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Eukaryotic Translation Termination Factor 1 Proteins (ETF1)

ETF1 encodes a class-1 polypeptide chain release factor. Additionally we are shipping Eukaryotic Translation Termination Factor 1 Antibodies (23) and Eukaryotic Translation Termination Factor 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ETF1 2107 P62495
ETF1 225363 Q8BWY3
Rat ETF1 ETF1 307503 Q5U2Q7
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Top Eukaryotic Translation Termination Factor 1 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Tetrahymena His tag   1 mg Log in to see 56 to 66 Days
$3,215.67
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$3,219.33
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$3,219.33
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,219.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,219.33
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,223.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,223.00
Details

ETF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Eukaryotic Translation Termination Factor 1 (ETF1) Interaction Partners

Human Eukaryotic Translation Termination Factor 1 (ETF1) interaction partners

  1. New information has been presented on architecture of the eRF1 (show ZFP36L1 Proteins) binding site on mammalian ribosome at various translation termination steps and on conformational rearrangements induced by binding of the release factors.

  2. cryo-electron microscopy (cryo-EM) structures at 3.5-3.8 A resolution of ribosomal complexes containing eRF1 (show ZFP36L1 Proteins) interacting with each of the three stop codons in the A-site

  3. We characterized a region of the eRF1 (show ZFP36L1 Proteins) N-terminal domain, the P1 pocket, that we had previously shown to be involved in termination efficiency. We identified two residues, arginine 65 and lysine 109, as critical for recognition of the three stop codons.

  4. C4 lysyl hydroxylation of eRF1 (show ZFP36L1 Proteins) is required for optimal translational termination

  5. The role of the 41 invariant and conserved N-domain residues in stop codon decoding by human eRF1 (show ZFP36L1 Proteins) was determined.

  6. This work provides mechanistic insight into the coordination between GTP (show AK3 Proteins) hydrolysis by eRF3 and subsequent peptide release by eRF1 (show ZFP36L1 Proteins).

  7. Authors propose that structural variability in the GTS loop may underline the switching between omnipotency and unipotency of eRF1 (show ZFP36L1 Proteins), implying the direct access of the GTS loop to the stop codon.

  8. The NMR data show that the N-domain of human eRF1 (show ZFP36L1 Proteins) exists in two conformational states.

  9. Molecular modeling of eRF1 (show ZFP36L1 Proteins) in the 80S termination complex showed that eRF1 (show ZFP36L1 Proteins) fragments neighboring guanines and adenines of stop signals are compatible with different N domain conformations of eRF1 (show ZFP36L1 Proteins).

  10. By molecular modeling, the eRF1 (show ZFP36L1 Proteins) molecule can be fitted to the A site proximal to the P-site-bound tRNA and to a stop codon in mRNA via a large conformational change to one of its three domains.

Mouse (Murine) Eukaryotic Translation Termination Factor 1 (ETF1) interaction partners

  1. Reverse Transcriptase enhances suppression of termination and that the interaction of RT with eRF1 (show ZFP36L1 Proteins) is required for an appropriate level of translational readthrough.

Eukaryotic Translation Termination Factor 1 (ETF1) Protein Profile

Protein Summary

This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in coding and non-coding transcript variants. Pseudogenes of this gene are found on chromosomes 5, 7 and X.

Gene names and symbols associated with ETF1

  • eukaryotic release factor 1 (eRF1)
  • eukaryotic translation termination factor 1 (etf1)
  • eukaryotic peptide chain release factor subunit 1 (Tb11.22.0012)
  • eukaryotic peptide chain release factor subunit 1 (THAPSDRAFT_22240)
  • eukaryotic peptide chain release factor subunit 1 (TTHERM_00292170)
  • eukaryotic translation termination factor 1 (ETF1)
  • eukaryotic translation termination factor 1 (LOC692937)
  • eukaryotic petide chain release factor subunit 1 (erf1)
  • eukaryotic translation termination factor 1 (Etf1)
  • AI463371 protein
  • CG5605 protein
  • cl1 protein
  • D5S1995 protein
  • D6Ertd109e protein
  • DDBDRAFT_0188023 protein
  • DDBDRAFT_0191343 protein
  • DDB_0188023 protein
  • DDB_0191343 protein
  • Dm0184 protein
  • Dmel\\CG5605 protein
  • ERF protein
  • ERF1 protein
  • group J protein
  • hm:zeh0057 protein
  • l(3)00103 protein
  • l(3)05637 protein
  • l(3)77ABb protein
  • l(3)neo28 protein
  • RF1 protein
  • RRF1 protein
  • SUP45L1 protein
  • TB3-1 protein
  • wu:fa19e07 protein
  • wu:fi31f01 protein
  • zeh0057 protein

Protein level used designations for ETF1

CG5605-PA , CG5605-PB , CG5605-PC , CG5605-PE , CG5605-PF , CG5605-PG , CG5605-PH , CG5605-PI , eRF1-PA , eRF1-PB , eRF1-PC , eRF1-PE , eRF1-PF , eRF1-PG , eRF1-PH , eRF1-PI , eukaryotic peptide chain release factor subunit 1 , etID39694.10 , eRF1 , eukaryotic release factor 1 , eukaryotic translation termination factor 1 , polypeptide chain release factor 1 , protein Cl1 , sup45 (yeast omnipotent suppressor 45) homolog-like 1 , eukaryotic polypeptide chain release factor 1 , SUP1 homolog , omnipotent suppressor protein 1 homolog , suppressor , Eukaryotic release factor 1 , Protein Cl1

GENE ID SPECIES
40240 Drosophila melanogaster
266989 Danio rerio
394632 Xenopus (Silurana) tropicalis
3664379 Trypanosoma brucei brucei strain 927/4 GUTat10.1
7453361 Thalassiosira pseudonana CCMP1335
7839615 Tetrahymena thermophila
416182 Gallus gallus
462098 Pan troglodytes
692937 Bombyx mori
8626719 Dictyostelium discoideum AX4
100020176 Monodelphis domestica
2107 Homo sapiens
225363 Mus musculus
307503 Rattus norvegicus
541077 Bos taurus
100009553 Oryctolagus cuniculus
399462 Xenopus laevis
101838018 Mesocricetus auratus
100174012 Pongo abelii
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