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anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 1 (ERCC1) Antibodies

The product of ERCC1 functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse ERCC1 ERCC1 13870 P07903
ERCC1    
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Top anti-ERCC1 Antibodies at antibodies-online.com

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Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 5 to 6 Days
$485.80
Details

ERCC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


More Antibodies against ERCC1 Interaction Partners

Mouse (Murine) Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 1 (ERCC1) interaction partners

  1. these results establish USP45 as a new regulator of XPF (show ERCC4 Antibodies)-ERCC1 crucial for efficient DNA repair

  2. ERCC1 is critical for protecting chondrocytes from catabolic stress and is associated with the pathophysiology of osteoarthritis.

  3. SLX4 (show BTBD12 Antibodies) is a tumor suppressor, which activates XPF (show ERCC4 Antibodies)-ERCC1 nuclease (show DCLRE1C Antibodies) specificity in DNA crosslink repair.

  4. ERCC1 is essential for melanoma growth and resistance to cisplatin.

  5. Smad4 (show SMAD4 Antibodies) loss-associated Snail (show SNAI1 Antibodies) reduction compromises Ercc1-mediated DNA repair, contributing to increased UV-induced skin carcinogenesis.

  6. analysis of accelerated loss of hearing and vision in the DNA-repair deficient Ercc1(delta/-) mouse

  7. This study demonistrated that the ERCC1 deficiency-associated downregulation of the cholesterol biosynthesis pathway is at least in part due to lowered expression of its master transcription factor SREBF2 (show SREBF2 Antibodies)

  8. we have identified a novel skin-specific Ercc1 transcript in mice that originates from a promoter approximately 400 bp upstream of the normal promoter, rather than from more distant potential transcriptional start sites.

  9. Ercc1(Delta/-) mice develop widespread astrocytosis and microgliosis, and motor neuron loss and denervation of skeletal muscle fibers.

  10. Performed metabolic profiling of serum and urine of the ERCC1(d/-) mouse, which has a modified ERCC1 gene, in comparison to wild type ERCC1 mice and in relation to aging by (1)H NMR spectroscopy.

ERCC1 Antigen Profile

Protein Summary

The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.

Gene names and symbols associated with ERCC1

  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (Ercc1) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ercc1) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ERCC1) antibody
  • DNA excision repair protein ERCC-1 (CC1G_04546) antibody
  • DNA excision repair protein ERCC-1 (CpipJ_CPIJ013903) antibody
  • DNA excision repair protein ERCC-1 (PITG_13719) antibody
  • DNA excision repair protein ERCC-1 (ercc1) antibody
  • Ercc-1 antibody
  • ercc1 antibody

Protein level used designations for ERCC1

DNA excision repair protein ERCC-1 , excision repair 1 , excision repair cross-complementing 1 , excision repair protein , excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)

GENE ID SPECIES
13870 Mus musculus
380190 Xenopus laevis
450179 Pan troglodytes
574267 Macaca mulatta
6006551 Coprinopsis cinerea okayama7130
6048458 Culex quinquefasciatus
9461287 Phytophthora infestans T30-4
100135224 Xenopus (Silurana) tropicalis
100286713 Salmo salar
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