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anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) Antibodies

EIF4EBP2 encodes a member of the eukaryotic translation initiation factor 4E binding protein family. Additionally we are shipping eIF4EBP2 Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF4EBP2 361845  
EIF4EBP2 1979 Q13542
EIF4EBP2 13688 P70445
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Top anti-eIF4EBP2 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB EIF4EBP2 Antibody (C-term) (ABIN1881292) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the EIF4EBP2 antibody detected the EIF4EBP2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Sample Type: HEK 293 cells (50ug)Primary Dilution: 1:1000Image Submitted by: Veronique DorvalLaval University, Canada . 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (32.34 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (32.71 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of EIF4EBP2 expression in transfected 293T cell line by EIF4EBP2 MaxPab polyclonal antibody.Lane 1: EIF4EBP2 transfected lysate(13.31 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details

EIF4EBP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-eIF4EBP2 Antibodies

  1. Human Polyclonal eIF4EBP2 Primary Antibody for WB - ABIN1881292 : Bidinosti, Martineau, Frank, Sonenberg: Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN1881292

More Antibodies against eIF4EBP2 Interaction Partners

Human Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) interaction partners

  1. mTORC1 controls mitochondrial activity and biogenesis by selectively promoting translation of nucleus-encoded mitochondria-related mRNAs via inhibition of the eukaryotic translation initiation factor 4E (eIF4E (show EIF4E Antibodies))-binding proteins (4E-BPs).

  2. Data show that the eIF4E (show EIF4E Antibodies) binding preference for 4E-BP2 over 4E-BP1 (show EIF4EBP1 Antibodies) is based on stacking of Arg63 side chain on Trp73 indole ring of eIF4E (show EIF4E Antibodies) and construction of hydrophobic space around the Trp73 indole ring by the Leu59-Leu60 sequence of 4E-BP2.

  3. isoaspartate formation repair modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain

  4. 4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin.

  5. Data show that H2O2 increased eIF4E (show EIF4E Antibodies) and 4E-BP1 (show EIF4EBP1 Antibodies) expression and eIF4E (show EIF4E Antibodies) phosphorylation, and shifted distribution of 4E-BP1 (show EIF4EBP1 Antibodies) phosphorylation. These oxidant-mediated alterations occur in concert with changes in factors known to regulate translation kinetics.

  6. PHAS-II, but not PHAS-III, contributes to the control of protein synthesis by insulin (show INS Antibodies)

  7. The C-terminal His74-Glu89 region of 4EBP2 acts as an auxiliary function for the major binding of Y(X)4L -binding motif (Tyr54-Leu60) to eIF4E (show EIF4E Antibodies).

  8. 4E-BPs regulate the stress granule localization of eIF4E (show EIF4E Antibodies)

Mouse (Murine) Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) interaction partners

  1. Data show that deletion of eukaryotic translation initiation factor 4E-binding protein 1/2 (4E-BP1/2) in erythroid cells rendered them resistant to mammalian target of rapamycin complex 1 (TORC1) inhibition and restored hemoglobin production.

  2. Disruption of genes encoding Eif4ebp1 (show EIF4EBP1 Antibodies) and Eif4ebp2 does not alter basal or sepsis-induced changes in skeletal muscle protein synthesis in male or female mice.

  3. 4E-BP1 (show EIF4EBP1 Antibodies)/2-null cells express less ATGL (show PNPLA2 Antibodies) and accumulate more fat than control cells, while knock down of Egr1 (show EGR1 Antibodies) in 4E-BP1 (show EIF4EBP1 Antibodies)/2-null cells increases ATGL (show PNPLA2 Antibodies) expression and decreases fat storage.

  4. translational control through 4E-BP2 represents a unique mechanism for selective regulation of AMPAR synthesis, synaptic function, and long-term plasticity, important for hippocampal-dependent memory processes.

  5. in the absence of 4E-BP proteins, mTORC1-mediated phosphorylation of p70S6K1 (show RPS6KB1 Antibodies) is elevated by a reduction in competition between the two substrates for interaction with raptor (show RPTOR Antibodies)

  6. isoaspartate formation repair modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain

  7. Two deamidation sites were mapped to an asparagine-rich sequence unique to 4E-BP2. Deamidated 4E-BP2 exhibits increased binding to the mammalian target of rapamycin (mTOR (show FRAP1 Antibodies))-binding protein raptor (show RPTOR Antibodies).

  8. These results, together with the fact that 4E-BPs are markedly induced during granulo-monocytic differentiation of myeloid cells in vitro, highlight the pivotal role of 4E-BP1 (show EIF4EBP1 Antibodies) and 4E-BP2 in the early phases of myelopoiesis

  9. 4E-BP2 plays a crucial role in proper regulation of the eIF4F (show EIF4A2 Antibodies) complex during long-term potentiation and learning and memory in the mouse hippocampus.

  10. The 4E-BP2 knockout mice demonstrated altered activity in the rotating rod test, light/dark exploration test, spontaneous alternation T-maze and conditioned taste aversion test.

eIF4EBP2 (EIF4EBP2) Antigen Profile

Protein Summary

This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.

Gene names and symbols associated with EIF4EBP2

  • eukaryotic translation initiation factor 4E binding protein 2 (eif4ebp2) antibody
  • eukaryotic translation initiation factor 4E binding protein 2 (Eif4ebp2) antibody
  • eukaryotic translation initiation factor 4E binding protein 2 (EIF4EBP2) antibody
  • eukaryotic initiation factor 4E (TcasGA2_TC012945) antibody
  • eukaryotic translation initiation factor 4E (Tb927.6.1870) antibody
  • eukaryotic translation initiation factor 4E (LmjF30.0450) antibody
  • eukaryotic translation initiation factor 4E binding protein 2 (LOC100342908) antibody
  • 4E-BP2 antibody
  • 4EBP2 antibody
  • 2810011I19Rik antibody
  • AA792569 antibody
  • BC010348 antibody
  • eIF-4E antibody
  • EIF4EBP2 antibody
  • MGC75579 antibody
  • MGC78987 antibody
  • PHAS-II antibody
  • PHASII antibody
  • Tb06.28P18.1010 antibody
  • wu:fa55e11 antibody
  • wu:fp45e09 antibody

Protein level used designations for EIF4EBP2

eukaryotic translation initiation factor 4E binding protein 2 , eukaryotic translation initiation factor 4E-binding protein 2 , fa55e11 , eukaryotic initiation factor 4E , eukaryotic translation initiation factor 4E , 4E-BP2 , eIF4E-binding protein 2 , phosphorylated, heat and acid stable regulated by insulin protein II , phosphorylated heat- and acid-stable protein regulated by insulin 2

GENE ID SPECIES
394958 Xenopus (Silurana) tropicalis
361845 Rattus norvegicus
386945 Danio rerio
414476 Xenopus laevis
489027 Canis lupus familiaris
658700 Tribolium castaneum
769479 Gallus gallus
782397 Bos taurus
3657825 Trypanosoma brucei brucei strain 927/4 GUTat10.1
5653570 Leishmania major strain Friedlin
100342908 Oryctolagus cuniculus
1979 Homo sapiens
13688 Mus musculus
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