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In yeast and rat, Sec15 is part of a multiprotein complex that is required for targeted exocytosis.[supplied by OMIM, Apr 2004].. Additionally we are shipping EXOC6B Proteins (3) and many more products for this protein.
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EXOC6B and the exocyst complex might play an important role in the molecular pathogenesis of intellectual disability.
We report a 2p13.2 microdeletion in 2 subjects encompasing 2 genes, EXOC6B and CYP26B12 with clinical effects on cognitive function, and craniofacial and skeletal development.
Data suggest that the Rabin8 (show RAB3IP Antibodies)-Rab8 (show RAB8A Antibodies)-Sec15 (show EXOC6 Antibodies) interaction may couple the activation of Rab8 (show RAB8A Antibodies) to the recruitment of the Rab8 (show RAB8A Antibodies) effector and is involved in the regulation of vesicular trafficking for primary cilium formation.
TNS3 (show TNS3 Antibodies)-EXOC6B and EXOC6B-TNS3 (show TNS3 Antibodies) fusion transcripts are detected in a premature male newborn with a complex multisystemic phenotype associated with a balanced translocation.
In yeast and rat, Sec15 is part of a multiprotein complex that is required for targeted exocytosis.
exocyst complex component 6B
, SEC15-like 2
, SEC15-like 2-like
, SEC15 homolog B
, SEC15-like protein 2
, exocyst complex component Sec15B