Ewing Sarcoma Breakpoint Region 1 (EWSR1) ELISA Kits

EWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. Additionally we are shipping EWSR1 Antibodies (151) and EWSR1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EWSR1 14030 Q61545
EWSR1 2130 Q01844
Anti-Rat EWSR1 EWSR1 289752  
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Top EWSR1 ELISA Kits at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse
  96 Tests Log in to see 15 to 18 Days
$875.60
Details

More ELISA Kits for EWSR1 Interaction Partners

Mouse (Murine) Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. EWS is normally O-GlcNAc glycosylated in the brain.

  2. glycosylation of EWS protein

  3. EWSR1 is involved in the post-transcriptional regulation of Uvrag via a miRNA-dependent pathway, resulting in the deregulation of autophagy inhibition.

  4. EWS is essential during the early steps of white adipocyte differentiation, at least in part through its regulation of BMP2 (show BMP2 ELISA Kits) and BMP4 (show BMP4 ELISA Kits) expression.

  5. EWS has a role in mitochondrial and cellular energy homeostasis that involves controlling PGC-1alpha (show PPARGC1A ELISA Kits) protein stability

  6. both Etv1 (show ETV1 ELISA Kits) and Ewsr1 were necessary for Fgf10 (show FGF10 ELISA Kits) expression and elongation of the limb bud.

  7. EWS is involved in post-transcriptional regulation of Col4a1 (show COL4A1 ELISA Kits) and CTGF (show CTGF ELISA Kits) via a Drosha (show DROSHA ELISA Kits)-miRNA-dependent pathway.

  8. These results demonstrate that EWS is essential for early brown fat lineage determination.

  9. Forced expression of EWS/ATF1 (show AFT1 ELISA Kits) resulted in the development of EWS/ATF1 (show AFT1 ELISA Kits)-dependent sarcomas. Lineage-tracing experiments indicated that neural crest-derived cells were subject to EWS/ATF1 (show AFT1 ELISA Kits)-driven transformation.

  10. these findings suggest that EWS mediates generation of mature let-7g from pre-let-7g.

Zebrafish Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. Mutation of the EWS gene modulates Sox9 (show SOX9 ELISA Kits) gene expression essential for chondrocyte differentiation.

  2. Ewsr1 maintains mitotic integrity and proneural cell survival in early zebrafish development

  3. Interaction between EWSR1/FLI1 (show FLI1 ELISA Kits) and EWSR1 in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation.

Human Ewing Sarcoma Breakpoint Region 1 (EWSR1) interaction partners

  1. Aggregation of FET proteins FUS, EWSR1, and TAF15 mediate a pathological change in amyotrophic lateral sclerosis. (Review)

  2. A subgroup of MAML2 fusion-negative mucoepidermoid carcinomas are actually clear cell carcinoma of the salivary gland with EWSR1 translocation.

  3. Study found consistent DNA hypomethylation at enhancers regulated by the disease-defining EWS-FLI1 (show FLI1 ELISA Kits) fusion protein, thus establishing epigenomic enhancer reprogramming as a ubiquitous and characteristic feature of Ewing sarcoma.

  4. Report a distinct group of myxoid mesenchymal neoplasms occurring in children or young adults with a predilection for intracranial locations with EWSR1-AFT1/CREB1 (show CREB1 ELISA Kits)/CREM (show CREM ELISA Kits) fusions.

  5. We conclude that in the context of 22q11-12 regional alterations present in SMARCB1 (show SMARCB1 ELISA Kits)-deleted tumors, simultaneous EWSR1 involvement may be misinterpreted as equivalent to EWSR1 rearrangement. A detailed clinicopathologic correlation and supplementing the EWSR1 FISH assay with complementary methodology is mandatory for correct diagnosis

  6. While our study confirmed that fluorescence in-situ hybridization is a sensitive and specific tool in the diagnosis of EWSR1-associated tumours, atypical fluorescence in-situ hybridization signals and classical rearrangement in entities other than EWSR1-associated tumours can occur

  7. EWSR1 regulates the acetylation of microtubules in a cell cycle-dependent manner through its dynamic location on spindle MTs (show TIMM8A ELISA Kits), and may be a novel regulator for mitosis progress independent of its translocation.

  8. Studies provide evidence that FUS/TLS (show FUS ELISA Kits), EWS and TAF15 proteins play a major role in neurodegenerative disorders. (review).

  9. We identified EWSR1 rearrangement in 25% of Ectomesenchymal chondromyxoid tumour

  10. EWSR1-related rearrangement was detected extraskeletal myxoid chondrosarcoma

EWSR1 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11\;22)(q24\;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

Gene names and symbols associated with EWSR1

  • Ewing sarcoma breakpoint region 1 (EWSR1) antibody
  • Ewing sarcoma breakpoint region 1 (ewsr1) antibody
  • Ewing sarcoma breakpoint region 1 (Ewsr1) antibody
  • Ewing sarcoma breakpoint region 1a (ewsr1a) antibody
  • EWS RNA-binding protein 1 (EWSR1) antibody
  • EWS RNA-binding protein 1 (Ewsr1) antibody
  • AU018891 antibody
  • bK984G1.4 antibody
  • DKFZp459K1116 antibody
  • Ews antibody
  • Ewsh antibody
  • EWSR1 antibody
  • fc04c01 antibody
  • wu:fc04c01 antibody

Protein level used designations for EWSR1

RNA-binding protein EWS , Ewing sarcoma RNA-binding protein , Ewing sarcoma breakpoint region 1 , Ewing sarcoma homolog , Ewings sarcoma EWS-Fli1 (type 1) oncogene

GENE ID SPECIES
748264 Pan troglodytes
100034010 Equus caballus
100018014 Monodelphis domestica
100173925 Pongo abelii
100550662 Meleagris gallopavo
100557388 Anolis carolinensis
100595788 Nomascus leucogenys
417022 Gallus gallus
609786 Canis lupus familiaris
534073 Bos taurus
14030 Mus musculus
100156911 Sus scrofa
323597 Danio rerio
2130 Homo sapiens
289752 Rattus norvegicus
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