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anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) Antibodies

EWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. Additionally we are shipping EWSR1 Proteins (4) and EWSR1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EWSR1 14030 Q61545
EWSR1 2130 Q01844
EWSR1 289752  
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Top anti-EWSR1 Antibodies at antibodies-online.com

Showing 10 out of 146 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EWSR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-EWSR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate Sample Type: HEK cells transfected with pFLAG EWSR1-ATF1Primary Dilution: 1:1000EWSR1 is supported by BioGPS gene expression data to be expressed in HEK293 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of EWSR1 (arrow) using rabbit polyclonal EWSR1 Antibody (C-term) (ABIN658497). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EWSR1 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of EWSR1 Antibody (C-term) in A2058 cell line lysates (35ug/lane). EWSR1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-EWSR1 Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-EWSR1  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate  EWSR1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- EWSR1 Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Goat Un-conjugated IHC, ELISA, WB EB09167 (0.1µg/ml) staining of nuclear HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details

EWSR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-EWSR1 Antibodies

  1. Human Polyclonal EWSR1 Primary Antibody for IF, WB - ABIN658497 : Lagirand-Cantaloube, Laud, Lilienbaum, Tirode, Delattre, Auclair, Kryszke: EWS-FLI1 inhibits TNFalpha-induced NFkappaB-dependent transcription in Ewing sarcoma cells. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 5 references for ABIN658497

  2. Human Polyclonal EWSR1 Primary Antibody for ELISA, WB - ABIN1451580 : Delattre, Zucman, Plougastel, Desmaze, Melot, Peter, Kovar, Joubert, de Jong, Rouleau: Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. in Nature 1992 (PubMed)
    Show all 2 references for ABIN1451580

  3. Cow (Bovine) Polyclonal EWSR1 Primary Antibody for WB - ABIN2780666 : Brandal, Panagopoulos, Bjerkehagen, Gorunova, Skjeldal, Micci, Heim: Detection of a t(1;22)(q23;q12) translocation leading to an EWSR1-PBX1 fusion gene in a myoepithelioma. in Genes, chromosomes & cancer 2008 (PubMed)

  4. Human Polyclonal EWSR1 Primary Antibody for EIA, WB - ABIN453643 : Bhagirath, Abe, Nojima, Yoshida: Molecular analysis of a t(11;22) translocation junction in a case of Ewing's sarcoma. in Genes, chromosomes & cancer 1995 (PubMed)

  5. Cow (Bovine) Polyclonal EWSR1 Primary Antibody for EIA, IHC (p) - ABIN375098 : Toretsky, Erkizan, Levenson, Abaan, Parvin, Cripe, Rice, Lee, Uren: Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A. in Cancer research 2006 (PubMed)

More Antibodies against EWSR1 Interaction Partners

Mouse (Murine) Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. EWSR1 is involved in the post-transcriptional regulation of Uvrag (show UVRAG Antibodies) via a miRNA-dependent pathway, resulting in the deregulation of autophagy inhibition.

  2. EWS is essential during the early steps of white adipocyte differentiation, at least in part through its regulation of BMP2 (show BMP2 Antibodies) and BMP4 (show BMP4 Antibodies) expression.

  3. EWS has a role in mitochondrial and cellular energy homeostasis that involves controlling PGC-1alpha (show PPARGC1A Antibodies) protein stability

  4. both Etv1 (show ETV1 Antibodies) and Ewsr1 were necessary for Fgf10 (show FGF10 Antibodies) expression and elongation of the limb bud.

  5. EWS is involved in post-transcriptional regulation of Col4a1 (show COL4A1 Antibodies) and CTGF (show CTGF Antibodies) via a Drosha (show DROSHA Antibodies)-miRNA-dependent pathway.

  6. These results demonstrate that EWS is essential for early brown fat lineage determination.

  7. Forced expression of EWS/ATF1 (show AFT1 Antibodies) resulted in the development of EWS/ATF1 (show AFT1 Antibodies)-dependent sarcomas. Lineage-tracing experiments indicated that neural crest-derived cells were subject to EWS/ATF1 (show AFT1 Antibodies)-driven transformation.

