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anti-Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) Antibodies

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. Additionally we are shipping EIF3A Kits (5) and EIF3A Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF3A 8661 Q14152
EIF3A 13669 P23116
EIF3A 292148 Q1JU68
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Top anti-EIF3A Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB EIF3A Antibody (C-term) (ABIN656879) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB CU002 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CU002 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CU002 antibody detected the CU002 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, WB Immunofluorescence analysis of methanol-fixed A431, using AP22367PU-N EIF3A antibody at 1/200 dilution. Immunohistochemical analysis of paraffin-embedded Hepatoma, using AP22367PU-N EIF3A antibody at 1/500 dilution. 0.1 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-EIF3A AntibodyTitration: 1.0 µg/mL  Positive Control: Hela Whole Cell  There is BioGPS gene expression data showing that EIF3A is expressed in HeLa 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (34.36 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-EIF3 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101301 dilution 10 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human breast carcinoma labeled with Anti eIF3A Polyclonal Antibody, Unconjugated (ABIN704891) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

EIF3A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-EIF3A Antibodies

  1. Human Polyclonal EIF3A Primary Antibody for EIA, WB - ABIN952046 : Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007 (PubMed)
    Show all 4 references for ABIN952046

  2. Human Polyclonal EIF3A Primary Antibody for IHC (p), WB - ABIN656879 : Enchev, Schreiber, Beuron, Morris: Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3. in Structure (London, England : 1993) 2010 (PubMed)
    Show all 2 references for ABIN656879

  3. Human Polyclonal EIF3A Primary Antibody for ELISA, WB - ABIN563740 : Kroczynska, Kaur, Katsoulidis, Majchrzak-Kita, Sassano, Kozma, Fish, Platanias: Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals. in Molecular and cellular biology 2009 (PubMed)

More Antibodies against EIF3A Interaction Partners

Human Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) interaction partners

  1. Collybistin (show Arhgef9 Antibodies) forms a complex with mTOR (show FRAP1 Antibodies) and eIF3 and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism.

  2. eIF3 has a role in controlling cell size independently of S6K1 (show RPS6KB1 Antibodies)-activity

  3. eIF3a (show EIF6 Antibodies) improves ovarian cancer patients' response to cisplatin-based chemotherapy by down regulating XPC (show XPC Antibodies) and p27(Kip1 (show CDKN1B Antibodies)).

  4. eIF3a (show EIF6 Antibodies) SNPs are significantly correlated with platinum-based chemotherapy toxicities in Chinese non-small cell lung carcinoma patients.

  5. Data conclude that eIF3a (show EIF6 Antibodies) expression may have a profound effect on the urinary bladder cancer phenotype and, in addition, may serve as a prognostic marker for low grade UBCs.

  6. Taken together, these results show that Neurospora crassa eIF3 provides a tractable system for probing the structure and function of human-like eIF3 in the context of living cells.

  7. Of the total, the deregulation of several genes (CDK1 (show CDK1 Antibodies), CDK2 (show CDK2 Antibodies), CDK4 (show CDK4 Antibodies), MCM2 (show MCM2 Antibodies), MCM3 (show MCM3 Antibodies), MCM4 (show MCM4 Antibodies), EIF3a (show EIF6 Antibodies) and RPN2 (show PSMD1 Antibodies)) were potentially associated with disease development and progression.

  8. At 37 degrees C, P185(HER2 (show ERBB2 Antibodies)) internalized through coated pits and vesicles and concentrated in the endosomes and multivesicular bodies in the cells of both cell lines, as well as in lysosomes in cells BT-474

  9. findings suggested altered eIF3a (show EIF6 Antibodies) expression closely correlated with p27 (show PAK2 Antibodies) status, and the association was of prognostic value for resected NSCLC

  10. eIF3a (show EIF6 Antibodies) and eIF3c (show EIF3C Antibodies) control abundance and assembly of the entire eIF3 and thus represent its crucial scaffolding elements critically required for formation of preinitiation complexes.

Mouse (Murine) Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A) interaction partners

  1. The pleiotropic mouse phenotype extra-toes spotting (show EIF3C Antibodies) is caused by translation initiation factor Eif3c (show EIF3C Antibodies) mutations.

  2. May play some roles in development and differentiation; decreased eIF3a expression may be a pre-requisite of intestinal epithelial cell differentiation.

  3. Stable expression of a truncated eIF3e (show EIF3E Antibodies) in NIH 3T3 cells causes malignant transformation

  4. eIF3a expression oscillated with cell cycle and peaked in S phase. Reducing eIF3a expression also reduced cell proliferation rate by elongating cell cycle but did not change the cell cycle distribution.

EIF3A Antigen Profile

Protein Summary

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Gene names and symbols associated with EIF3A

  • eukaryotic translation initiation factor 3, subunit A (EIF3A) antibody
  • eukaryotic translation initiation factor 3 subunit A (eif3a) antibody
  • eukaryotic translation initiation factor 3, subunit 10 (theta) (eif3s10) antibody
  • eukaryotic translation initiation factor 3, subunit A (Eif3a) antibody
  • A830012B05Rik antibody
  • Csma antibody
  • Eif3 antibody
  • eIF3-p170 antibody
  • eIF3-theta antibody
  • Eif3s10 antibody
  • EIF6 antibody
  • mKIAA0139 antibody
  • P167 antibody
  • p180 antibody
  • p185 antibody
  • TIF32 antibody
  • wu:fi15c03 antibody
  • zgc:66194 antibody
  • zgc:77263 antibody
  • ZH12 antibody

Protein level used designations for EIF3A

eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa , eukaryotic translation initiation factor 6 , Eukaryotic translation initiation factor 3 subunit 10 , eIF-3-theta , eIF3a , eukaryotic translation initiation factor 3 subunit 10 , eukaryotic translation initiation factor 3 subunit A , EIF3, p180 subunit , centrosomin homolog , cytoplasmic protein p167 , eIF3 p167 , eIF3 p180 , eIF3 p185 , eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD) , eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD) , eukaryotic translation initiation factor 3, subunit 10, 170kD , EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN) , centrosomin , eukaryotic translation initiation factor 3, subunit 10 (theta) , p162

GENE ID SPECIES
100066047 Equus caballus
466216 Pan troglodytes
443632 Xenopus laevis
327515 Danio rerio
8661 Homo sapiens
13669 Mus musculus
423927 Gallus gallus
486914 Canis lupus familiaris
506564 Bos taurus
292148 Rattus norvegicus
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