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Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) ELISA Kits

The protein encoded by EIF4G1 is a component of the multi-subunit protein complex EIF4F. Additionally we are shipping Eukaryotic Translation Initiation Factor 4 Gamma, 1 Antibodies (129) and Eukaryotic Translation Initiation Factor 4 Gamma, 1 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human EIF4G1 EIF4G1 1981 Q04637
Anti-Rat EIF4G1 EIF4G1 287986  
Anti-Mouse EIF4G1 EIF4G1 208643 Q6NZJ6
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More ELISA Kits for Eukaryotic Translation Initiation Factor 4 Gamma, 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) interaction partners

  1. Phosphorylation of 4E-BP1 (show EIF4EBP1 ELISA Kits) impairs the competition with eIF4G for eIF4E (show EIF4E ELISA Kits) binding.

  2. The eIF4G knockdown did not affect male fertility.

  3. Data show that in the early embryo dFMRP (show FMR1 ELISA Kits) associates specifically with Caprin, and with eIF4G, a key regulator of translational initiation.

  4. A novel eIF4G homolog, Off-schedule, couples translational control to meiosis and differentiation in Drosophila spermatocytes.

Arabidopsis thaliana Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) interaction partners

  1. coordinated and selective recruitment of eIF4E (show EIF4E ELISA Kits) and eIF4G factors at a very early step in potyvirus infection

Human Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) interaction partners

  1. EIF4G1 mutations are not related to Parkinson's disease

  2. VPS35 (show vps35 ELISA Kits) D620N and EIF4G1 R1205H mutations are not a common cause of Parkinson disease in the Greek population.

  3. This study is the first to directly assess the relative contribution of eIF4F (show EIF4A2 ELISA Kits) components to the expressed cellular proteome, transcription factors, microRNAs, and phenotype in multiple myeloma

  4. EIF4GI shares this activity and also interacts with eIF1 (show EIF1 ELISA Kits).

  5. the C-terminal extension (motif 3) is critical to 4E-BP1 (show EIF4EBP1 ELISA Kits)-mediated cell cycle arrest and it partially overlaps with the binding site of 4EGI-1

  6. EIF4G1 is neither a strong nor a common risk factor for Parkinson's disease: evidence from large European cohorts.

  7. This study therefore implicates c-Myc (show MYC ELISA Kits) as a potential regulator of the cancer-promoting effects of equol via up-regulation of eIF4GI and selective initiation of translation on mRNAs that utilize non-canonical initiation, including certain oncogenes

  8. Knockdown of eIF4GI was deleterious to myeloma cells phenotype and expression of specific molecular targets (SMAD5 (show SMAD5 ELISA Kits)/ERalpha (show ESR1 ELISA Kits)/HIF1alpha (show HIF1A ELISA Kits)/c-Myc (show MYC ELISA Kits)).

  9. in a generic cell model, new insights into the mechanisms whereby the FSH receptor (show FSHR ELISA Kits) controls translation have been gained. Rapamycin-sensitive eIF4G phosphorylation at the 5' cap may be a surrogate for the classical exchange between eIF4G and 4E-BP1 (show EIF4EBP1 ELISA Kits).

  10. The results of this study did not identify novel or previously reported pathogenic mutations (including the p.A502V and p.R1205H mutants) within EIF4G1 in the Japanese population.

Mouse (Murine) Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) interaction partners

  1. Our studies reveal unexpected genetic and functional interactions between VPS35 (show vps35 ELISA Kits) and EIF4G1, two seemingly unrelated PD genes, and functionally connect them to alpha-synuclein (show SNCA ELISA Kits) pathobiology in yeast, worms, and mouse.

  2. Disruption of insulin receptor (IR (show INSR ELISA Kits)) expression in beta cells has a direct impact on the expression of the convertase enzyme carboxypeptidase E (CPE (show CPE ELISA Kits)) by inhibition of the eukaryotic translation initiation factor (show EIF2A ELISA Kits) Eif4g1.

  3. Data indicate that MNK2 (show MKNK2 ELISA Kits) plays a unique role, not shared by its closest paralog MNK1 (show MKNK1 ELISA Kits), in limiting protein translation through its negative effect on eIF4G Ser1108 phosphorylation and p70S6K (show RPS6KB1 ELISA Kits) activation.

  4. expression of 3e5 diminishes eIF4G interaction with eIF3 (show EIF3A ELISA Kits) and causes abnormal gene expression at the translational level.

  5. findings assign NAD(P)H (show NQO1 ELISA Kits) quinone-oxydoreductase 1 an original role in the regulation of mRNA translation via the control of eIF4GI stability by the proteasome.

