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anti-Exocyst Complex Component 4 (EXOC4) Antibodies

The protein encoded by EXOC4 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Additionally we are shipping Exocyst Complex Component 4 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EXOC4 60412 Q96A65
EXOC4 20336 O35382
EXOC4 116654 Q62824
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Top anti-Exocyst Complex Component 4 Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-EXOC4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Sec8 on a MDCK cell lysate (Canine kidney, ATCC CCL-34). Lane 1: 1:1000, lane 2: 1: 2000, lane 3: 1: 4000 dilution of the mouse anti-Sec8 antibody. Immunofluorescence of AN3 CA cells (Human endometrial adenocarcinoma, ATCC HTB-111). 50 μg Log in to see 5 to 6 Days
$207.71
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-EXOC4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta WB Suggested Anti-EXOC4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB EXOC4 monoclonal antibody (M06), clone 4F1 Western Blot analysis of EXOC4 expression in Hela S3 NE . Detection limit for recombinant GST tagged EXOC4 is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated WB EXOC4 monoclonal antibody (M06), clone 4F1 Western Blot analysis of EXOC4 expression in Hela NE. Detection limit for recombinant GST tagged EXOC4 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Mouse Un-conjugated IHC (p), IP, WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with EXOC4 antibody ABIN364381 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated WB EXOC4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Mouse Rabbit Un-conjugated IHC, WB   100 μL Log in to see 7 to 8 Days
$454.67
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.1 KDa) . 50 μL Log in to see 9 Days
$298.57
Details

EXOC4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Exocyst Complex Component 4 Antibodies

  1. Mouse (Murine) Polyclonal EXOC4 Primary Antibody for IHC, WB - ABIN350317 : Beausoleil, Villén, Gerber, Rush, Gygi: A probability-based approach for high-throughput protein phosphorylation analysis and site localization. in Nature biotechnology 2006 (PubMed)
    Show all 5 references for ABIN350317

  2. Chicken Monoclonal EXOC4 Primary Antibody for IF, IP - ABIN968092 : Charron, Nakamura, Bacallao, Wandinger-Ness: Compromised cytoarchitecture and polarized trafficking in autosomal dominant polycystic kidney disease cells. in The Journal of cell biology 2000 (PubMed)
    Show all 4 references for ABIN968092

  3. Human Monoclonal EXOC4 Primary Antibody for ELISA, WB - ABIN528409 : Imai, Yoshie, Haga-Tsujimura, Nashida, Shimomura: Exocyst subunits are involved in isoproterenol-induced amylase release from rat parotid acinar cells. in European journal of oral sciences 2012 (PubMed)

  4. Chicken Polyclonal EXOC4 Primary Antibody for WB - ABIN2786600 : Pohl, Jentsch: Final stages of cytokinesis and midbody ring formation are controlled by BRUCE. in Cell 2008 (PubMed)

More Antibodies against Exocyst Complex Component 4 Interaction Partners

Fruit Fly (Drosophila melanogaster) Exocyst Complex Component 4 (EXOC4) interaction partners

  1. Sec5 (show EXOC2 Antibodies), Sec6 (show EXOC3 Antibodies) and Sec8 act as a complex, each member dependent on the others for proper localization and function

  2. No evidence that Sec8 is required for basal neurotransmission, though glutamate (show GRIN2A Antibodies) receptor trafficking was mildly disrupted in sec8 mutants.

Human Exocyst Complex Component 4 (EXOC4) interaction partners

  1. Sec8 regulates histone-modifying proteins ATF2 (show ATF2 Antibodies) and RNF20 (show RNF20 Antibodies).

  2. Sec8 knockdown in HSC3 cells resulted in reduced expressions of PAK1 (show PAK1 Antibodies) and PAK2 (show PAK2 Antibodies) by upregulating Pirh2 (show RCHY1 Antibodies) and Siah1 (show SIAH1 Antibodies) expression, which inhibited the ERK (show EPHB2 Antibodies) or p38 MAPK (show MAPK14 Antibodies) signalling pathway and cytokeratin8 phosphorylation and cell migration.

  3. knockdown of Sec8 enhances the binding of JIP4 (show SPAG9 Antibodies) to MAPK (show MAPK1 Antibodies) kinase 4, thereby decreasing the phosphorylation of MAPK (show MAPK1 Antibodies) kinase 4, JNK (show MAPK8 Antibodies), and p38 (show CRK Antibodies).

