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Exocyst Complex Component 2 (EXOC2) ELISA Kits

The protein encoded by EXOC2 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Additionally we are shipping Exocyst Complex Component 2 Antibodies (31) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human EXOC2 EXOC2 55770 Q96KP1
Anti-Mouse EXOC2 EXOC2 66482 Q9D4H1
Anti-Rat EXOC2 EXOC2 171455 O54921
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More ELISA Kits for Exocyst Complex Component 2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Exocyst Complex Component 2 (EXOC2) interaction partners

  1. Sec5 concentrates at the sub-apical complex, indicating a role for Sec5 in the polarized epithelium.

  2. Germline clones of sec5 possess defects in membrane addition and the posterior positioning of the oocyte.

  3. Sec5, Sec6 (show EXOC3 ELISA Kits) and Sec8 (show EXOC4 ELISA Kits) act as a complex, each member dependent on the others for proper localization and function

  4. Rab11 forms a complex with Sec5. Sec5 interacts with Sec6 suggesting the exocyst is a Rab11 effector that facilitates protein transport to the apical rhabdomere in Drosophila photoreceptors

  5. The Drosophila exocyst component sec5 in epithelial cells results in DE-Cad (show CAD ELISA Kits) accumulation in an enlarged Rab11 (show RAB11A ELISA Kits) recycling endosomal compartment and inhibits DE-Cad (show CAD ELISA Kits) delivery to the membrane.

Human Exocyst Complex Component 2 (EXOC2) interaction partners

  1. data suggest that the induction of SGK1 (show SGK1 ELISA Kits) through treatment with dexamethasone alters MT dynamics to increase Sec5-GEF-H1 (show ARHGEF2 ELISA Kits) interactions, which promote GEF-H1 (show ARHGEF2 ELISA Kits) targeting to adhesion sites.

  2. Exocyst sec5 regulates exocytosis of newcomer insulin (show INS ELISA Kits) granules underlying biphasic insulin (show INS ELISA Kits) secretion.

  3. We identified interactions between RalA (show rala ELISA Kits) and its effectors sec5 and exo84 (show EXO84 ELISA Kits) in the Exocyst complex as directly necessary for migration and invasion of prostate cancer tumor cells.

  4. Data show that Mc1R (show MSHR ELISA Kits), HERC2 (show HERC2 ELISA Kits), IRF4 (show IRF4 ELISA Kits), TYR (show TYR ELISA Kits) and EXOC2 are ranked highest in hair color prediction analysis.

  5. shRNA-mediated knockdown of the Ral effector proteins Sec5 and Exo84, but less so in the case of RalBP1, reduced oncogenic RalGEF-mediated transformation and oncogenic Ras-driven tumorigenic growth of human cells.

  6. SEC5 has been identified as a binding partner of deafness locus putative guanine nucleotide exchange factor (show RASGRF1 ELISA Kits).

  7. evidence that mammalian exocyst components are present as distinct subcomplexes on vesicles and the plasma membrane and that Ral (show rala ELISA Kits) GTPases regulate the assembly interface of a full octameric exocyst complex through interaction with Sec5 and Exo84 (show EXO84 ELISA Kits)

  8. These observations define the mechanistic contribution of RalGTPases to cancer cell survival and reveal the RalB (show Ralb ELISA Kits)/Sec5 effector complex as a component of TBK1 (show TBK1 ELISA Kits)-dependent innate immune signaling.

  9. Localization of Exocyst and, by extension, targeting of Exocyst-dependent cargo, is dependent on Ral (show rala ELISA Kits) GTPases, which control association between Sec5 and paxillin (show PXN ELISA Kits).

Mouse (Murine) Exocyst Complex Component 2 (EXOC2) interaction partners

  1. Exocyst sec5 regulates exocytosis of newcomer insulin (show INS ELISA Kits) granules underlying biphasic insulin (show INS ELISA Kits) secretion.

  2. the structure of the Ral (show rala ELISA Kits)-binding domain of Sec5

Arabidopsis thaliana Exocyst Complex Component 2 (EXOC2) interaction partners

  1. SEC5a copurifies in a high molecular mass fraction of 900 kD, and functions as a subunit in a exocyst complex that plays important roles in morphogenesis.

Exocyst Complex Component 2 (EXOC2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with EXOC2

  • CG8843 gene product from transcript CG8843-RA (sec5) antibody
  • exocyst complex component 2 (EXOC2) antibody
  • exocyst complex component 2 (LOC100226726) antibody
  • exocyst complex component 2 (Exoc2) antibody
  • exocyst complex component sec5 (SEC5A) antibody
  • Protein SEC-5 (sec-5) antibody
  • 2410030I24Rik antibody
  • AI648199 antibody
  • CG8843 antibody
  • Dmel\\CG8843 antibody
  • dsec5 antibody
  • exocyst complex component sec5 antibody
  • F7O12.2 antibody
  • F7O12_2 antibody
  • Rsec5 antibody
  • Sec-5 antibody
  • SEC5 antibody
  • Sec5l1 antibody
  • Sec5p antibody

Protein level used designations for EXOC2

CG8843-PA , sec5-PA , exocyst complex component 2 , SEC5-like 1 , exocyst complex component Sec5 , SEC5 homolog

GENE ID SPECIES
33563 Drosophila melanogaster
420889 Gallus gallus
100226726 Taeniopygia guttata
55770 Homo sapiens
66482 Mus musculus
171455 Rattus norvegicus
844020 Arabidopsis thaliana
174459 Caenorhabditis elegans
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