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Eukaryotic Translation Initiation Factor 4A2 Proteins (EIF4A2)

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. Additionally we are shipping EIF4A2 Antibodies (95) and EIF4A2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EIF4A2 1974 Q14240
EIF4A2 13682 P10630
Rat EIF4A2 EIF4A2 303831 Q5RKI1
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Top EIF4A2 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 1 mg Log in to see 7 to 9 Days
$1,842.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,129.50
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,129.50
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,129.50
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,131.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EIF4A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Eukaryotic Translation Initiation Factor 4A2 (EIF4A2) Interaction Partners

Human Eukaryotic Translation Initiation Factor 4A2 (EIF4A2) interaction partners

  1. Studies indicate a developing focus on targeting eukaryotic initiation factor 4A (show DDX39 Proteins) eIF4A1 (show EIF4A1 Proteins) and eIF4A2 as cancer therapy.

  2. These data support a linear model for miRNA-mediated gene regulation in which translational repression via eIF4A2 is required first, followed by mRNA destabilization.

  3. The results indicated that eIF4AI and eIF4AII expression are linked and that the two protein isoforms exhibit functional differences.

  4. Studies indicate that eIF4A (DDX2), together with its accessory proteins eIF4B and eIF4H, is thought to act as a helicase that unwinds secondary structures in the mRNA 5' UTR.

  5. Single nucleotide polymorphisms in two relevant candidate genes for glucose homeostasis, kininogen (KNG1 (show KNG1 Proteins)), and eukaryotic translation initiation factor (show EIF2A Proteins) 4alpha2 (EIF4A2) linked to type 2 diabetes.

  6. subcellular distribution of eIF4F components may potentiate the complex assembly

  7. A feedforward loop involving c-Myc (show MYC Proteins) and eIF4F that serves to link transcription and translation and that could contribute to the effects of c-Myc (show MYC Proteins) on cell proliferation and neoplastic growth.

Pig (Porcine) Eukaryotic Translation Initiation Factor 4A2 (EIF4A2) interaction partners

  1. complete sequence of the porcine EIF4A2 gene, its predicted amino acid sequence, genomic structure, expression patterns, and single nucleotide polymorphisms

EIF4A2 Protein Profile

Protein Summary

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Gene names and symbols associated with EIF4A2

  • eukaryotic translation initiation factor 4A2 (eif4a2)
  • eukaryotic translation initiation factor 4A2 (EIF4A2)
  • eukaryotic translation initiation factor 4A, isoform 2 (EIF4A2)
  • eukaryotic translation initiation factor 4A2 (LOC100220237)
  • eukaryotic translation initiation factor 4A2 (LOC100230686)
  • eukaryotic translation initiation factor 4A, isoform 2 (eif4a2)
  • eukaryotic translation initiation factor 4A2 (Eif4a2)
  • 4833432N07Rik protein
  • BM-010 protein
  • Ddx2b protein
  • eIF-4A-II protein
  • Eif4 protein
  • EIF4A protein
  • eIF4A-II protein
  • EIF4A2 protein
  • EIF4AII protein
  • EIF4F protein
  • wu:fd50g11 protein
  • xeif4aii protein
  • zgc:63783 protein

Protein level used designations for EIF4A2

eukaryotic initiation factor 4A-II , eukaryotic translation initiation factor 4A , eukaryotic translation initiation factor 4A2 , eukaryotic translation initiation factor 4A, isoform 2 , protein synthesis initiation factor 4AII , ATP-dependent RNA helicase eIF4A-2 , eIF-4A-II , eIF4A-II , translational eukaryotic inititation factor 4AII

GENE ID SPECIES
379831 Xenopus laevis
460917 Pan troglodytes
707775 Macaca mulatta
100068164 Equus caballus
100124955 Xenopus (Silurana) tropicalis
100328965 Oryctolagus cuniculus
100220237 Taeniopygia guttata
100230686 Taeniopygia guttata
100598391 Nomascus leucogenys
406760 Danio rerio
395232 Gallus gallus
1974 Homo sapiens
488118 Canis lupus familiaris
100101928 Sus scrofa
286819 Bos taurus
13682 Mus musculus
303831 Rattus norvegicus
100173892 Pongo abelii
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