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anti-Eukaryotic Translation Initiation Factor 4B (EIF4B) Antibodies

Required for the binding of mRNA to ribosomes. Additionally we are shipping EIF4B Kits (6) and EIF4B Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF4B 1975 P23588
EIF4B 75705 Q8BGD9
EIF4B 300253  
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Top anti-EIF4B Antibodies at antibodies-online.com

Showing 10 out of 183 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-EIF4B Antibody Titration: 1.25ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of EIF4B (arrow) using rabbit polyclonal EIF4B Antibody (S422) (ABIN388670). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the EIF4B gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with EIF4B-S422, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$357.50
Details
Human Mouse Un-conjugated EIA, IF, WB 0.1 mg Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of HeLa cells using EIF4B mouse mAb (green) and negative control (red) . 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-EIF4B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: ACHN cell lysate WB Suggested Anti-EIF4B  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:12500  Positive Control: ACHN cell lysate  EIF4B is strongly supported by BioGPS gene expression data to be expressed in Human ACHN cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using eIF4B (Phospho-Ser422) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using eIF4B (Phospho-Ser422) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-EIF4B Antibody (Center) Pab (ABIN388669) in HepG2 cell line lysates (35 µg/lane). EIF4B(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of anti-EIF4B Antibody (Center) Pab (ABIN388669) in 293 cell line lysates transiently transfected with the EIF4B gene (2 µg/lane). EIF4B(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details

EIF4B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus)


Top referenced anti-EIF4B Antibodies

  1. Human Polyclonal EIF4B Primary Antibody for EIA, IHC (p) - ABIN357289 : Milburn, Hershey, Davies, Kelleher, Kaufman: Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif. in The EMBO journal 1990 (PubMed)
    Show all 3 references for ABIN357289

  2. Human Polyclonal EIF4B Primary Antibody for IHC (p), WB - ABIN401568 : Landry, Chrétien, Lambert, Hickey, Weber: Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells. in The Journal of cell biology 1989 (PubMed)
    Show all 3 references for ABIN401568

  3. Human Polyclonal EIF4B Primary Antibody for IHC (p), WB - ABIN388670 : Doepker, Hsu, Saffran, Smiley: Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H. in Journal of virology 2004 (PubMed)
    Show all 3 references for ABIN388670

  4. Human Monoclonal EIF4B Primary Antibody for EIA, IF - ABIN1107074 : Mokas, Mills, Garreau, Fournier, Robert, Arya, Kaufman, Pelletier, Mazroui: Uncoupling stress granule assembly and translation initiation inhibition. in Molecular biology of the cell 2009 (PubMed)
    Show all 3 references for ABIN1107074

  5. Human Monoclonal EIF4B Primary Antibody for ICC, FACS - ABIN969517 : Shahbazian, Roux, Mieulet, Cohen, Raught, Taunton, Hershey, Blenis, Pende, Sonenberg: The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. in The EMBO journal 2006 (PubMed)
    Show all 2 references for ABIN969517

  6. Human Polyclonal EIF4B Primary Antibody for IHC (p), WB - ABIN401564 : Gingras, Raught, Sonenberg: Regulation of translation initiation by FRAP/mTOR. in Genes & development 2001 (PubMed)
    Show all 2 references for ABIN401564

  7. Cow (Bovine) Polyclonal EIF4B Primary Antibody for IHC, WB - ABIN2778771 : Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae. in Neurology 2004 (PubMed)
    Show all 2 references for ABIN2778771

More Antibodies against EIF4B Interaction Partners

Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 4B (EIF4B) interaction partners

  1. Data show that two functionally redundant isoforms of Drosophila eukaryotic initiation factor 4B are involved in cap-dependent translation, cell survival, and proliferation.

Human Eukaryotic Translation Initiation Factor 4B (EIF4B) interaction partners

  1. MicroRNA-216a inhibits the growth and metastasis of oral squamous cell carcinoma by targeting eIF4B.

  2. S6K1 (show RPS6KB1 Antibodies) enhances c-Myc (show MYC Antibodies) translation efficiency by modulating the phosphorylation of eukaryotic initiation factor (show EIF4G1 Antibodies) eIF4B, which is critical to unwind its structured 5' untranslated region.

  3. EIF4B, as a potentially key fragile point in EGFR (show EGFR Antibodies) and mTOR (show FRAP1 Antibodies) inhibitor synergy.

  4. eIF4B is the RSK (show RPS6KA1 Antibodies) downstream effector responsible for elevated Lamgamma2 as well as MYC (show MYC Antibodies) protein in neoplastic epithelial cells.

  5. The protein level of eukaryotic translation initiation factor 4B (eIF4B) was dramatically reduced in A549 cells as well as in the lung, spleen, and thymus of mice infected with influenza A virus.

