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anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like 2 (ERCC6L2) Antibodies

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Additionally we are shipping ERCC6L2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ERCC6L2 76251 Q6DI94,Q9JIM3
ERCC6L2 54821 Q2NKX8
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Top anti-ERCC6L2 Antibodies at antibodies-online.com

Showing 9 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of RAD26L Antibody (Center) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the RAD26 antibody detected the RAD26 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of Hela cells using RAD26L Antibody (N-term) Cat.-No AP53561PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of RAD26L Antibody (N-term) in Hela cell line lysates (35ug/lane). This demonstrates the RAD26 antibody detected the RAD26 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB Western Blot showing 9330134C04Rik antibody used at a concentration of 1.0 ug/ml against Mouse Liver Lysate 50 μg Log in to see 7 to 9 Days
$473.93
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details

ERCC6L2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human


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Top referenced anti-ERCC6L2 Antibodies

  1. Human Polyclonal ERCC6L2 Primary Antibody for EIA, WB - ABIN954432 : Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007 (PubMed)
    Show all 2 references for ABIN954432

  2. Human Polyclonal ERCC6L2 Primary Antibody for EIA, FACS - ABIN954433 : Venter, Adams, Myers, Li, Mural, Sutton, Smith, Yandell, Evans, Holt, Gocayne, Amanatides, Ballew, Huson, Wortman, Zhang, Kodira, Zheng, Chen, Skupski, Subramanian, Thomas, Zhang, Gabor Miklos et al.: The sequence of the human genome. ... in Science (New York, N.Y.) 2001 (PubMed)
    Show all 2 references for ABIN954433

More Antibodies against ERCC6L2 Interaction Partners

Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like 2 (ERCC6L2) interaction partners

  1. PICH and Topo II (show TOP2 Antibodies) cooperate to prevent chromosome missegregation events in mitosis.

  2. PICH is a SUMO-interacting protein and a mitotic SUMO substrate.

  3. These observations identify a distinct bone-marrow-failure syndrome due to mutations in ERCC6L2, a gene implicated in DNA repair and mitochondrial function.

  4. PICH binds to BLM and enables BLM localization to anaphase centromeric threads. PICH and BLM unravel centromeric chromatin and keep anaphase DNA threads mostly free of nucleosomes.

  5. the PICH-Plk1 (show PLK1 Antibodies) complex plays a critical role in maintaining prometaphase chromosome architecture

  6. the spindle checkpoint failure formerly attributed to the depletion of PICH most likely reflects an off-target effect that causes the lowering of Mad2 (show MAD2L1 Antibodies) transcript and protein.

  7. PICH phosphorylation and its ATPase (show DNAH8 Antibodies) activity are required for mitotic chromosome compaction through the targeting of Plk1 (show PLK1 Antibodies) to chromosome arms.

  8. Functional characterization of the mouse Ercc6l (show ERCC6L Antibodies) ortholog.

ERCC6L2 Antigen Profile

Protein Summary

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Gene names and symbols associated with ERCC6L2

  • excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2 (Ercc6l2) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 6-like (ERCC6L) antibody
  • excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2 (ERCC6L2) antibody
  • 0610007P08Rik antibody
  • 1700019D06Rik antibody
  • 9330134C04Rik antibody
  • C9orf102 antibody
  • PICH antibody
  • RAD26L antibody
  • SR278 antibody

Protein level used designations for ERCC6L2

RAD26L hypothetical protein , putative repair and recombination helicase RAD26L , stretch responsive protein 278 , ATP-dependent helicase ERCC6-like , DNA excision repair protein ERCC-6-like , Plk1-interacting checkpoint helicase , SNF2/RAD54 family protein , excision repair cross-complementing rodent repair deficiency complementation group 6 - like , excision repair protein ERCC6-like , tumor antigen BJ-HCC-15 , putative DNA repair and recombination protein RAD26-like

GENE ID SPECIES
76251 Mus musculus
54821 Homo sapiens
375748 Homo sapiens
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