  8. these findings suggest that EWS mediates generation of mature let-7g from pre-let-7g.

  9. EWS is likely to play a significant role in maintaining the functional capacity of stem cells.

  10. Findings suggest that EWS/FLI1 (show FLI1 Antibodies) induces apoptosis, at least partially, through the activation of CASP3 (show CASP3 Antibodies).

Zebrafish Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. Mutation of the EWS gene modulates Sox9 (show SOX9 Antibodies) gene expression essential for chondrocyte differentiation.

  2. Ewsr1 maintains mitotic integrity and proneural cell survival in early zebrafish development

  3. Interaction between EWSR1/FLI1 (show FLI1 Antibodies) and EWSR1 in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation.

Human Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. prevalence of the FUS (show FUS Antibodies)-ERG (show ERG Antibodies) gene fusion in a large cohort of pathologically and molecularly well characterized small blue round cell tumors, lacking other known gene rearrangements

  2. FUS (show FUS Antibodies) and EWS target genes involved in pathways at the RNA regulatory level

  3. Identify SP1 (show PSG1 Antibodies) and PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) signaling as modulators of EWS/FLI1 (show FLI1 Antibodies) gene expression in tumor cell lines.

  4. Case Reports: 2 girls with primary renal myoepithelial carcinomas with a novel EWSR1-KLF15 fusion.

  5. 3'-UTR (show UTS2R Antibodies) poly(T/U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer.

  6. study investigated EWSR1 status in ovarian hemangiomas; all cases were negative for EWSR1 rearrangement; 2 cases demonstrated additional intact copies of EWSR1 indicating aneusomy 22 or structural abnormality of chromosome 22 resulting in apparent duplication of the EWSR1 gene region

  7. The paper investigates the presence of EWS/FLI-1 (show FLI1 Antibodies) fusion in clinically diagnosed sarcoma belonging to different non-Ewing connective tissue tumors.

  8. Results show that RNA-binding protein EWS binds and regulates CCDC6 (show CCDC6 Antibodies) expression at RNA and protein levels.

  9. KLF17 (show KLF17 Antibodies) is also a rare gene fusion partner to EWSR1-rearranged myoepithelial tumors.

  10. The impairment of EWS-dependent midzone formation via the recruitment of Aurora B (show AURKB Antibodies) is a potential mechanism of Ewing sarcoma development.

EWSR1 Antigen Profile

Protein Summary

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11\;22)(q24\;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

Gene names and symbols associated with EWSR1

  • Ewing sarcoma breakpoint region 1 (EWSR1) antibody
  • Ewing sarcoma breakpoint region 1 (ewsr1) antibody
  • Ewing sarcoma breakpoint region 1 (Ewsr1) antibody
  • Ewing sarcoma breakpoint region 1a (ewsr1a) antibody
  • EWS RNA-binding protein 1 (EWSR1) antibody
  • EWS RNA-binding protein 1 (Ewsr1) antibody
  • AU018891 antibody
  • bK984G1.4 antibody
  • DKFZp459K1116 antibody
  • Ews antibody
  • Ewsh antibody
  • EWSR1 antibody
  • fc04c01 antibody
  • wu:fc04c01 antibody

Protein level used designations for EWSR1

RNA-binding protein EWS , Ewing sarcoma RNA-binding protein , Ewing sarcoma breakpoint region 1 , Ewing sarcoma homolog , Ewings sarcoma EWS-Fli1 (type 1) oncogene

GENE ID SPECIES
748264 Pan troglodytes
100034010 Equus caballus
100018014 Monodelphis domestica
100173925 Pongo abelii
100550662 Meleagris gallopavo
100557388 Anolis carolinensis
100595788 Nomascus leucogenys
417022 Gallus gallus
609786 Canis lupus familiaris
534073 Bos taurus
14030 Mus musculus
100156911 Sus scrofa
323597 Danio rerio
2130 Homo sapiens
289752 Rattus norvegicus
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