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Ewing Sarcoma Breakpoint Region 1 (EWSR1) ELISA Kits

EWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. Additionally we are shipping EWSR1 Antibodies (120) and EWSR1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EWSR1 14030 Q61545
EWSR1 2130 Q01844
Anti-Rat EWSR1 EWSR1 289752  
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Top EWSR1 ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 6.25 pg/ml 25-1600 pg/mL 96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days

More ELISA Kits for EWSR1 Interaction Partners

Mouse (Murine) Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. EWSR1 is involved in the post-transcriptional regulation of Uvrag via a miRNA-dependent pathway, resulting in the deregulation of autophagy inhibition.

  2. EWS is essential during the early steps of white adipocyte differentiation, at least in part through its regulation of BMP2 (show BMP2 ELISA Kits) and BMP4 (show BMP4 ELISA Kits) expression.

  3. EWS has a role in mitochondrial and cellular energy homeostasis that involves controlling PGC-1alpha (show PPARGC1A ELISA Kits) protein stability

  4. both Etv1 (show ETV1 ELISA Kits) and Ewsr1 were necessary for Fgf10 (show FGF10 ELISA Kits) expression and elongation of the limb bud.

  5. EWS is involved in post-transcriptional regulation of Col4a1 (show COL4A1 ELISA Kits) and CTGF (show CTGF ELISA Kits) via a Drosha (show DROSHA ELISA Kits)-miRNA-dependent pathway.

  6. These results demonstrate that EWS is essential for early brown fat lineage determination.

  7. Forced expression of EWS/ATF1 (show AFT1 ELISA Kits) resulted in the development of EWS/ATF1 (show AFT1 ELISA Kits)-dependent sarcomas. Lineage-tracing experiments indicated that neural crest-derived cells were subject to EWS/ATF1 (show AFT1 ELISA Kits)-driven transformation.

  8. these findings suggest that EWS mediates generation of mature let-7g from pre-let-7g.

  9. EWS is likely to play a significant role in maintaining the functional capacity of stem cells.

  10. Findings suggest that EWS/FLI1 (show FLI1 ELISA Kits) induces apoptosis, at least partially, through the activation of CASP3 (show CASP3 ELISA Kits).

Zebrafish Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. Mutation of the EWS gene modulates Sox9 (show SOX9 ELISA Kits) gene expression essential for chondrocyte differentiation.

  2. Ewsr1 maintains mitotic integrity and proneural cell survival in early zebrafish development

  3. Interaction between EWSR1/FLI1 (show FLI1 ELISA Kits) and EWSR1 in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation.

Human Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. prevalence of the FUS (show FUS ELISA Kits)-ERG (show ERG ELISA Kits) gene fusion in a large cohort of pathologically and molecularly well characterized small blue round cell tumors, lacking other known gene rearrangements

  2. FUS (show FUS ELISA Kits) and EWS target genes involved in pathways at the RNA regulatory level

  3. Identify SP1 (show PSG1 ELISA Kits) and PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling as modulators of EWS/FLI1 (show FLI1 ELISA Kits) gene expression in tumor cell lines.

  4. Case Reports: 2 girls with primary renal myoepithelial carcinomas with a novel EWSR1-KLF15 (show KLF15 ELISA Kits) fusion.

  5. 3'-UTR (show UTS2R ELISA Kits) poly(T/U) repeat of EWSR1 is altered in microsatellite unstable colorectal cancer.

  6. study investigated EWSR1 status in ovarian hemangiomas; all cases were negative for EWSR1 rearrangement; 2 cases demonstrated additional intact copies of EWSR1 indicating aneusomy 22 or structural abnormality of chromosome 22 resulting in apparent duplication of the EWSR1 gene region

  7. The paper investigates the presence of EWS/FLI-1 (show FLI1 ELISA Kits) fusion in clinically diagnosed sarcoma belonging to different non-Ewing connective tissue tumors.

  8. Results show that RNA-binding protein EWS binds and regulates CCDC6 expression at RNA and protein levels.

  9. KLF17 (show KLF17 ELISA Kits) is also a rare gene fusion partner to EWSR1-rearranged myoepithelial tumors.

  10. The impairment of EWS-dependent midzone formation via the recruitment of Aurora B (show AURKB ELISA Kits) is a potential mechanism of Ewing sarcoma development.

EWSR1 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11\;22)(q24\;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

Gene names and symbols associated with EWSR1

  • Ewing sarcoma breakpoint region 1 (EWSR1) antibody
  • Ewing sarcoma breakpoint region 1 (ewsr1) antibody
  • Ewing sarcoma breakpoint region 1 (Ewsr1) antibody
  • Ewing sarcoma breakpoint region 1a (ewsr1a) antibody
  • EWS RNA-binding protein 1 (EWSR1) antibody
  • EWS RNA-binding protein 1 (Ewsr1) antibody
  • AU018891 antibody
  • bK984G1.4 antibody
  • DKFZp459K1116 antibody
  • Ews antibody
  • Ewsh antibody
  • EWSR1 antibody
  • fc04c01 antibody
  • wu:fc04c01 antibody

Protein level used designations for EWSR1

RNA-binding protein EWS , Ewing sarcoma RNA-binding protein , Ewing sarcoma breakpoint region 1 , Ewing sarcoma homolog , Ewings sarcoma EWS-Fli1 (type 1) oncogene

748264 Pan troglodytes
100034010 Equus caballus
100018014 Monodelphis domestica
100173925 Pongo abelii
100550662 Meleagris gallopavo
100557388 Anolis carolinensis
100595788 Nomascus leucogenys
417022 Gallus gallus
609786 Canis lupus familiaris
534073 Bos taurus
14030 Mus musculus
100156911 Sus scrofa
323597 Danio rerio
2130 Homo sapiens
289752 Rattus norvegicus
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