  4. Exome sequencing revealed a likely pathogenic mutation in three novel candidate MKS (show MKS1 Antibodies) disease genes-C5orf42 (show C5ORF42 Antibodies), EVC2 (show EVC2 Antibodies) and SEC8 (also known as EXOC4), which encodes an exocyst protein with an established role in ciliogenesis

  5. High Sec8 expression is associated with progression of oral squamous-cell carcinoma by secretion of matrix metalloproteinases.

  6. EXOC4 is involved in insulin (show INS Antibodies)-stimulated glucose transport and may be a candidate for an association with type 2 diabetes.

  7. The exocyst subunits Sec3 (show EXOC1 Antibodies) and Sec8 interact with the polarity protein IQGAP1 (show IQGAP1 Antibodies) and that this interaction is triggered by active Cdc42 (show CDC42 Antibodies) and RhoA (show RHOA Antibodies), which are essential for matrix degradation.

Mouse (Murine) Exocyst Complex Component 4 (EXOC4) interaction partners

  1. SAP102 (show DLG3 Antibodies) interacts with the PDZ (show INADL Antibodies)-binding domain of Sec8, a member of the exocyst complex. Interactions between the two proteins are involved in the delivery of N-methyl-D-aspartate receptors to the cell surface in heterologous cells and neurons.

  2. the exocyst complex serves to selectively regulate the docking of insulin (show INS Antibodies)-containing vesicles at sites of release close to the plasma membrane

  3. Sec8 controls the directional movement of AMPA (show GRIA3 Antibodies) receptors towards synapses through PDZ (show INADL Antibodies)-dependent interactions.

  4. Insulin (show INS Antibodies) stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes.

  5. Interaction of Discs large 1 (Dlg1 (show DLG4 Antibodies)) with the Sec8 exocyst component promotes membrane addition, whereas with myotubularin-related protein 2 (Mtmr2 (show MTMR2 Antibodies)), negatively regulates membrane formation.

Arabidopsis thaliana Exocyst Complex Component 4 (EXOC4) interaction partners

  1. The amount of pectinaceous mucilage and seed coat structure in sec8 and exo70A1 exocyst mutants, was characterized.

  2. An allelic series of six independent T-DNA mutations reveal a role for SEC8 in male gametophyte function.

  3. SEC8 copurifies in a high molecular mass fraction of 900 kD, interacts with SEC6 (show EXOC3 Antibodies), and functions as a subunit in a exocyst complex that plays important roles in morphogenesis.

Exocyst Complex Component 4 (EXOC4) Antigen Profile

Protein Summary

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with EXOC4

  • CG2095 gene product from transcript CG2095-RA (sec8) antibody
  • exocyst complex component 4 (EXOC4) antibody
  • exocyst complex component 4 (CpipJ_CPIJ001354) antibody
  • exocyst complex component 4 (Exoc4) antibody
  • exocyst complex component 4 (exoc4) antibody
  • Protein SEC-8 (sec-8) antibody
  • subunit of exocyst complex 8 (SEC8) antibody
  • ALR antibody
  • ATSEC8 antibody
  • C78892 antibody
  • CG2095 antibody
  • DKFZp459N1430 antibody
  • Dmel\\CG2095 antibody
  • dsec8 antibody
  • fun antibody
  • SEC8 antibody
  • Sec8l1 antibody
  • Sec8p antibody
  • si:ch211-92l17.2 antibody
  • si:rp71-18a24.2 antibody
  • subunit of exocyst complex 8 antibody

Protein level used designations for EXOC4

CG2095-PA , funnel cakes , sec8-PA , SEC8 protein , exocyst complex component 4 , SEC8-like 1 , exocyst complex component Sec8 , augmenter of liver regeneration (ALR) pseudogene , rSec8 , secretory protein SEC8

GENE ID SPECIES
40712 Drosophila melanogaster
463740 Pan troglodytes
482250 Canis lupus familiaris
6032553 Culex quinquefasciatus
100065209 Equus caballus
100171903 Pongo abelii
100583695 Nomascus leucogenys
60412 Homo sapiens
20336 Mus musculus
116654 Rattus norvegicus
559866 Danio rerio
779032 Xenopus laevis
416700 Gallus gallus
537690 Bos taurus
172924 Caenorhabditis elegans
820201 Arabidopsis thaliana
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