  6. eIF4B-driven expression of these key survival proteins is directly correlated with patient outcome, and eIF4B, DAXX (show DAXX Antibodies) and ERCC5 (show ERCC5 Antibodies) are identified as novel prognostic markers for poor survival in DLBCL

  7. Report EIF4B binding within the IRES domain V of the coxsackie virus B3 mutant strain.

  8. Overexpression of pim-2 (show PIM2 Antibodies) may inhibit the apoptosis of prostate cancer cells through phosphorylation of eIF4B, thus promoting tumorigenesis.

  9. our results identify eIF4B as a critical substrate of Pim (show PIM1 Antibodies) kinases in mediating the activity of Abl (show ABL1 Antibodies) oncogenes

  10. ORF45/RSK (show RPS6KA1 Antibodies) axis-induced eIF4B phosphorylation is involved in translational regulation and is required for optimal KSHV lytic replication.

Mouse (Murine) Eukaryotic Translation Initiation Factor 4B (EIF4B) interaction partners

  1. PKR (show EIF2AK2 Antibodies) inhibition reduced the expression of eIF4B and C/EBPbeta (show CEBPB Antibodies) in an eIF2alpha (show EIF2A Antibodies)-independent manner

  2. Maintenance of eIF4E (show EIF4E Antibodies) interaction with eIF4G (show EIF4G1 Antibodies) was not by itself sufficient to sustain global rates of protein synthesis in the absence of mTORC1 signaling to p70S6K1 (show RPS6KB1 Antibodies); phosphorylation of both eIF4B and PDCD4 (show PDCD4 Antibodies) was additionally required.

  3. C-loops bind to eIF4B and prevent the factor's interaction with 18S rRNA of the small ribosomal subunit.

  4. Phosphorylation of eIF4B on Ser422 by p90 (show GPAM Antibodies) ribosomal protein S6 (show RPS6 Antibodies) kinase (show RPS6KB1 Antibodies) (RSK (show RPS6KA1 Antibodies)) and S6K (show RPS6KB1 Antibodies) is physiologically significant, as it increases the interaction of eIF4B with the eukaryotic translation initiation factor 3 (show EIF4E3 Antibodies).

  5. These data provide novel insights into complex multikinase regulation of eIF4B phosphorylation and reveal an important mechanism by which PKB (show AKT2 Antibodies) can regulate translation, potentially critical for the transforming capacity of this AGC (show ACAN Antibodies) kinase family member.

  6. Results establish critical roles for S6K (show RPS6KB1 Antibodies) and RSK (show RPS6KA1 Antibodies) in the induction of IFN-dependent biological effects and define a key regulatory role for eIF4B as a common mediator and integrator of IFN-generated signals from these kinases.

EIF4B Antigen Profile

Protein Summary

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Gene names and symbols associated with EIF4B

  • eukaryotic translation initiation factor 4B (EIF4B) antibody
  • eukaryotic initiation factor 4B (Eif4B) antibody
  • Eukaryotic initiation factor 4B (eIF-4B) antibody
  • eukaryotic translation initiation factor 4Bb (eif4bb) antibody
  • eukaryotic translation initiation factor 4B (eif4b) antibody
  • eukaryotic translation initiation factor 4Ba (eif4ba) antibody
  • eukaryotic translation initiation factor 4B (LOC100284982) antibody
  • Eukaryotic translation initiation factor 4B (if4b) antibody
  • eukaryotic translation initiation factor 4B (Eif4b) antibody
  • 2310046H11Rik antibody
  • AL024095 antibody
  • C85189 antibody
  • CG10837 antibody
  • DKFZp469D171 antibody
  • Dm-eIF4B antibody
  • Dmel\\CG10837 antibody
  • eIF-4b antibody
  • eIF-4B-L antibody
  • eIF-4B-S antibody
  • Eif4a2 antibody
  • EIF4B antibody
  • eIF4B-L antibody
  • eIF4B-S antibody
  • fb15c09 antibody
  • MGC89384 antibody
  • PRO1843 antibody
  • wu:fb15c09 antibody
  • zgc:101532 antibody

Protein level used designations for EIF4B

eukaryotic initiation factor 4B , CG10837-PA , CG10837-PB , CG10837-PE , CG10837-PF , eIF-4B-PA , eIF-4B-PB , eIF-4B-PE , eIF-4B-PF , eukaryotic translation initiation factor 4B , hypothetical protein , Eukaryotic translation initiation factor 4B , eIF-4B

GENE ID SPECIES
100061920 Equus caballus
543417 Triticum aestivum
3355041 Drosophila melanogaster
100401147 Callithrix jacchus
336619 Danio rerio
448618 Xenopus (Silurana) tropicalis
553214 Danio rerio
737509 Pan troglodytes
100037232 Xenopus laevis
100173344 Pongo abelii
100284982 Zea mays
100380867 Salmo salar
1975 Homo sapiens
505850 Bos taurus
75705 Mus musculus
300253 Rattus norvegicus
100858349 Gallus gallus
477600 Canis lupus familiaris
100735681 Cavia porcellus
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