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Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like Proteins (ERCC6L)

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Additionally we are shipping Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like Antibodies (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ERCC6L ERCC6L 317252  
ERCC6L 236930 Q8BHK9
ERCC6L 54821 Q2NKX8
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Top Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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ERCC6L Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) Interaction Partners

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) interaction partners

  1. PICH and Topo II (show TOP2 Proteins) cooperate to prevent chromosome missegregation events in mitosis.

  2. PICH is a SUMO-interacting protein and a mitotic SUMO substrate.

  3. PICH binds to BLM and enables BLM localization to anaphase centromeric threads. PICH and BLM unravel centromeric chromatin and keep anaphase DNA threads mostly free of nucleosomes.

  4. the PICH-Plk1 complex plays a critical role in maintaining prometaphase chromosome architecture

  5. the spindle checkpoint failure formerly attributed to the depletion of PICH most likely reflects an off-target effect that causes the lowering of Mad2 (show MAD2L1 Proteins) transcript and protein.

  6. PICH phosphorylation and its ATPase activity are required for mitotic chromosome compaction through the targeting of Plk1 to chromosome arms.

  7. Functional characterization of the mouse Ercc6l ortholog.

Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L) Protein Profile

Protein Summary

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Gene names and symbols associated with ERCC6L

  • excision repair cross-complementing rodent repair deficiency, complementation group 6-like (ERCC6L)
  • DNA excision repair protein ERCC-6-like (LOC100020004)
  • DNA excision repair protein ERCC-6-like (LOC100373376)
  • DNA excision repair protein ERCC-6-like (LOC100442808)
  • excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6)
  • DNA excision repair protein ERCC-6-like (LOC100494766)
  • DNA excision repair protein ERCC-6-like (LOC100552957)
  • DNA excision repair protein ERCC-6-like (LOC100560751)
  • DNA excision repair protein ERCC-6-like (LOC100563247)
  • DNA excision repair protein ERCC-6-like (LOC100622071)
  • DNA excision repair protein ERCC-6-like (LOC100643440)
  • excision repair cross-complementing rodent repair deficiency complementation group 6 - like (Ercc6l)
  • excision repair cross-complementing rodent repair deficiency complementation group 6 like (Ercc6l)
  • excision repair cross-complementing rodent repair deficiency, complementation group 6-like (ercc6l)
  • BC004701 protein
  • D330021P09Rik protein
  • fc22h03 protein
  • PICH protein
  • RAD26L protein
  • RGD1565734 protein
  • si:ch211-278b8.3 protein
  • wu:fc22h03 protein

Protein level used designations for ERCC6L

DNA excision repair protein ERCC-6-like , excision repair cross-complementing rodent repair deficiency, complementation group 6-like , excision repair cross-complementing rodent repair deficiency, complementation group 6 , excision repair cross-complementing rodent repair deficiency complementation group 6-like , ATP-dependent helicase ERCC6-like , SNF2/RAD54 family protein , excision repair cross-complementing rodent repair deficiency complementation group 6 - like , Plk1-interacting checkpoint helicase , excision repair protein ERCC6-like , tumor antigen BJ-HCC-15

GENE ID SPECIES
100052221 Equus caballus
100020004 Monodelphis domestica
100373376 Saccoglossus kowalevskii
100432874 Pongo abelii
100442808 Pongo abelii
100473730 Ailuropoda melanoleuca
100479265 Ailuropoda melanoleuca
100494766 Xenopus (Silurana) tropicalis
100552957 Anolis carolinensis
100560751 Anolis carolinensis
100563247 Anolis carolinensis
100584141 Nomascus leucogenys
100622071 Sus scrofa
100643440 Bombus terrestris
317252 Rattus norvegicus
236930 Mus musculus
54821 Homo sapiens
782916 Bos taurus
100005291 Danio rerio
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