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Eukaryotic Translation Initiation Factor 4E Nuclear Import Factor 1 Proteins (EIF4ENIF1)

The protein encoded by EIF4ENIF1 is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. Additionally we are shipping EIF4ENIF1 Antibodies (86) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat EIF4ENIF1 EIF4ENIF1 305468  
EIF4ENIF1 56478 Q9NRA8
EIF4ENIF1 74203 Q9EST3
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Top EIF4ENIF1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

EIF4ENIF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Eukaryotic Translation Initiation Factor 4E Nuclear Import Factor 1 (EIF4ENIF1) Interaction Partners

Human Eukaryotic Translation Initiation Factor 4E Nuclear Import Factor 1 (EIF4ENIF1) interaction partners

  1. our data support a model where 4E-T promotes mRNA turnover by physically linking the 3'-terminal mRNA decay machinery to the 5' cap

  2. neural precursors are transcriptionally primed to generate neurons, but an eIF4E (show EIF4E Proteins)/4E-T complex sequesters and represses translation of proneurogenic proteins to determine appropriate neurogenesis.

  3. that while both eIF4E1 (show EIF4E Proteins) and eIF4E2 (show EIF4E2 Proteins) bind 4E-T via the canonical YX 4Lvarphi sequence, nearby downstream sequences also influence eIF4E (show EIF4E Proteins):4E-T interactions

  4. This work has demonstrated the conserved yet unpredicted and surprising translational control of bound mRNAs by 4E-T, which does not involve eIF4E (show EIF4E Proteins), nor P-body components.

  5. Data demonstrate that EIF4ENIF1 is associated with dominantly inherited primary ovarian insufficiency.

  6. The c-Jun N-terminal kinase (JNK) is targeted to processing bodies in response to oxidative stress and promotes the phosphorylation of 4E-T.

  7. human P bodies contain the cap-binding protein eIF4E (show EIF4E Proteins) and the related factor eIF4E-transporter (eIF4E (show EIF4E Proteins)-T), suggesting novel roles for these proteins in targeting mRNAs for 5' --> 3' degradation

  8. A role for the eIF4E-binding protein (show NGDN Proteins) 4E-T in P-body formation and mRNA decay is described.

  9. Overexpression of eIF4E (show EIF4E Proteins)-T triggers the movement of eIF4E (show EIF4E Proteins) into the processing bodies.

  10. Hsp90 (show HSP90 Proteins) probably contributes to the correct localization of eIF4E (show EIF4E Proteins) and 4E-T to stress granules and also to the interaction between eIF4E (show EIF4E Proteins) and eIF4G (show EIF4G1 Proteins), both of which may be needed for eIF4E (show EIF4E Proteins) to acquire the physiological functionality

EIF4ENIF1 Protein Profile

Protein Summary

The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic\; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with EIF4ENIF1

  • eukaryotic translation initiation factor 4E nuclear import factor 1 (Eif4enif1)
  • eukaryotic translation initiation factor 4E nuclear import factor 1 (EIF4ENIF1)
  • eukaryotic translation initiation factor 4E nuclear import factor 1 (eif4enif1)
  • 4E-T protein
  • 2610509L04Rik protein
  • A930019J01Rik protein
  • AA410001 protein
  • AU021239 protein
  • Clast4 protein
  • D11Ertd166e protein
  • EIF4ENIF1 protein
  • MGC80355 protein
  • MGC147579 protein
  • RGD1560908 protein
  • wu:fd15a05 protein
  • zgc:101646 protein

Protein level used designations for EIF4ENIF1

eukaryotic translation initiation factor 4E transporter , eukaryotic translation initiation factor 4E nuclear import factor 1 , fd15a05 , eukaryotic translation initiation factor 4E transporter-like , 2610509L04Rik , eIF4E transporter , eIF4E-transporter , 4E-T

GENE ID SPECIES
305468 Rattus norvegicus
416961 Gallus gallus
446545 Xenopus laevis
486366 Canis lupus familiaris
514108 Bos taurus
541411 Danio rerio
738317 Pan troglodytes
780398 Xenopus (Silurana) tropicalis
100137233 Papio anubis
100328731 Oryctolagus cuniculus
100399016 Callithrix jacchus
100477199 Ailuropoda melanoleuca
56478 Homo sapiens
74203 Mus musculus
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