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DNA helicase that acts as an essential component of the spindle assembly checkpoint. Additionally we are shipping Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like Proteins (3) and many more products for this protein.
Showing 10 out of 47 products:
Human Polyclonal ERCC6L Primary Antibody for WB - ABIN527207
Laulier, Cheng, Stark: The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation. in Nucleic acids research 2011
Show all 4 references for ABIN527207
Human Monoclonal ERCC6L Primary Antibody for ELISA, WB - ABIN565778
Leng, Bessuso, Jung, Wang, Qin: Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase. in Cell cycle (Georgetown, Tex.) 2008
Show all 2 references for ABIN565778
PICH and Topo II (show TOP2 Antibodies) cooperate to prevent chromosome missegregation events in mitosis.
PICH is a SUMO-interacting protein and a mitotic SUMO substrate.
PICH binds to BLM and enables BLM localization to anaphase centromeric threads. PICH and BLM unravel centromeric chromatin and keep anaphase DNA threads mostly free of nucleosomes.
the PICH-Plk1 (show PLK1 Antibodies) complex plays a critical role in maintaining prometaphase chromosome architecture
the spindle checkpoint failure formerly attributed to the depletion of PICH most likely reflects an off-target effect that causes the lowering of Mad2 (show MAD2L1 Antibodies) transcript and protein.
PICH phosphorylation and its ATPase (show DNAH8 Antibodies) activity are required for mitotic chromosome compaction through the targeting of Plk1 (show PLK1 Antibodies) to chromosome arms.
Functional characterization of the mouse Ercc6l ortholog.
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
DNA excision repair protein ERCC-6-like
, excision repair cross-complementing rodent repair deficiency, complementation group 6-like
, excision repair cross-complementing rodent repair deficiency, complementation group 6
, excision repair cross-complementing rodent repair deficiency complementation group 6-like
, ATP-dependent helicase ERCC6-like
, SNF2/RAD54 family protein
, excision repair cross-complementing rodent repair deficiency complementation group 6 - like
, Plk1-interacting checkpoint helicase
, excision repair protein ERCC6-like
, tumor antigen BJ-HCC-15