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anti-Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) Antibodies

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.. Additionally we are shipping Eukaryotic Translation Initiation Factor 4E Family Member 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF4E2 9470 O60573
EIF4E2 363275  
EIF4E2 26987 Q8BMB3
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Top anti-Eukaryotic Translation Initiation Factor 4E Family Member 2 Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated WB EIF4E2 antibody   western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the EIF4E2  antibody detected the EIF4E2  protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-EIF4E2 Antibody Titration: 2.5ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated WB EIF4E2/MB10227 antibody  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the EIF4E2/MB10227  antibody detected the EIF4E2/MB10227 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-EIF4E2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate WB Suggested Anti-EIF4E2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: MCF7 cell lysate  EIF4E2 is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of EIF4E2 Antibody (N-term) polyclonal antibody(ABIN388676)(arrow). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the EIF4E2 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human breast carcinoma reacted with EIF4E2 Antibody (N-term)(ABIN388676), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image EIF4E2 antibody [N1C3] detects EIF4E2 protein at cytoplasm on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. EIF4E2 antibody [N1C3] , diluted at 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EIF4E2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-EIF4E2. Flow cytometric Analysis of Hela cells, using anti-EIF4E2 antibody (ABIN2454230), (Red), compared to a nonspecific negative control antibody, (Blue). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-EIF4E2 mouse monoclonal antibody. (ABIN2454245) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EIF4E2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-EIF4E2. 100 μL Log in to see 2 to 3 Days
$423.50
Details

EIF4E2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Rat (Rattus)


Mouse (Murine)


Top referenced anti-Eukaryotic Translation Initiation Factor 4E Family Member 2 Antibodies

  1. Human Monoclonal EIF4E2 Primary Antibody for WB - ABIN659115 : Watkins, Rukazenkov: Response to 'Clinical outcomes in NSCLC patients with EGFR mutations: pooled analysis'
(Paz-Ares et al., J Cell Mol Med. 2010; 14: 51-69). in Journal of cellular and molecular medicine 2010 (PubMed)
    Show all 4 references for ABIN659115

  2. Human Monoclonal EIF4E2 Primary Antibody for WB - ABIN659116 : Venkatesan, Rual, Vazquez, Stelzl, Lemmens, Hirozane-Kishikawa, Hao, Zenkner, Xin, Goh, Yildirim, Simonis, Heinzmann, Gebreab, Sahalie, Cevik, Simon, de Smet, Dann, Smolyar, Vinayagam, Yu et al.: An empirical framework for binary interactome mapping.... in Nature methods 2008 (PubMed)
    Show all 4 references for ABIN659116

  3. Human Polyclonal EIF4E2 Primary Antibody for EIA, IHC (p) - ABIN357298 : Rom, Kim, Gingras, Marcotrigiano, Favre, Olsen, Burley, Sonenberg: Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 references for ABIN357298

  4. Cow (Bovine) Polyclonal EIF4E2 Primary Antibody for IHC, WB - ABIN2778915 : Tee, Tee, Blenis: Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1. in FEBS letters 2004 (PubMed)
    Show all 2 references for ABIN2778915

More Antibodies against Eukaryotic Translation Initiation Factor 4E Family Member 2 Interaction Partners

Human Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) interaction partners

  1. Tristetraprolin (show ZFP36 Antibodies) recruits eukaryotic initiation factor (show EIF4G1 Antibodies) 4E2 (eIF4E2) to repress target mRNA translation.

  2. DNA damage induces an increase in ARIH1 (show ARIH1 Antibodies) protein levels and association of ARIH1 (show ARIH1 Antibodies) with 4EHP. In turn, this causes 4EHP recruitment to the mRNA cap, where it is known to compete with eIF4E.