  6. downregulated expression in T cells following treatment with bis (show BAG3 ELISA Kits)(tri (show VANGL2 ELISA Kits)-n-butylin)oxide (TBTO), an immunotoxic organotin compound

  7. eIF4G binding to Mnk (show ATP7A ELISA Kits) is inhibted by Mnk1 (show MKNK1 ELISA Kits) phosphorylation by caspase (show CASP3 ELISA Kits)-activated Pak2/gamma-PAK (show PAK2 ELISA Kits)

  8. Comparison of the p53 (show TP53 ELISA Kits)-induced patterns of eIF4GI and 4E-BP1 (show EIF4EBP1 ELISA Kits) dephosphorylation and cleavage with those caused by the mammalian target of rapamycin (show FRAP1 ELISA Kits) inhibitor rapamycin

  9. These findings suggest that the ability of cells to rephosphorylate 4E-BP1 (show EIF4EBP1 ELISA Kits), resynthesise eIF4GI and restore the rate of protein synthesis after inactivation of p53 (show TP53 ELISA Kits) is an important aspect of recovery following the relief of physiological stress.

  10. interactions between Pdcd4 (show PDCD4 ELISA Kits) and components of the translation initiation complex, namely, the RNA helicase eIF4A (show EIF4A1 ELISA Kits) and the scaffolding protein eIF4G

Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Gene names and symbols associated with EIF4G1

  • eukaryotic translation initiation factor 4 gamma, 1 (EIF4G1) antibody
  • eukaryotic translation initiation factor 4G (eIF4G) antibody
  • zgc:158450 (zgc:158450) antibody
  • eukaryotic translation initiation factor 4 gamma, 1 (eif4g1) antibody
  • eukaryotic translation initiation factor 4G (EIF4G) antibody
  • eukaryotic initiation factor (EIF4G) antibody
  • eukaryotic translation initiation factor 4 gamma (eIF4g) antibody
  • eukaryotic translation initiation factor 4 gamma (Eif4g) antibody
  • eukaryotic translation initiation factor 4 gamma, 1 (Eif4g1) antibody
  • eukaryotic translation initiation factor 4, gamma 1 (Eif4g1) antibody
  • CG10811 antibody
  • CUCUMOVIRUS MULTIPLICATION 2 antibody
  • CUM2 antibody
  • DDBDRAFT_0217646 antibody
  • DDBDRAFT_0217647 antibody
  • DDBDRAFT_0234257 antibody
  • DDB_0217646 antibody
  • DDB_0217647 antibody
  • DDB_0234257 antibody
  • deIF4G antibody
  • Dmel\\CG10811 antibody
  • E030015G23Rik antibody
  • eIF-4G antibody
  • EIF-4G1 antibody
  • EIF4F antibody
  • eif4g antibody
  • EIF4G1 antibody
  • eIF4GI antibody
  • eukaryotic translation initiation factor 4G antibody
  • NV18824 antibody
  • p200 antibody
  • p220 antibody
  • PARK18 antibody
  • wu:fb50a05 antibody
  • wu:fc60b06 antibody

Protein level used designations for EIF4G1

eukaryotic translation initiation factor 4 gamma 1 , CG10811-PA , CG10811-PB , CG10811-PC , Eukaryotic-initiation-factor-4G , eIF-4G , eIF4G-PA , eIF4G-PB , eIF4G-PC , eukaryotic initiation factor 4G , translation initiation factor , translation initiation factor eIF4G , eukaryotic translation initiation factor 4 gamma, 1 , fb50a05 , eukaryotic initiation factor , eukaryotic translation initiation factor 4 gamma , eukaryotic translation initiation factor 4 gamma 1-like , EIF4-gamma , eIF-4-gamma 1 , eucaryotic translation initiation factor 4G , eIF-4G 1 , eIF-4G1

GENE ID SPECIES
449528 Sus scrofa
100033975 Equus caballus
43839 Drosophila melanogaster
424953 Gallus gallus
460888 Pan troglodytes
572435 Danio rerio
704923 Macaca mulatta
733162 Xenopus laevis
825194 Arabidopsis thaliana
5718605 Chlamydomonas reinhardtii
8246969 Micromonas sp. RCC299
8619923 Dictyostelium discoideum AX4
9688587 Micromonas pusilla CCMP1545
100083863 Ornithorhynchus anatinus
100115514 Nasonia vitripennis
100391519 Callithrix jacchus
100470670 Ailuropoda melanoleuca
1981 Homo sapiens
100009384 Oryctolagus cuniculus
287986 Rattus norvegicus
208643 Mus musculus
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