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Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) ELISA Kits

EIF2B5 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Additionally we are shipping EIF2B5 Antibodies (26) and EIF2B5 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse EIF2B5 EIF2B5 224045 Q8CHW4
Anti-Rat EIF2B5 EIF2B5 192234 Q64350
Anti-Human EIF2B5 EIF2B5 8893 Q13144
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More ELISA Kits for EIF2B5 Interaction Partners

Mouse (Murine) Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) interaction partners

  1. analysis of eukaryotic initiation factor 2B epsilon phosphorylation sites and ubiquitin-modified lysine residues

  2. Data show that toll (show TLR4 ELISA Kits)-like receptors (TLRs)-TRIF (show RNF138 ELISA Kits) signalling activates eIF2B (show EIF2B4 ELISA Kits) GEF (show ARHGEF2 ELISA Kits) through PP2A-mediated serine dephosphorylation of the eIF2B (show EIF2B4 ELISA Kits) varepsilon-subunit.

  3. mouse model of EIF2B (show EIF2B4 ELISA Kits)-related leukodystrophy; findings provide evidence that hypomorphic Eif2b5 alleles lead to delayed and abnormal development and maintenance of CNS white matter

  4. Inhibition of pancreatic protein synthesis in this model of acute pancreatitis most likely results from inhibition of translation initiation from increased eIF2alpha (show EIF2A ELISA Kits) phosphorylation, reduction of eIF2B (show EIF2B4 ELISA Kits) activity, and inhibition of eIF4F (show EIF4A2 ELISA Kits) complex formation.

  5. inactivation of glycogen synthase kinase 3beta (GSK3beta) by high glucose and high insulin (show INS ELISA Kits) induces increase in synthesis of laminin beta1 via activation of eIF2Bepsilon.

Human Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5) interaction partners

  1. This study demonstrated that no evidence for a role of Ile587Val polymorphism of EIF2B5 gene in multiple sclerosis in Kashmir Valley if India.

  2. Patient exhibits an early-infantile onset and progressive disease course resembling Cree leukoencephalopathy, suggesting a severe functional disruption of eIF2Bepsilon caused by R195H as well as by I408T mutations.

  3. Missense mutations in EIF2B5 are associated with multiple sclerosis.

  4. Also a mutation c.1913G>A[p.Arg638 His] in exon 14 of the EIF2B5-Gens as single nucleotide polymorphism.

  5. crystal structure of the guanine nucleotide exchange factor for elf2

  6. Functional analysis of recently identified mutations in eukaryotic translation initiation factor (show EIF2A ELISA Kits) 2Bepsilon (eIF2Bepsilon) identified in Chinese patients with vanishing white matter disease

  7. Cree leukoencephalopathy and CACH/VWM disease are allelic at the EIF2B5 locus.

  8. Mutation in EIF2B5 causes childhood ataxia (show USP14 ELISA Kits) with central nervous system hypomyelination/ vanishing white matter leukodystrophy.

  9. We demonstrated that mutations in the gene EIF2B5 cause "leukoencephalopathy with vanishing white matter." This gene encodes one of the five subunits of the translation factor eIF2B (show EIF2B1 ELISA Kits).

  10. Biochemical analyses indicate that mutations analyzed in eIF2Balpha and -epsilon reduce the steady-state level of the affected subunit, while the most severe mutant tested, eIF2Bbeta(V341D), forms complexes with reduced stability and lower eIF2B (show EIF2B1 ELISA Kits) activity.

EIF2B5 Antigen Profile

Antigen Summary

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Gene names and symbols associated with EIF2B5

  • eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa (EIF2B5) antibody
  • trimeric LpxA-like enzyme (AT2G34970) antibody
  • trimeric LpxA-like enzyme (AT3G02270) antibody
  • translation initiation factor eif-2b epsilon subunit (AOR_1_624154) antibody
  • translation initiation factor eIF-2B epsilon subunit (CTRG_05484) antibody
  • translation initiation factor eIF-2B epsilon subunit (PAAG_05066) antibody
  • translation initiation factor eIF-2B epsilon subunit (CGB_A5380C) antibody
  • translation initiation factor eif-2b epsilon subunit (TERG_01115) antibody
  • eukaryotic translation initiation factor 2B, subunit 5 epsilon (Eif2b5) antibody
  • AO090003000364 antibody
  • C81315 antibody
  • CACH antibody
  • CLE antibody
  • EIF-2B antibody
  • EIF2B5 antibody
  • EIF2Bepsilon antibody
  • F14P3.8 antibody
  • F14P3_8 antibody
  • F19I3.20 antibody
  • F19I3_20 antibody
  • LVWM antibody

Protein level used designations for EIF2B5

eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa , translation initiation factor eIF-2B subunit epsilon , translation initiation factor eIF-2B subunit epsilon-like , translation initiation factor eIF-2B epsilon subunit , translation initiation factor eif-2b epsilon subunit , eIF-2B GDP-GTP exchange factor subunit epsilon , initiation factor eIF-2Be , eIF-2Bepsilon

GENE ID SPECIES
424948 Gallus gallus
460881 Pan troglodytes
488103 Canis lupus familiaris
703673 Macaca mulatta
783760 Bos taurus
100389722 Callithrix jacchus
100446186 Pongo abelii
100580454 Nomascus leucogenys
818061 Arabidopsis thaliana
821200 Arabidopsis thaliana
5991536 Aspergillus oryzae RIB40
8300542 Candida tropicalis MYA-3404
9096172 Paracoccidioides sp. 'lutzii' Pb01
10187846 Cryptococcus gattii WM276
10373875 Trichophyton rubrum CBS 118892
224045 Mus musculus
192234 Rattus norvegicus
8893 Homo sapiens
100009393 Oryctolagus cuniculus
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