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anti-Exosome Component 10 (EXOSC10) Antibodies

Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. Additionally we are shipping Exosome Component 10 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EXOSC10 5394 Q01780
EXOSC10 50912 P56960
EXOSC10 313707  
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Top anti-Exosome Component 10 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-EXOSC10 Antibody Titration: 5.0ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC, WB EXOSC10 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of intestinal villus (arrows) in Human Intestine. Magnification is at 400X EXOSC10 antibody used at 5 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated WB EXOSC10 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged EXOSC10 is approximately 1ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$463.83
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated IHC, ELISA   50 μL Log in to see 9 to 11 Days
$313.50
Details

EXOSC10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Exosome Component 10 Antibodies

  1. Cow (Bovine) Polyclonal EXOSC10 Primary Antibody for WB - ABIN2778684 : van Dijk, Schilders, Pruijn: Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways. in RNA (New York, N.Y.) 2007 (PubMed)

  2. Cow (Bovine) Polyclonal EXOSC10 Primary Antibody for IHC, WB - ABIN2778683 : Lehner, Sanderson: A protein interaction framework for human mRNA degradation. in Genome research 2004 (PubMed)

More Antibodies against Exosome Component 10 Interaction Partners

Human Exosome Component 10 (EXOSC10) interaction partners

  1. Rrp6: Integrated roles in nuclear RNA metabolism and transcription termination

  2. EXOSC10 can be modified by SUMOylation and identifies a physiological stress where this regulation is prevalent both in vitro and in vivo.

  3. Results show that DGCR8 (show DGCR8 Antibodies) forms an alternative complex with the RRP6-containing form of the exosome, acts as an adaptor to recruit the exosome to target structured RNAs, and the DGCR8 (show DGCR8 Antibodies)/hRRP6 complex controls the stability of human telomerase RNA.

  4. Microprocessor orchestrates the recruitment of termination factors Setx (show SETX Antibodies) and Xrn2 (show XRN2 Antibodies), and the 3'-5' exoribonuclease, Rrp6, to initiate RNAPII pausing and premature termination at the HIV-1 promoter through cleavage of the stem-loop RNA, TAR (show RBM8A Antibodies).

  5. Systemic sclerosis patients with anti-PM-Scl antibody are younger and significantly more often have limited cutaneous involvement, skeletal muscle disease, pulmonary fibrosis and calcinosis.

  6. Saccharomyces cerevisiae Rrp6, and determined the X-ray structure of a human construct containing the exoribonuclease and HRDC domains that retains catalytic activity

  7. cloning of a more complete cDNA for PM/Scl-75 (show EXOSC9 Antibodies) encoded 84 additional amino acids at its N terminus and only this longer polypeptide is able to associate with the exosome complex.

  8. Although not required for exosome stability, PM/Scl-100 and PM/Scl-75 (show EXOSC9 Antibodies) are involved in mRNA degradation.

  9. Anti-PM/Scl antibodies are common in distinct SSc (show CYP11A1 Antibodies) subsets and are associated with several clinical symptoms

  10. PM-Scl-75 (show EXOSC9 Antibodies) is the main autoantigen in patients with the polymyositis/scleroderma overlap syndrome.

Exosome Component 10 (EXOSC10) Antigen Profile

Protein Summary

Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3'-5' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA (By similarity).

Gene names and symbols associated with EXOSC10

  • exosome component 10 (exosc10) antibody
  • exosome component 10 (EXOSC10) antibody
  • exosome component 10 (EHI_021400) antibody
  • exosome component 10 (BBOV_IV002650) antibody
  • exosome component 10 (CpipJ_CPIJ003896) antibody
  • exosome component 10 (CMU_031760) antibody
  • 3'-5' exonuclease (exosc10) antibody
  • exosome component 10 (Tsp_05247) antibody
  • Exosome component 10 (exosx) antibody
  • exosome component 10 (Exosc10) antibody
  • 21.m02990 antibody
  • 201.t00018 antibody
  • DDBDRAFT_0203581 antibody
  • DDBDRAFT_0233752 antibody
  • DDB_0203581 antibody
  • DDB_0233752 antibody
  • EXOSC10 antibody
  • p2 antibody
  • p3 antibody
  • p4 antibody
  • PM-Scl antibody
  • PM/Scl-100 antibody
  • PMSCL antibody
  • PMSCL2 antibody
  • RRP6 antibody
  • Rrp6p antibody
  • zgc:55695 antibody

Protein level used designations for EXOSC10

exosome component 10 , Exosome component 10 , P100 polymyositis-scleroderma overlap syndrome-associated autoantigen , autoantigen PM-SCL , autoantigen PM/Scl 2 , polymyositis/scleroderma autoantigen 100 kDa , polymyositis/scleroderma autoantigen 2 (100kD) , polymyositis/scleroderma autoantigen 2, 100kDa , autoantigen PM/Scl 2 homolog , polymyositis/scleroderma autoantigen 2 homolog

GENE ID SPECIES
394064 Danio rerio
407941 Xenopus (Silurana) tropicalis
419454 Gallus gallus
457944 Pan troglodytes
478233 Canis lupus familiaris
3405059 Entamoeba histolytica HM-1:IMSS
5477649 Babesia bovis T2Bo
6035353 Culex quinquefasciatus
6997478 Cryptosporidium muris RN66
8618039 Dictyostelium discoideum AX4
10913037 Trichinella spiralis
100014127 Monodelphis domestica
100056644 Equus caballus
100195333 Salmo salar
100355915 Oryctolagus cuniculus
100405990 Callithrix jacchus
100467172 Ailuropoda melanoleuca
100511264 Sus scrofa
100547497 Meleagris gallopavo
100593954 Nomascus leucogenys
431865 Xenopus laevis
5394 Homo sapiens
535340 Bos taurus
50912 Mus musculus
313707 Rattus norvegicus
Selected quality suppliers for anti-Exosome Component 10 (EXOSC10) Antibodies
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