4RG Proteins) activity in patients' transformed-lymphocytes as an important tool for the diagnosis of eIF2B (show EIF2B1 Proteins)-related disorders.

  8. A unique EIF2B (show EIF2B1 Proteins) mutation spectrum in Chinese Vanishing white matter patients was shown.

  9. Mutation in EIF2B4 causes childhood ataxia (show USP14 Proteins) with central nervous system hypomyelination/ vanishing white matter leukodystrophy.

  10. We report for the first time that in vitro fertilization and embryo transfer can lead to a successful procreation in patients with OLD related to EIF2B (show EIF2B1 Proteins) mutations.

EIF2B4 Protein Profile

Protein Summary

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EIF2B4

  • eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa (EIF2B4)
  • eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa (eif2b4)
  • eukaryotic translation initiation factor 2B, subunit 4 delta (eif2b4)
  • eIF2B GDP-GTP exchange factor (eIF2b4)
  • eukaryotic translation initiation factor 2B, subunit 4 delta (Eif2b4)
  • translation initiation factor eIF-2B-delta (EIF-2B-DELTA)
  • DDBDRAFT_0189067 protein
  • DDBDRAFT_0232421 protein
  • DDB_0189067 protein
  • DDB_0232421 protein
  • EIF-2B protein
  • EIF2B protein
  • EIF2B4 protein
  • EIF2BD protein
  • EIF2Bdelta protein
  • MGC146592 protein
  • si:ch211-101l18.4 protein
  • wu:fb54a09 protein
  • zgc:110790 protein

Protein level used designations for EIF2B4

eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa , translation initiation factor eIF-2B subunit delta , translation initiation factor eIF2B delta subunit , translation initiation factor eIF-2B subunit delta-like , eIF-2B GDP-GTP exchange factor subunit delta , eukaryotic translation initiation factor 2B subunit 4 delta , translation initiation factor eIF-2b delta subunit

GENE ID SPECIES
425800 Gallus gallus
459099 Pan troglodytes
475702 Canis lupus familiaris
496301 Xenopus laevis
541548 Danio rerio
700322 Macaca mulatta
779817 Xenopus (Silurana) tropicalis
8627814 Dictyostelium discoideum AX4
100055283 Equus caballus
100412065 Callithrix jacchus
100441987 Pongo abelii
100580961 Nomascus leucogenys
13667 Mus musculus
117019 Rattus norvegicus
8890 Homo sapiens
521926 Bos taurus
100009560 Oryctolagus cuniculus
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