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Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) ELISA Kits

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. Additionally we are shipping EIF4G2 Antibodies (108) and EIF4G2 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human EIF4G2 EIF4G2 1982 P78344
Anti-Mouse EIF4G2 EIF4G2 13690 Q62448
Anti-Rat EIF4G2 EIF4G2 361628  
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More ELISA Kits for EIF4G2 Interaction Partners

Zebrafish Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

Xenopus laevis Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

Human Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

  1. Knockdown of EIF4G2 recapitulated the effects of mir (show MLXIP ELISA Kits)-139, whereas restoring EIF4G2 expression rescued the mir (show MLXIP ELISA Kits)-139 phenotype. elevated miR (show MLXIP ELISA Kits)-139-5p expression is associated with a favorable outcome in acute myeloid leukemia (show BCL11A ELISA Kits).

  2. findings provide the first mechanistic insights into the function of DAP5 as a selective regulator of cap-independent translation

  3. Our results provide evidence that the tumor suppressor effect of miR-520c-3p is mediated through repression of translation while inducing senescence and that eIF4GII is a key effector of this anti-tumor activity.

  4. DAP5, a translation initiation factor shown to positively regulate the translation of various internal ribosome entry sites containing mRNAs, promotes internal ribosome entry site-driven translation of p53 (show TP53 ELISA Kits) mRNA.

  5. DAP5/p97 and DAP5/p86 enhanced the translation of the anti-apoptotic protein Bcl-2 (show BCL2 ELISA Kits) and inhibited cisplatin-induced apoptosis

  6. Multiple isoforms of eIF4GII arise from multiple promoters & alternative splicing events. A non-canonical CUG initiation codon extends the eIF4GII N-terminus. The eIF4GII N-terminus plays an alternative role in initiation factor assembly.

  7. crystal structure of C-terminal region (residues 540-897) of p97/EIF4G2 (at 2.0 Angstrom resolution): sequence/structure homology with EIF4G1 (show EIF4G1 ELISA Kits)

  8. crystallization and preliminary X-ray diffraction analysis of the MIF4G domain of DAP5 is presented.

  9. The caspase (show CASP3 ELISA Kits)-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins

  10. proteolytic activity of HIV-1 protease on eIF4GI and eIF4GII and its implications for the translation of mRNAs

Mouse (Murine) Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

  1. analysis of the tandem MA-3 (show PDCD6 ELISA Kits) region of Pdcd4 (show PDCD4 ELISA Kits) protein and characterization of its interactions with eIF4A (show EIF4A1 ELISA Kits) and eIF4G (show EIF4G1 ELISA Kits)

EIF4G2 Antigen Profile

Antigen Summary

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3\; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Gene names and symbols associated with EIF4G2

  • eukaryotic translation initiation factor 4, gamma 2b (eif4g2b) antibody
  • eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2) antibody
  • eIF4G-related protein NAT1 (nat1) antibody
  • eukaryotic translation initiation factor 4, gamma 2 (Eif4g2) antibody
  • AA589388 antibody
  • AAG1 antibody
  • DAP-5 antibody
  • DAP5 antibody
  • E130105L11Rik antibody
  • EIF4G2 antibody
  • hm:zeh1307 antibody
  • Nat1 antibody
  • NAT1B antibody
  • Natm1 antibody
  • P97 antibody
  • wu:fa14h01 antibody
  • wu:fb44h01 antibody
  • wu:fb59c06 antibody
  • wu:fc21b05 antibody

Protein level used designations for EIF4G2

eukaryotic translation initiation factor 4 gamma, 2 , fb44h01 , eukaryotic translation initiation factor 4 gamma 2 , Eukaryotic translation initiation factor 4 gamma 2 , DAP-5 , aging-associated protein 1 , death-associated protein 5 , eIF-4-gamma 2 , eIF-4G 2 , eIF4G 2 , eukaryotic translation initiation factor 4G-like 1 , eIF4G-related protein NAT1 , p97 , novel APOBEC-1 target 1 , translation repressor NAT1 , translation repressor Nat1

GENE ID SPECIES
334618 Danio rerio
466443 Pan troglodytes
705510 Macaca mulatta
100173304 Pongo abelii
496405 Xenopus laevis
1982 Homo sapiens
395905 Gallus gallus
476854 Canis lupus familiaris
286870 Bos taurus
100009236 Oryctolagus cuniculus
13690 Mus musculus
361628 Rattus norvegicus
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