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Eukaryotic Translation Initiation Factor 4B (EIF4B) ELISA Kits

Required for the binding of mRNA to ribosomes. Additionally we are shipping EIF4B Antibodies (183) and EIF4B Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EIF4B 1975 P23588
EIF4B 75705 Q8BGD9
Anti-Rat EIF4B EIF4B 300253  
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Top EIF4B ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$910.56
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Human
96 Tests Log in to see 2 to 3 Days
$480.00
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More ELISA Kits for EIF4B Interaction Partners

Fruit Fly (Drosophila melanogaster) Eukaryotic Translation Initiation Factor 4B (EIF4B) interaction partners

  1. Data show that two functionally redundant isoforms of Drosophila eukaryotic initiation factor 4B are involved in cap-dependent translation, cell survival, and proliferation.

Human Eukaryotic Translation Initiation Factor 4B (EIF4B) interaction partners

  1. MicroRNA-216a inhibits the growth and metastasis of oral squamous cell carcinoma by targeting eIF4B.

  2. S6K1 (show RPS6KB1 ELISA Kits) enhances c-Myc (show MYC ELISA Kits) translation efficiency by modulating the phosphorylation of eukaryotic initiation factor (show EIF4G1 ELISA Kits) eIF4B, which is critical to unwind its structured 5' untranslated region.

  3. EIF4B, as a potentially key fragile point in EGFR (show EGFR ELISA Kits) and mTOR (show FRAP1 ELISA Kits) inhibitor synergy.

  4. eIF4B is the RSK (show RPS6KA1 ELISA Kits) downstream effector responsible for elevated Lamgamma2 as well as MYC (show MYC ELISA Kits) protein in neoplastic epithelial cells.

  5. The protein level of eukaryotic translation initiation factor 4B (eIF4B) was dramatically reduced in A549 cells as well as in the lung, spleen, and thymus of mice infected with influenza A virus.

  6. eIF4B-driven expression of these key survival proteins is directly correlated with patient outcome, and eIF4B, DAXX (show DAXX ELISA Kits) and ERCC5 (show ERCC5 ELISA Kits) are identified as novel prognostic markers for poor survival in DLBCL

  7. Report EIF4B binding within the IRES domain V of the coxsackie virus B3 mutant strain.

  8. Overexpression of pim-2 (show PIM2 ELISA Kits) may inhibit the apoptosis of prostate cancer cells through phosphorylation of eIF4B, thus promoting tumorigenesis.

  9. our results identify eIF4B as a critical substrate of Pim (show PIM1 ELISA Kits) kinases in mediating the activity of Abl (show ABL1 ELISA Kits) oncogenes

  10. ORF45/RSK (show RPS6KA1 ELISA Kits) axis-induced eIF4B phosphorylation is involved in translational regulation and is required for optimal KSHV lytic replication.

Mouse (Murine) Eukaryotic Translation Initiation Factor 4B (EIF4B) interaction partners

  1. PKR (show EIF2AK2 ELISA Kits) inhibition reduced the expression of eIF4B and C/EBPbeta (show CEBPB ELISA Kits) in an eIF2alpha (show EIF2A ELISA Kits)-independent manner

  2. Maintenance of eIF4E (show EIF4E ELISA Kits) interaction with eIF4G (show EIF4G1 ELISA Kits) was not by itself sufficient to sustain global rates of protein synthesis in the absence of mTORC1 signaling to p70S6K1 (show RPS6KB1 ELISA Kits); phosphorylation of both eIF4B and PDCD4 (show PDCD4 ELISA Kits) was additionally required.

  3. C-loops bind to eIF4B and prevent the factor's interaction with 18S rRNA of the small ribosomal subunit.

  4. Phosphorylation of eIF4B on Ser422 by p90 (show GPAM ELISA Kits) ribosomal protein S6 (show RPS6 ELISA Kits) kinase (show RPS6KB1 ELISA Kits) (RSK (show RPS6KA1 ELISA Kits)) and S6K (show RPS6KB1 ELISA Kits) is physiologically significant, as it increases the interaction of eIF4B with the eukaryotic translation initiation factor 3 (show EIF4E3 ELISA Kits).

  5. These data provide novel insights into complex multikinase regulation of eIF4B phosphorylation and reveal an important mechanism by which PKB (show AKT2 ELISA Kits) can regulate translation, potentially critical for the transforming capacity of this AGC (show ACAN ELISA Kits) kinase family member.

  6. Results establish critical roles for S6K (show RPS6KB1 ELISA Kits) and RSK (show RPS6KA1 ELISA Kits) in the induction of IFN-dependent biological effects and define a key regulatory role for eIF4B as a common mediator and integrator of IFN-generated signals from these kinases.

EIF4B Antigen Profile

Antigen Summary

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Gene names and symbols associated with EIF4B

  • eukaryotic translation initiation factor 4B (EIF4B) antibody
  • eukaryotic initiation factor 4B (Eif4B) antibody
  • Eukaryotic initiation factor 4B (eIF-4B) antibody
  • eukaryotic translation initiation factor 4Bb (eif4bb) antibody
  • eukaryotic translation initiation factor 4B (eif4b) antibody
  • eukaryotic translation initiation factor 4Ba (eif4ba) antibody
  • eukaryotic translation initiation factor 4B (LOC100284982) antibody
  • Eukaryotic translation initiation factor 4B (if4b) antibody
  • eukaryotic translation initiation factor 4B (Eif4b) antibody
  • 2310046H11Rik antibody
  • AL024095 antibody
  • C85189 antibody
  • CG10837 antibody
  • DKFZp469D171 antibody
  • Dm-eIF4B antibody
  • Dmel\\CG10837 antibody
  • eIF-4b antibody
  • eIF-4B-L antibody
  • eIF-4B-S antibody
  • Eif4a2 antibody
  • EIF4B antibody
  • eIF4B-L antibody
  • eIF4B-S antibody
  • fb15c09 antibody
  • MGC89384 antibody
  • PRO1843 antibody
  • wu:fb15c09 antibody
  • zgc:101532 antibody

Protein level used designations for EIF4B

eukaryotic initiation factor 4B , CG10837-PA , CG10837-PB , CG10837-PE , CG10837-PF , eIF-4B-PA , eIF-4B-PB , eIF-4B-PE , eIF-4B-PF , eukaryotic translation initiation factor 4B , hypothetical protein , Eukaryotic translation initiation factor 4B , eIF-4B

GENE ID SPECIES
100061920 Equus caballus
543417 Triticum aestivum
3355041 Drosophila melanogaster
100401147 Callithrix jacchus
336619 Danio rerio
448618 Xenopus (Silurana) tropicalis
553214 Danio rerio
737509 Pan troglodytes
100037232 Xenopus laevis
100173344 Pongo abelii
100284982 Zea mays
100380867 Salmo salar
1975 Homo sapiens
505850 Bos taurus
75705 Mus musculus
300253 Rattus norvegicus
100858349 Gallus gallus
477600 Canis lupus familiaris
100735681 Cavia porcellus
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