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anti-Exoribonuclease 1 (ERI1) Antibodies

RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Additionally we are shipping ERI1 Proteins (6) and ERI1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ERI1 90459 Q8IV48
ERI1 67276 Q7TMF2
ERI1 361159 Q5FVR4
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Top anti-ERI1 Antibodies at antibodies-online.com

Showing 10 out of 59 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-THEX1 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-THEX1 Antibody Titration: 2.5ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate WB Suggested Anti-THEX1  Antibody Titration: 2.5 µg/mL ELISA Titer: 1:1562500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ERI1 / THEX1 (N-term) Antibody (N-term) in 293 cell line lysates (35ug/lane). This demonstrates the ERI1 antibody detected the ERI1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB ERI1 Antibody (N-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ERI1 antibody detected the ERI1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ERI1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ERI1. Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ERI1 mouse monoclonal antibody. (ABIN2455443) 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details

ERI1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)


Rat (Rattus)
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Top referenced anti-ERI1 Antibodies

  1. Human Polyclonal ERI1 Primary Antibody for WB - ABIN2801967 : Dominski, Yang, Kaygun, Dadlez, Marzluff: A 3' exonuclease that specifically interacts with the 3' end of histone mRNA. in Molecular cell 2003 (PubMed)
    Show all 5 references for ABIN2801967

  2. Human Polyclonal ERI1 Primary Antibody for EIA, WB - ABIN952107 : Cheng, Patel: Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP. in Journal of molecular biology 2004 (PubMed)
    Show all 2 references for ABIN952107

  3. Chicken Polyclonal ERI1 Primary Antibody for WB - ABIN2776656 : Kupsco, Wu, Marzluff, Thapar, Duronio: Genetic and biochemical characterization of Drosophila Snipper: A promiscuous member of the metazoan 3'hExo/ERI-1 family of 3' to 5' exonucleases. in RNA (New York, N.Y.) 2006 (PubMed)

More Antibodies against ERI1 Interaction Partners

Human Exoribonuclease 1 (ERI1) interaction partners

  1. the crystal structure of a ternary complex of human SLBP (show SLBP Antibodies) RNA binding domain, human 3'hExo, and a 26-nucleotide stem-loop RNA is reported.

  2. 3'hExo is a primary candidate for the exonuclease (show EXO1 Antibodies) that initiates rapid decay of histone mRNA upon completion and/or inhibition of DNA replication

  3. molecular cloning; degrades siRNAs in vitro[ERI-1]

  4. Data describe the structure of the nuclease (show DCLRE1C Antibodies) domain of 3'-5'-exoribonuclease (3'hExo) complexed with rAMP in the presence of magnesium at 1.6 A resolution.

  5. 3'hExo is a 3' exonuclease (show EXO1 Antibodies) specifically interacting with the 3' end of histone mRNA

Mouse (Murine) Exoribonuclease 1 (ERI1) interaction partners

  1. data demonstrate how degradation of histone mRNAs is initiated when 3' oligouridylation creates a cis (show CISH Antibodies) element that enables Eri1 to process the double-stranded stem-loop structure

  2. Mouse Eri1 regulates miRNA homeostasis in lymphocytes and is required for normal NK-cell development and antiviral immunity.

  3. The roles of meri-1 (mouse enhanced RNAi) and adar1 (show ADAR Antibodies) in the regulation of RNA interference are reported.

  4. Findings indicate that Eri1 catalyzes the final trimming step in 5.8S rRNA processing, functionally and spatially connecting this regulator of RNAi with the basal translation machinery.

Caenorhabditis elegans (C. elegans) Exoribonuclease 1 (ERI1) interaction partners

  1. results identify novel components of the endo RNAi machinery, demonstrate differential requirements for the Eri factors in the sperm-producing germline, and begin to delineate the functional requirement for the ERI/DICER (show DICER1 Antibodies) complex in sperm development

  2. After exposure to dsRNA or siRNAs, animals with eri-1 mutations accumulate more siRNAs than wild-type animals; a negative regulator that may normally function to limit the duration, cell-type specificity or endogenous functions of RNA interference

  3. Feeding unc-13 & eri-1 strains dsRNA corresponding to a neuronally expressed GFP reporter resulted in reduction of GFP in double mutants compared to GFP expression in eri-1 mutants, indicating that UNC-13 functions in conjunction with ERI-1 in RNAi.

  4. These results provide additional support for the hypothesis that RRF (show MRRF Antibodies)-3 and ERI-1 act together in the endo-siRNA pathway, and furthermore suggests their involvement in additional biological processes.

  5. In C. elegans, two protein isoforms of ERI-1 are localized to the cytoplasm, and each has distinct functions in ribosomal RNA processing and negative regulation of RNA interference.

ERI1 Antigen Profile

Protein Summary

RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Probably acts by degrading the 3'-overhangs of short interfering RNAs (siRNAs). Its tissue specificity may help explain the inefficiency of neuronal RNAi.

Gene names and symbols associated with ERI1

  • three prime histone mRNA exonuclease 1 (THEX1) antibody
  • three prime repair exonuclease 1 (CpipJ_CPIJ003945) antibody
  • three prime histone mRNA exonuclease 1 (LOC100230265) antibody
  • exoribonuclease 1 (eri1) antibody
  • exoribonuclease 1 (ERI1) antibody
  • exoribonuclease 1 (Eri1) antibody
  • Protein ERI-1 (eri-1) antibody
  • 3'hexo antibody
  • 3110010F15Rik antibody
  • eri-1 antibody
  • HEXO antibody
  • RGD1308378 antibody
  • Thex1 antibody
  • zgc:110635 antibody

Protein level used designations for ERI1

three prime histone mRNA exonuclease 1 , three prime repair exonuclease 1 , 3'-5' exoribonuclease 1 , 3' exoribonuclease , histone mRNA 3' end-specific exonuclease , 3'-5' exonuclease ERI1 , Eri-1 homolog , enhanced RNAi three prime mRNA exonuclease homolog 1 , histone mRNA 3'-end-specific exoribonuclease , histone mRNA 3'-exonuclease 1 , protein 3'hExo , three prime mRNA exonuclease 1 , enhanced RNAi protein 1 , eri-1 homolog , 3 ' exoribonuclease

GENE ID SPECIES
463978 Pan troglodytes
6035619 Culex quinquefasciatus
100230265 Taeniopygia guttata
553641 Danio rerio
734610 Xenopus laevis
422629 Gallus gallus
90459 Homo sapiens
540728 Bos taurus
67276 Mus musculus
361159 Rattus norvegicus
176868 Caenorhabditis elegans
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