  3. provide evidence that eIF4E2 binds 4E-T (show EIF4ENIF1 Antibodies) in the yeast two hybrid assay, as well as in pull-down assays and by recruitment to P-bodies in mammalian cells

  4. Activation of eIF4E2-directed translation is essential for cancer cells.

  5. GIGYF2 (show GIGYF2 Antibodies) and the zinc finger protein 598 (ZNF598 (show ZNF598 Antibodies)) are identified as components of the 4EHP complex.

  6. 4EHP over-expression instigates a negative feedback loop that inhibits upstream signaling to 4E-BP1 (show EIF4EBP1 Antibodies) and ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 Antibodies)) whereas the 4E-BP1 (show EIF4EBP1 Antibodies)-binding-deficient mutant of 4EHP(W95A) was unable to trigger this feedback loop

  7. ISGylation of 4EHP may play an important role in cap structure-dependent translation control in immune responses.

  8. 4EHP plays a physiological role utilizing both cap-binding and protein-binding functions but which is distinct from eIF4E (show EIF4E Antibodies).

  9. 4EHP binds cap analogs m(7)GpppG and m(7)GTP (show AK3 Antibodies) with low affinity

Mouse (Murine) Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) interaction partners

  1. DNA damage induces an increase in ARIH1 (show ARIH1 Antibodies) protein levels and association of ARIH1 (show ARIH1 Antibodies) with Eif4e2. In turn, this causes Eif4e2 recruitment to the mRNA cap, where it is known to compete with eIF4E (show EIF4E Antibodies).

  2. Data show that Prep1 and 4EHP co-localize in the cytosol of growing mouse oocytes, and that Prep1 binds the Hoxb4 (show HOXB4 Antibodies) 3'UTR (show UTS2R Antibodies) to inhibit its translation.[4EHP]

Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) Antigen Profile

Protein Summary

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Gene names and symbols associated with EIF4E2

  • eukaryotic translation initiation factor 4E family member 2 (EIF4E2) antibody
  • eukaryotic translation initiation factor 4E family member 2 (eif4e2) antibody
  • eukaryotic translation initiation factor 4E member 2 (eif4e2) antibody
  • eukaryotic translation initiation factor 4E family member 2 (LOC100221090) antibody
  • eukaryotic translation initiation factor 4E family member 2 (Eif4e2) antibody
  • eukaryotic translation initiation factor 4E member 2 (Eif4e2) antibody
  • 4E-LP antibody
  • 4EHP antibody
  • 2700069E09Rik antibody
  • AI036339 antibody
  • AV129531 antibody
  • D0H0S6743E antibody
  • EIF4E2 antibody
  • Eif4el3 antibody
  • id:ibd1007 antibody
  • IF4e antibody
  • MGC115622 antibody
  • zgc:110542 antibody
  • zgc:158544 antibody

Protein level used designations for EIF4E2

eukaryotic translation initiation factor 4E member 2 , eukaryotic translation initiation factor 4E-like 3 , eukaryotic translation initiation factor 4E family member 2 , eif4E-2A , eukaryotic translation initiation factor 4E type 2 , uncharacterized protein LOC575773 , eIF-4E type 2 , eIF4E type 2 , eIF4E-like cap-binding protein , eIF4E-like protein 4E-LP , eukaryotic translation initiation factor 4E homologous protein , mRNA cap-binding protein 4EHP , mRNA cap-binding protein type 3 , eukaryotic translation initiation factor 4E like 3 , eIF4E-2 , mRNA cap-binding protein type 2

GENE ID SPECIES
424941 Gallus gallus
460015 Pan troglodytes
488481 Canis lupus familiaris
541523 Danio rerio
548830 Xenopus (Silurana) tropicalis
575773 Strongylocentrotus purpuratus
713487 Macaca mulatta
734605 Xenopus laevis
781731 Bos taurus
100173976 Pongo abelii
100221090 Taeniopygia guttata
9470 Homo sapiens
100101924 Sus scrofa
519920 Bos taurus
363275 Rattus norvegicus
610238 Canis lupus familiaris
26987 Mus musculus
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